Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Prebiotic Supplement Ingredients & Drug Interactions

by BIOHM

Prebiotic Supplement label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prebiotic Supplement against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prebiotic Supplement is a dietary supplement by BIOHM with 4 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.Based on those ingredients, 109 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inulin, Apple Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prebiotic Supplement by BIOHM

Ask about any prescription or over-the-counter medication and we check it for interactions with Prebiotic Supplement by BIOHM — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Prebiotic Supplement by BIOHM

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “BIOHM 19E” is listed as a grouped ingredient — the label gives one combined amount (1,400 mg) without saying how much of each component you get.

BIOHM Prebiotic Supplement contains 4 active ingredients: lipase (a digestive enzyme), peptidase (another enzyme), apple pectin (a soluble fiber), and inulin (a prebiotic fiber). The product also contains a vegetable cellulose capsule as an inactive ingredient.

Pectin and inulin are the ingredients with the most research behind them, while lipase and peptidase are included to support digestive function.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Prebiotic gut health and digestive support.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Irritable bowel syndrome (IBS), Inflammatory bowel disease (IBD), Antibiotic-associated diarrhea — and 4 related terms.
  • The strongest evidence on file: Inulin is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Inflammatory bowel disease (IBD), Dyspepsia.
  • Also on file: Pectin is rated "Insufficient Reliable Evidence To Rate" for Diarrhea, Irritable bowel syndrome (IBS).

The evidence for this product's ingredients is mixed. Apple pectin is possibly effective for high cholesterol, and inulin is possibly effective for obesity, constipation, and diabetes.

Lipase and peptidase have insufficient evidence to rate — we don't have reliable data showing whether they work for their intended purposes in supplement form. If you're looking for help with any of these conditions, talk with your doctor about whether this supplement makes sense alongside your other treatments.

The evidence, ingredient by ingredient Lipase Pectin Inulin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Apple pectin and inulin are generally well tolerated in food amounts, but both commonly cause bloating, gas, and cramping — especially at higher doses. Inulin in particular often triggers digestive upset.

Lipase is also generally well tolerated, though people with serious digestive conditions should use it only under medical guidance. Rare allergic reactions, including anaphylaxis, have been reported with pectin and inulin in sensitive people.

Pregnancy and breastfeeding data are limited: pectin and inulin are likely or possibly safe at food amounts, but concentrated supplement doses haven't been well studied — talk with your doctor before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Lipase Pectin Inulin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Pectin, Inulin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 109 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take digoxin (Lanoxin), a heart medicine — apple pectin may reduce how well your body absorbs it. Also double-check if you use lovastatin or tetracycline antibiotics (both Moderate interactions with pectin) or antidiabetes drugs (Minor interaction with inulin).

The interaction checker below will flag any concerns with your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This prebiotic blend may help with digestion and fiber intake, but it's not risk-free with certain medications — especially digoxin, lovastatin, tetracycline antibiotics, and antidiabetes drugs. Digestive side effects like gas and bloating are common.

Check your medications against the tool on this page before starting, and talk with your pharmacist if you take any heart, antibiotic, cholesterol, or blood-sugar drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prebiotic Supplement, straight from the product label.

Brand BIOHM
Barcode (UPC) 855486007049
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Sep 24, 2021
DSLD ID 255289
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prebiotic Supplement by BIOHM, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
855486007049
IngredientAmount% DV
Lipase0 NP--
Peptidase0 NP--
Apple Pectin0 NP--
Inulin0 NP--
BIOHM 19E1400 mg--

Other ingredients: Vegetable Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Adults 18 and over, take two capsules per day.

Storage

For best results, we recommend you store BIOHM at room temperature.

Precautions

Warnings: As a dietary supplement, consult your healthcare provider before using this product especially if you are pregnant, nursing, or otherwise under medical supervision.

Keep out of reach of children.

Tamper Evident: Do not use if any part of this package is torn, open, or damaged.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Questions? Contact Us: Visit us at BIOHMHealth.com

19E Powered by BIOHM

Formula

Natural extracts & enzymes One-month supply

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prebiotic Supplement by BIOHM label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prebiotic Supplement label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prebiotic Supplement by BIOHM

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BIOHM 19E

1400 mg per serving

Other (inactive) ingredients: Vegetable Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prebiotic Supplement by BIOHM Drug Interactions

Want to check YOUR meds against Prebiotic Supplement?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
109Drugs
23 Moderate 86 Minor

Ingredients driving the most interactions

Inulin 86
Apple Pectin 23

Individual Drug Interactions

The ingredients in Prebiotic Supplement interact with 109 drugs. Click any drug to see the details.

2 of the 4 ingredients in Prebiotic Supplement interact with drugs. Each result below shows which ingredient is responsible. Inulin Apple Pectin

Each ingredient & the kinds of drugs it affects

For each ingredient in Prebiotic Supplement with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin full monograph & interactions

Apple Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Apple Pectin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prebiotic Supplement, from the product label.

BIOHM

See all BIOHM products
Name
BIOHM Health, LLC
Street Address
737 Bolivar Rd, Ste 200
City
Cleveland
State
OH
ZipCode
44115
Web Address
BIOHMHealth.com
Pharmacist Counseling Corner

Prebiotic Supplement by BIOHM: Common Questions

Does Prebiotic Supplement by BIOHM interact with any medications?
Yes. Based on its ingredients, Prebiotic Supplement has a known interaction with 109 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prebiotic Supplement contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me gas or digestive upset?
Very likely, especially at first. Both apple pectin and inulin commonly cause bloating, flatulence, cramping, and loose stools — inulin can be particularly rough on your gut. Starting with a lower dose and gradually increasing it may help your body adjust.
Is this safe if I'm pregnant or breastfeeding?
Inulin and pectin at food amounts are likely safe during pregnancy and breastfeeding, but this is a concentrated supplement — safety at these doses hasn't been well studied. Talk with your doctor or pharmacist for personalized advice before taking it.
Does this actually work for cholesterol or weight loss?
Apple pectin is possibly effective for high cholesterol, and inulin is possibly effective for weight loss and constipation — but the evidence is modest, not conclusive. Talk with your doctor about whether it fits into your overall treatment plan.
What is a prebiotic, and why is it in here?
Prebiotics are fibers that feed your good gut bacteria and may support digestive health. Inulin and apple pectin are both prebiotics. This product pairs them with digestive enzymes (lipase and peptidase) to support overall gut function, though the enzymes themselves lack strong evidence.
Can I take this with my blood pressure or heart medication?
If your heart medication is digoxin (Lanoxin), do not take this product without checking with your pharmacist first — apple pectin may interfere with how much digoxin your body absorbs. Use the interaction checker on this page with your exact medication names.
Are there any fillers or additives in here?
The only inactive ingredient listed is the vegetable cellulose capsule itself. The four active ingredients make up the rest of the formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prebiotic Supplement is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prebiotic Supplement label
Go deeper

The Full Monographs Behind Prebiotic Supplement’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph → Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph →
Sources

Sources & How We Checked

Prebiotic Supplement's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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