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Dietary supplement

Reducose Ingredients & Drug Interactions

by Phynova

Reducose label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Reducose against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Reducose is a dietary supplement by Phynova with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are White Mulberry leaf water extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Reducose by Phynova

Ask about any prescription or over-the-counter medication and we check it for interactions with Reducose by Phynova — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Reducose by Phynova

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Reducose is a single-ingredient supplement containing white mulberry leaf water extract. This is a concentrated extract from the leaves of the white mulberry plant, which has been used traditionally in herbal medicine.

The tablet also contains several inactive ingredients—microcrystalline cellulose, calcium carbonate, silica, vegetable stearate, croscarmellose sodium, hydroxypropyl methylcellulose, potato starch, maltodextrin, polyvinyl alcohol, talc, macrogol, and polysorbate—which are common fillers, binders, and capsule materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see White Mulberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support normal healthy blood sugar response.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), glycemic control, postprandial glucose, insulin sensitivity.
  • The closest evidence on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (prediabetes).

The evidence on white mulberry leaf for any condition is insufficient to rate in our data. We hold effectiveness ratings for androgenic alopecia (hair loss), osteoporosis, common cold, diabetes, and high cholesterol, but none of them show enough reliable evidence to make a confident claim.

That doesn't mean the ingredient doesn't work—it means the clinical studies available aren't solid enough for us to call it effective or not.

The evidence, ingredient by ingredient White Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, white mulberry leaf is generally well tolerated. The most common side effects in a clinical trial were bloating and flatulence (reported in about half the participants), loose stools (about a quarter), and constipation (about a fifth)—but these tended to improve over the course of the 12-week study, so for some people they may ease up over time.

Regarding pregnancy and breastfeeding, the safety data isn't there. The facts advise against medicinal amounts during pregnancy and breastfeeding.

If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient White Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — White Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Reducose, double-check with your doctor or pharmacist if you're on any antidiabetes drugs (like insulin, metformin, or sulfonylureas)—white mulberry leaf can lower your blood sugar and increase the risk of hypoglycemia. Also flag any medications that are OCT2 substrates, a group of kidney-transport drugs, because white mulberry leaf may slow their elimination and raise their side effects.

These are Moderate-severity interactions worth discussing before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Reducose is a straightforward single-ingredient supplement with side effects that tend to be mild and temporary. The main caution is if you take diabetes medication or kidney-transport drugs—you'll need to discuss this with your own doctor or pharmacist before starting, because white mulberry leaf can affect how those medications work.

Since the evidence on its effectiveness isn't established in our data, consider talking with your healthcare provider about whether it's the right choice for what you're trying to do.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Reducose, straight from the product label.

Brand Phynova
Net contents 60 Vegetarian Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 235582
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Reducose by Phynova, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
White Mulberry leaf water extract250 mg--

Other ingredients: Microcrystalline Cellulose, Calcium Carbonate, Silica, Vegetable Stearate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Potato Starch, Maltodextrin, Polyvinyl Alcohol, Talc, Macrogol, Polysorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Support a normal, healthy blood sugar response May provide support for normal insulin utilization May help reduce the digestion and absorption of carbohydrate

No preservatives, no artificial flavours, no wheat, gluten free, no dairy, non-GMO, suitable for vegetarians.

No preservatives, no artificial flavours, no wheat, gluten free, no dairy, non-GMO, suitable for vegetarians.

Reducose may provide support for normal insulin utilization.

Formula

Clinically studied white mulberry leaf extract

Reducose is a patent-protected and clinically studied extract of white mulberry leaf that has been scientifically formulated to support a normal, healthy blood sugar response in healthy individuals.

General Statements

(4 packets x 15 tablets) 30-day supply

Keep this carton for directions and safety information.

Phynova, a Life Science company specializing in plant-derived products, was founded in Oxford, UK in 2002. Phynova turns the nutritional power from plants into next generation solutions that restore and maintain balance in human health.

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FDA Statement of Identity

Dietary Supplement

Precautions

Warnings: Keep out of reach of children

Consult your physician prior to using this product if you are pregnant, nursing, or if you are taking blood glucose lowering medication, or have a medical condition.

Suggested/Recommended/Usage/Directions

Do not exceed recommended dose

Directions: Take one tablet before a carbohydrate or sugar rich meal. For best results, take 20 minutes before eating.

When taken before a meal, Reducose inhibits the enzymes that break carbohydrates and sugar into glucose, resulting in less glucose getting into the blood.

Storage

Store in a cool, dry place. Moisture may affect the product quality. Please ensure proper re-sealing of the packet after opening.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. The product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practices

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Reducose by Phynova label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Reducose label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Reducose by Phynova

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

White Mulberry leaf water extract

Interacts with
87 drugs
250 mg per serving

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...

White Mulberry leaf water extract monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Calcium Carbonate, Silica, Vegetable Stearate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Potato Starch, Maltodextrin, Polyvinyl Alcohol, Talc, Macrogol, Polysorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Reducose by Phynova Drug Interactions

Want to check YOUR meds against Reducose?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

White Mulberry leaf water extract 87

Individual Drug Interactions

The ingredients in Reducose interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in Reducose interact with drugs. Each result below shows which ingredient is responsible. White Mulberry leaf water extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Reducose with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Mulberry leaf water extract2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
White Mulberry leaf water extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Reducose, from the product label.

Phynova

See all Phynova products
Name
Phynova USA, LLC
Street Address
16625 Redmond Way, Ste. M #314
City
Redmond
State
WA
ZipCode
98052
Phone Number
509-761-9261
Web Address
www.phynova.com
Pharmacist Counseling Corner

Reducose by Phynova: Common Questions

Does Reducose by Phynova interact with any medications?
Yes. Based on its ingredients, Reducose has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Reducose contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does white mulberry leaf actually do?
White mulberry leaf is the only active ingredient in Reducose. Clinical research shows it can lower blood glucose levels, but the evidence on whether it effectively treats any condition isn't strong enough for us to rate it. Talk with your doctor about what you're hoping to address and whether this ingredient makes sense for you.
Can I take Reducose if I'm on metformin for diabetes?
Not without talking to your doctor first. White mulberry leaf can lower blood sugar on its own and may also slow how your kidneys clear metformin—both of which could make your glucose drop too far. Your doctor or pharmacist needs to know you're considering this so they can advise you and adjust monitoring if needed.
What are the side effects?
The most common ones are bloating, flatulence, loose stools, and constipation. In a clinical trial, about half the participants reported bloating or gas, a quarter had loose stools, and a fifth had constipation—but these tended to ease up over time. For most people they're mild and temporary.
Is it safe in pregnancy or while breastfeeding?
The safety data isn't there. The product information advises against medicinal amounts of white mulberry leaf during pregnancy and breastfeeding. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist—they can help you weigh what's known and what's not.
What are the inactive ingredients?
The tablet also contains microcrystalline cellulose, calcium carbonate, silica, vegetable stearate, croscarmellose sodium, hydroxypropyl methylcellulose, potato starch, maltodextrin, polyvinyl alcohol, talc, macrogol, and polysorbate—these are standard binders and fillers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Reducose is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Reducose label
Go deeper

The Full Monographs Behind Reducose’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph →
Sources

Sources & How We Checked

Reducose's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Mulberry 6 references
  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed

See these in context on the White Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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