Rooibos Alcohol Free Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Rooibos Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Rooibos Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for caffeine-free beverage, antioxidant support, heart health.Based on those ingredients, 881 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rooibos Leaf Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Rooibos Alcohol Free by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Rooibos Alcohol Free by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Rooibos Alcohol Free by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
The only active ingredient is rooibos leaf extract, dry, a concentrated form of the rooibos plant. Our data lists one active ingredient in total.
The inactive ingredients are glycerin and water.
Does it work?
Couldn't assess
Rooibos has been studied for age-related cognitive decline, allergic rhinitis (hay fever), anxiety, cancer, cardiovascular disease, and diabetes. For each of these, the evidence we hold is rated Insufficient Reliable Evidence To Rate, so we cannot say whether it works for any of them.
How safe is it?
Well-documented data
Rooibos tea is generally well tolerated in normal beverage amounts. Concentrated extracts like this one have not been well studied, so the data calls for caution with them.
Large, long-term doses of the tea may harm the liver in some susceptible people. One case report described a 37-year-old man who drank 10 cups a day for over a year and developed liver dysfunction and low platelet counts.
For pregnancy and breastfeeding, our data has no entry on file for this ingredient, so there isn't enough information to know either way. Please talk with your doctor or pharmacist about your situation.
Meds to double-check
Moderate interaction found
Double-check medications broken down by CYP2C19, CYP1A2, CYP2D6, CYP2C9, or CYP3A4, plus ACE inhibitors and atorvastatin. Every interaction in our data is rated Moderate, and none are documented at the Major level.
Ask your own doctor or pharmacist before combining this product with any of them.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This may appeal to people who enjoy rooibos as an everyday beverage in normal amounts. Anyone taking medications broken down by CYP enzymes, ACE inhibitors, or atorvastatin should be careful, as should anyone who is pregnant, breastfeeding, or has liver concerns.
Please talk it over with your own doctor or pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Rooibos Alcohol Free, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7238361192338 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 324501 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Rooibos Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Rooibos Leaf Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Aspalathus linearis
FDA Statement of Identity
Herbal Supplement
General Statements
Organic raw material.
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Rooibos Alcohol Free by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Rooibos Alcohol Free by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Rooibos Leaf Extract, Dry
Interacts with881 drugs
Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early...
Rooibos Leaf Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Rooibos Alcohol Free by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Herbal Terra Rooibos Alcohol Free interacts with several medications through its rooibos leaf extract.
The most serious interactions in our data are rated Moderate. They involve the liver enzymes (cytochrome P450 enzymes) that clear many drugs, along with ACE inhibitors (blood pressure medications) and atorvastatin (Lipitor, a cholesterol medication).
Read the full breakdown — every affected drug type, severity by severity
Theoretically, rooibos may increase the effects of drugs broken down by CYP2C19, CYP1A2, CYP2D6, CYP2C9, and CYP3A4, all rated Moderate. Lab research shows the extract inhibits these enzymes.
For ACE inhibitors, also rated Moderate, rooibos may increase both therapeutic and adverse effects, and a single 400 mL dose of tea inhibited enzyme activity in a clinical study of healthy adults. For atorvastatin, rated Moderate, animal research found green rooibos extract raised its peak blood concentration sixfold and reduced how quickly the body cleared it.
Altogether, these interactions span 882 individual medications.
To see whether your exact medications are included, use the search tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Rooibos Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Rooibos Alcohol Free interact with 881 drugs. Click any drug to see the details.
1 of the 1 ingredient in Rooibos Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Rooibos Leaf Extract, Dry
KetoconazoleNizoral
How Ketoconazole interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Ketoconazole interactionLacosamideMotpoly XR, Vimpat
How Lacosamide interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lacosamide interactionLansoprazolePrevacid
How Lansoprazole interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lansoprazole interactionLansoprazole, Amoxicillin, ClarithromycinPrevpac
How Lansoprazole, Amoxicillin, Clarithromycin interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
Read the full Rooibos Leaf Extract, Dry + Lansoprazole, Amoxicillin, Clarithromycin interactionLapatinibTykerb
How Lapatinib interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lapatinib interactionLarotrectinibVitrakvi
How Larotrectinib interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Larotrectinib interactionLefamulin AcetateXenleta
How Lefamulin Acetate interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lefamulin Acetate interactionLemborexantDayvigo
How Lemborexant interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lemborexant interactionLenacapavirSunlenca
How Lenacapavir interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lenacapavir interactionLeniolisibJoenja
How Leniolisib interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Leniolisib interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lercanidipine Hydrochloride interactionLesinuradZurampic
How Lesinurad interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
Read the full Rooibos Leaf Extract, Dry + Lesinurad interactionLesinurad, AllopurinolDuzallo
How Lesinurad, Allopurinol interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
Read the full Rooibos Leaf Extract, Dry + Lesinurad, Allopurinol interactionLetrozoleFemara
How Letrozole interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Letrozole interactionLetrozole, Ribociclib SuccinateKisqali Femara Co-Pack
How Letrozole, Ribociclib Succinate interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Letrozole, Ribociclib Succinate interactionLeuprolide Acetate, Norethindrone AcetateLupaneta Pack
How Leuprolide Acetate, Norethindrone Acetate interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Leuprolide Acetate, Norethindrone Acetate interactionLevamlodipineConjupri
How Levamlodipine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Levamlodipine interactionLevobupivacaineChirocaine
How Levobupivacaine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Levobupivacaine interactionLevomilnacipranFetzima
How Levomilnacipran interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Levomilnacipran interactionLevonorgestrelKyleena, Levonelle 1500, Levonelle One Step, Liletta, Mirena, Norgeston +2 more
How Levonorgestrel interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Levonorgestrel interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Levonorgestrel, Ethinyl Estradiol interactionLidocaineDilocaine, Duo-Trach Kit, Lidoderm, Lidoject-1, Lidoject-2, Nervocaine +4 more
How Lidocaine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos Leaf Extract, Dry + Lidocaine interactionLisdexamfetamineVyvanse
How Lisdexamfetamine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos Leaf Extract, Dry + Lisdexamfetamine interactionLisinoprilPrinivil, Qbrelis, Zestril
How Lisinopril interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryAce Inhibitors (aceis) Moderate
Interaction Summary
Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Read the full Rooibos Leaf Extract, Dry + Lisinopril interactionLofepramineFeprapax, Gamanil, Lomont, Tymelyt
How Lofepramine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
Read the full Rooibos Leaf Extract, Dry + Lofepramine interactionLofexidine HydrochlorideLucemyra
How Lofexidine Hydrochloride interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lofexidine Hydrochloride interactionLomitapideJuxtapid
How Lomitapide interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lomitapide interactionLonafarnibZokinvy
How Lonafarnib interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lonafarnib interactionLopinavir, RitonavirKaletra
How Lopinavir, Ritonavir interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Lopinavir, Ritonavir interactionLoratadineClaritin
How Loratadine interacts with Rooibos Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Rooibos Leaf Extract, DryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
Read the full Rooibos Leaf Extract, Dry + Loratadine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Rooibos Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Rooibos Leaf Extract, Dry
Ace Inhibitors (Aceis)
Theoretically, taking rooibos with ACEIs may increase the therapeutic and adverse effects of ACEIs.
Clinical research in healthy adults shows that taking a single dose of rooibos tea, 400 mL orally, inhibits angiotensin-converting enzyme activity.
Atorvastatin (Lipitor)
Theoretically, taking rooibos with atorvastatin may increase the therapeutic and adverse effects of atorvastatin.
Animal research shows that consuming green rooibos extract with atorvastatin daily for 3 weeks increases the maximum plasma concentration of atorvastatin by 6-fold and reduces the clearance of atorvastatin.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, taking rooibos with CYP1A2 substrates may increase the effects of CYP1A2 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP1A2 enzyme activity.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, taking rooibos with CYP2C19 substrates may increase the effects of CYP2C19 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP2C19 enzyme activity.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, taking rooibos with CYP2D6 substrates may increase the effects of CYP2D6 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2D6 enzyme activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, taking rooibos with CYP3A4 substrates may increase the effects of CYP3A4 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems strongly inhibits CYP3A4 enzyme activity.
Brand information
Manufacturer and brand details for Rooibos Alcohol Free, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Rooibos Alcohol Free by Herbal Terra: Common Questions
Does Rooibos Alcohol Free by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this product safe during pregnancy?
Can rooibos affect the liver?
Does rooibos extract work for any health condition?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Rooibos Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Rooibos Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Rooibos Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Rooibos 4 references
- Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.
- Persson IA, Persson K, Hägg S, Andersson RG. Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers. Public Health Nutr. 2010;13(5):730-7. PubMed
- Reddy S, Mishra P, Qureshi S, Nair S, Straker T. Hepatotoxicity due to red bush tea consumption: a case report. J Clin Anesth. 2016;35:96-98. PubMed
- Patel O, Muller CJF, Joubert E, et al. Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats. Front Pharmacol. 2019;10:1243. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC