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Dietary supplement

Rutin Powder Ingredients & Drug Interactions

by PureBulk.com

Rutin Powder label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rutin Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rutin Powder is a dietary supplement by PureBulk.com with 1 active ingredient. Its ingredients are commonly taken for varicose veins and chronic venous insufficiency, hemorrhoids, easy bruising and fragile capillaries.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rutin powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Rutin Powder by PureBulk.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Rutin Powder by PureBulk.com — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Rutin Powder by PureBulk.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Rutin Powder contains a single active ingredient: rutin powder. Rutin is a plant compound (flavonoid) that comes from citrus, berries, and other sources.

There are no other active ingredients and no inactive fillers listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rutin product and its label doesn't state a use — see Rutin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for rutin is not established in the data we hold. It has been studied for aging skin, autism spectrum disorder, inflammatory bowel disease, diabetes, exercise-induced respiratory infections, and hemorrhoids, but the research is insufficient to rate it as effective for any of these uses.

That doesn't mean it doesn't work—it means larger or higher-quality human trials are needed to know.

The evidence, ingredient by ingredient Rutin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rutin is generally well tolerated in food and when taken as a supplement short-term, though long-term safety data at supplement doses are limited. A small number of people may experience headache, flushing, or rashes when taking it by mouth.

The safety data for supplement doses during pregnancy are not complete enough to know either way—talk with your doctor or pharmacist about whether to use it while pregnant. Safety during breastfeeding is unknown, so the safety data advises against supplement doses while nursing.

Side effects, ingredient by ingredient Rutin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rutin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug (insulin, metformin, sulfonylureas, or others), check with your doctor or pharmacist before adding rutin. The combination may increase the risk of low blood sugar.

No other medication interactions are documented for the ingredients we checked.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Rutin powder might be worth considering if you're interested in a plant flavonoid for general wellness, but evidence for specific health claims is not yet established. If you take antidiabetes medications, you'll want to discuss this supplement with your doctor or pharmacist first, since rutin may lower blood sugar further.

For pregnancy or breastfeeding, check with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rutin Powder, straight from the product label.

Brand PureBulk.com
Net contents 100 g; 3.53 oz.
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 23327
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rutin Powder by PureBulk.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
650 mg
Maximum serving Sizes:
650 mg
Servings per container
153
IngredientAmount% DV
Rutin powder650 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Derived from Sophora japonica L.

US Standard Measuring Spoons Spoon Size (level) milligrams 1/8 teaspoon 344 1/4 teaspoon 688 1/2 teaspoon 1377

Storage

Storage: Keep dry, cool & dark

Formulation

Free of: Sugar, soy, dairy, yeast, gluten, corn and additives.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 650 milligrams (scant 1/4 tsp) once daily, or as directed by physician.

Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rutin Powder by PureBulk.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rutin Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rutin Powder by PureBulk.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size650 mg Dosage formPowder Servings per container153 Amounts shown are per serving.

Rutin powder

Interacts with
86 drugs
650 mg per serving

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins...

Rutin powder monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rutin Powder by PureBulk.com Drug Interactions

Want to check YOUR meds against Rutin Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Rutin powder 86

Individual Drug Interactions

The ingredients in Rutin Powder interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rutin Powder interact with drugs. Each result below shows which ingredient is responsible. Rutin powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Rutin Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rutin powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking rutin with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that rutin has hypoglycemic effects.

Likelihood Possible Evidence D
Rutin powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rutin Powder, from the product label.

PureBulk.com

See all PureBulk.com products
Name
PureBulk.com
City
Roseburg
State
OR
ZipCode
97471
Phone Number
(541) 679-1500
Web Address
PureBulk.com
Pharmacist Counseling Corner

Rutin Powder by PureBulk.com: Common Questions

Does Rutin Powder by PureBulk.com interact with any medications?
Yes. Based on its ingredients, Rutin Powder has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rutin Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take rutin powder while pregnant?
Rutin is rated likely safe in pregnancy based on available data. However, the evidence isn't complete, so it's worth talking it over with your doctor or pharmacist to make sure it's right for your situation.
Is rutin safe while breastfeeding?
Safety during breastfeeding is unknown. The safety data advises against taking rutin supplement doses while nursing—check with your doctor or pharmacist first.
What are the side effects of rutin powder?
A small number of people may experience headache, flushing, or rashes when taking rutin by mouth. Long-term safety data at supplement doses are limited, so watch for any unusual symptoms and report them to your pharmacist.
Does rutin actually work for anything?
The evidence isn't strong enough yet to say rutin is effective for the conditions it's been studied for—aging skin, diabetes, hemorrhoids, and others. That doesn't mean it won't help, just that we need better research to know.
I take diabetes medication. Can I use this?
Rutin may lower blood sugar on its own, so taking it with antidiabetes drugs might increase your risk of low blood sugar. Talk with your doctor or pharmacist before starting—they can decide if it's safe for you and whether monitoring or a dose change is needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rutin Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rutin Powder label
Go deeper

The Full Monographs Behind Rutin Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rutin

Interacts with 86 drugs

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins and hemorrhoids. The evidence is limite...

Read the full Rutin monograph →
Sources

Sources & How We Checked

Rutin Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rutin 2 references
  1. Mehta DK (Ex Ed). British National Formulary, Number 37. British Medical Association and Royal Pharmaceutical Society of Great Britain: London, England, March 1999.
  2. Sun C, Wang L, Sun J, Wang Z, Tang Z. Hypoglycemic and hypolipidemic effects of rutin on hyperglycemic rats. J Tradit Chin Med. 2020;40(4):640-645.

See these in context on the Rutin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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