Sea Mussel Extract Ingredients & Drug Interactions
by NOW
What is this page for?
First and foremost: checking Sea Mussel Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sea Mussel Extract is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for osteoarthritis joint pain, rheumatoid arthritis symptoms, joint stiffness and mobility.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Sea Mussel Extract by NOW
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: mussel extract derived from New Zealand green-lipped mussels. The capsule shell and fillers — gelatin, cellulose, magnesium stearate, and silica — are inactive ingredients that help deliver the extract.
Does it work?
Not established
The evidence isn't established for what this mussel extract is meant to do. Our data shows insufficient reliable evidence to rate its use for asthma, ADHD, breast cancer, or exercise-induced muscle soreness.
If you're considering it for one of those purposes, talk with your pharmacist or doctor about whether the current research supports it for your situation.
How safe is it?
Well-documented data
New Zealand green-lipped mussel is generally well tolerated by most people when taken by mouth. The most common side effects are stomach upset — abdominal pain, acid reflux, diarrhea, flatulence, and nausea — and they're usually mild.
Rare cases of liver injury (hepatitis) and abnormal liver function have been reported with certain mussel extracts, so if you have liver disease or take medications that affect your liver, mention this product to your pharmacist. Anyone with a shellfish allergy should avoid it entirely.
The safety data doesn't support use during pregnancy or while breastfeeding, so if you're pregnant or nursing, skip this one and talk with your doctor.
Meds to double-check
No known interactions
No interactions are documented for this product with any medications we could check. That doesn't mean interactions are impossible — just that none are on file.
Your pharmacist can still review it against your exact medications if you'd like to be certain.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
If you don't have a shellfish allergy and can tolerate mild digestive upset, this product is an option to discuss with your pharmacist — especially if you're looking for support with asthma, ADHD, or muscle soreness, though the evidence is thin. Avoid it if you're pregnant, breastfeeding, allergic to shellfish, or have liver concerns.
Always mention it to your pharmacist before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sea Mussel Extract, straight from the product label.
| Brand | NOW |
|---|---|
| Barcode (UPC) | 733739032683 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 25, 2012 |
| DSLD ID | 14839 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sea Mussel Extract by NOW, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Mussel Extract | 500 mg | -- |
Other ingredients: Gelatin, Cellulose, Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols
GMP QUALITY ASSURED
Brand IP Statement(s)
NOW(R) Sea Mussel is a specially prepared and freeze dried product. It is cultivated on marine farms, using pollution-free sea water with regular monitoring of both water and shellfish quality.
Suggested/Recommended/Usage/Directions
SUGGESTED USAGE: As a dietary supplement, take 1 capsule 1 to 4 times daily with food or on an empty stomach. Consider taking this product in combination with NOW(R) Glucosamine, Chondroitin and Celadrin(R).
Precautions
Warning: Persons with a known allergy to shellfish should not use this product.
General Statements
Green Lipped Sea Mussel Extract is naturally rich in mucopolysaccharides, including chondroitin sulfate A, a naturally occurring component of connective tissue and joint structure in humans and animals.*
Please Recycle.
ACTUAL SIZE
SUPPORTS JOINT FUNCTION • Rich in Mucopolysaccharides • Supports Connective Tissue*
Made in the U.S.A.
Natural color variations may occur in this product.
FDA Disclaimer Statement
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Storage
Store in a cool, dry place.
FDA Statement of Identity
A Dietary Supplement
Formula
Contains shellfish derivative (sea mussel).
Formulation
Contains no sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg or preservatives.
General
CODE 3268 V2
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sea Mussel Extract by NOW label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sea Mussel Extract by NOW
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Mussel Extract
No knowninteractions
New Zealand green-lipped mussel is a shellfish-derived supplement rich in omega-3 fats that is mostly used for joint pain and arthritis. Some studies...
Mussel Extract monograph & interactionsOther (inactive) ingredients: Gelatin, Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Sea Mussel Extract by NOW Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Sea Mussel Extract. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Sea Mussel Extract, from the product label.
NOW
See all NOW products- Name
- NOW FOODS
- Street Address
- 395 S. Glen Ellyn Rd.
- City
- Bloomingdale
- State
- IL
- ZipCode
- 60108
- Web Address
- www.nowfoods.com
Sea Mussel Extract by NOW: Common Questions
Does Sea Mussel Extract by NOW interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I have a shellfish allergy?
What side effects should I expect?
Is it safe during pregnancy or while breastfeeding?
Does it actually work for asthma, ADHD, or sore muscles?
Will this interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sea Mussel Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sea Mussel Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sea Mussel Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
New Zealand Green-lipped Mussel 12 references
- Miller T, Wu H. In vivo evidence for prostaglandin inhibitory activity in New Zealand green-lipped mussel extract. N Z Med J 1984;97:355-7.
- Gibson SLM, Gibson RG. The treatment of arthritis with a lipid extract of Perna canaliculus: a randomised trial. Complement Ther Med 1998;6:122-6.
- Gibson RG, Gibson SL, Conway V, Chappell D. Perna canaliculus in the treatment of arthritis. Practitioner 1980;224:955-60.
- Fabrin, B. [Possible toxic hepatitis after intake of an alternative preparation]. Ugeskr.Laeger 6-13-1988;150(24):1474-1475.
- Gibson, R. G. and Gibson, S. L. Green-lipped mussel extract in arthritis. Lancet 2-21-1981;1(8217):439. PubMed
- Ahern, M. J., Milazzo, S. C., and Dymock, R. Granulomatous hepatitis and Seatone. Med J Aust 8-9-1980;2(3):151-152. PubMed
- Croft, J. E. Granulomatous hepatitis and Seatone. Med J Aust 10-4-1980;2(7):401-402. PubMed
- Lau, S., Chiu, P. K., Chu, E. M. Y., Cheng, I. Y. W., Tang, W. M., Man, R. Y. K., and Halpern, G. M. Treatment of knee osteoarthritis with Lyprinol, lipid extract of the green-lipped mussel - a double-blind placebo-controlled study. Progress in Nutrition
- Gruenwald, J., Graubaum, H., Hansen, K., and Grube, B. Efficacy and tolerability of a combination of LYPRINOL and high concentrations of EPA and DHA in inflammatory rheumatoid disorders... eicosapentaenoic acid... decosahexaenoid acid. Advances in Therap PubMed
- Coulson S, Vecchio P, Gramotnev H, Vitetta L. Green-lipped mussel (Perna canaliculus) extract efficacy in knee osteoarthritis and improvement in gastrointestinal dysfunction: a pilot study. Inflammopharmacology 2012;20:71-6. PubMed
- Sukumaran S, Pittman KB, Patterson WK, et al. A phase I study to determine the safety, tolerability and maximum tolerated dose of green-lipped mussel (Perna canaliculus) lipid extract, in patients with advanced prostate and breast cancer. Ann Oncol 2010;2 PubMed
- Lello J, Liang A, Robinson E, et al. Treatment of children's asthma with a lipid extract of the new Zealand green lipped mussel (Perna canaliculus) (Lyprinol®)-A double blind, randomized controlled trial in children with moderate to serve chronic obstruct
See these in context on the New Zealand Green-lipped Mussel monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC