Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Shrumfuzed Watermelon Gummies Ingredients & Drug Interactions

by Shrumfuzed

Shrumfuzed Watermelon Gummies label
See full label image
Gummy Or Jelly Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Shrumfuzed Watermelon Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Shrumfuzed Watermelon Gummies is a dietary supplement by Shrumfuzed with 6 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 519 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mushroom Fruiting Body Extract, Lion's Mane Fruiting Body Extract, Chaga Mushroom fruiting body extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Shrumfuzed Watermelon Gummies by Shrumfuzed

Ask about any prescription or over-the-counter medication and we check it for interactions with Shrumfuzed Watermelon Gummies by Shrumfuzed — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Shrumfuzed Watermelon Gummies by Shrumfuzed

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “Shrumfuzed Proprietary Blend” is a proprietary blend — the label gives one combined amount (800 mg) without saying how much of each component you get.

Shrumfuzed Watermelon Gummies contain six active ingredients. Sodium is an electrolyte essential in small amounts but present here as a potential concern in supplement form.

The gummies also include four medicinal mushroom fruiting body extracts — Lion's Mane (traditionally used to support cognition), Chaga, Reishi, and Cordyceps — and coconut. The product also contains a proprietary blend; its breakdown isn't disclosed on the label.

Beyond the actives, the gummies hold standard inactive ingredients like corn syrup, sugar, pectin, citric acid, and food colorings.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Cystic fibrosis — rated "Likely Effective" (Sodium) (Natural Medicines).
  • On file: Amphotericin B nephrotoxicity — rated "Possibly Effective" (Sodium) (Natural Medicines).

The data on these ingredients' effectiveness for most claimed uses is limited. Lion's Mane, Reishi, and Cordyceps all lack reliable evidence for the health claims commonly made — cognitive support, heart health, athletic performance, and others.

Chaga and coconut similarly show insufficient evidence for their typical uses (heart health, diabetes, weight). Sodium does have solid evidence for cystic fibrosis and some evidence for reducing kidney damage from a specific chemotherapy drug (amphotericin B), but those are not typical reasons someone would take a watermelon gummy.

The bottom line: we can't tell you these will work for the reasons you might want to take them.

The evidence, ingredient by ingredient Sodium Coconut Lion's Mane Mushroom Chaga Reishi Mushroom Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sodium is generally well tolerated at normal dietary amounts, but too much is linked to high blood pressure and heart strain. The safety notes advise against sodium supplements or very high intake without medical guidance.

The mushroom extracts — Lion's Mane, Chaga, Reishi, and Cordyceps — are generally well tolerated short-term when used as foods or teas, though long-term human safety data are limited. Most common side effects include mild gastrointestinal discomfort, nausea, dizziness, and rash.

Chaga carries a rare risk: two cases of kidney failure and one of kidney damage linked to excessive consumption, because chaga contains high oxalate levels. Coconut is generally safe at normal food amounts, but can trigger allergic reactions ranging from hives to life-threatening anaphylaxis in people with coconut sensitivity.

Pregnancy and lactation data are sparse: sodium is rated possibly unsafe, while Lion's Mane, Chaga, Reishi, and Cordyceps have insufficient safety information — the facts advise avoiding them during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Sodium Coconut Lion's Mane Mushroom Chaga Reishi Mushroom Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Cordyceps, Reishi Mushroom, Chaga, Coconut, Sodium, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 519 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist or doctor if you take any of these: blood pressure medications (antihypertensive drugs), blood thinners or antiplatelet drugs, diabetes medications, lithium, corticosteroids, immune-suppressing drugs (immunosuppressants), didanosine, sodium phosphates, or tolvaptan. All carry Moderate-severity interactions except coconut's interaction with diabetes drugs, which is Minor.

If you have a coconut allergy, avoid this product entirely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're on blood pressure medication, diabetes drugs, blood thinners, lithium, corticosteroids, or immune-suppressing medication, you'll want to check this product with your pharmacist or doctor first — the interactions are real and could affect how your drugs work. The mushrooms are generally tolerated but lack strong evidence they'll do what you hope.

Normal dietary sodium is fine; supplemental sodium is another story.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Shrumfuzed Watermelon Gummies, straight from the product label.

Brand Shrumfuzed
Net contents 4 Individually Sealed Shrum Gummy(ies); 16 Gram(s); 0.56 Ounce(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 339542
Product type Botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Shrumfuzed Watermelon Gummies by Shrumfuzed, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Gummy(ies)
Maximum serving Sizes:
1 Gummy(ies)
Servings per container
4
IngredientAmount% DV
Calories11 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Sodium2 mg1%
Added Sugars2 Gram(s)6%
Total Sugars2 Gram(s)--
Lion's Mane Fruiting Body Extract0 NP--
Coconut10 mg--
Chaga Mushroom fruiting body extract0 NP--
Reishi Mushroom Fruiting Body Extract0 NP--
Cordyceps Mushroom Fruiting Body Extract0 NP--
Shrumfuzed Proprietary Blend800 mg--

Other ingredients: Corn Syrup, Sugar, Pectin, Natural & Artificial Color, Natural & Artificial flavoring, Citric Acid, Sodium Citrate, Blue 1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

4 Pack

Scan QR for COA

Formula

Shrumfuzed Watermelon Gummies 3200 mg total 800 mg each Lions mane chaga cordyceps reishi + Trippy compounds

Precautions

Must age 21 and over

This packaging is child resistant.

Must be 21 years of age and over to purchase and consume this product. Keep away from children and pets.

Do not use this product if you are pregnant or nursing.

If consumed, may cause drowsiness. Never attempt to operate heavy machinery or a moving vehicle while using this product.

Consult with your healthcare provider before consuming this product if you have been prescribed any psychiatric medications.

Intoxicating effects of this product may be delayed. May cause spiritual experience, hallucinations, distortion of reality. Potential side effects of this product include nausea, increased heart rate, paranoia. The purchaser of this product bears all risk and assumes all liability associate with the use, purchase and possession of this product.

Take caution. Please use responsibly

Childproof Not safe for kids

Suggested/Recommended/Usage/Directions

Suggested use: Consume 1 gummy to start to establish individual tolerance. Increase dose in increments to achieve desired affect. To open, bend package at perforations to reveal foil. Use finger to peel away foil at the corner.

FDA Disclaimer Statement

Warning: These statements have not been approved by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Does not contain psilocybin or cannabinoids. Does not contain Amanita muscaria or any of its components.

This product does not contain any scheduled substance and is not illegal to possess.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Shrumfuzed Watermelon Gummies by Shrumfuzed label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Shrumfuzed Watermelon Gummies label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Shrumfuzed Watermelon Gummies by Shrumfuzed

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container4 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sodium

Interacts with
205 drugs
2 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Coconut

Interacts with
86 drugs
10 mg per serving Form: Medium Chain Triglyceride Oil

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses...

Coconut monograph & interactions

Other (inactive) ingredients: Corn Syrup, Sugar, Pectin, Natural & Artificial Color, Natural & Artificial flavoring, Citric Acid, Sodium Citrate, Blue 1. These complete the product’s ingredient list but are not active constituents.

Interaction report

Shrumfuzed Watermelon Gummies by Shrumfuzed Drug Interactions

Want to check YOUR meds against Shrumfuzed Watermelon Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
519Drugs
511 Moderate 8 Minor

Ingredients driving the most interactions

Reishi Mushroom Fruiting Body Extract 375
Lion's Mane Fruiting Body Extract 327
Chaga Mushroom fruiting body extract 327
Cordyceps Mushroom Fruiting Body Extract 249
Sodium 205

Individual Drug Interactions

The ingredients in Shrumfuzed Watermelon Gummies interact with 519 drugs. Click any drug to see the details.

6 of the 6 ingredients in Shrumfuzed Watermelon Gummies interact with drugs. Each result below shows which ingredient is responsible. Reishi Mushroom Fruiting Body Extract Lion's Mane Fruiting Body Extract Chaga Mushroom fruiting body extract Cordyceps Mushroom Fruiting Body Extract Sodium Coconut

Each ingredient & the kinds of drugs it affects

For each ingredient in Shrumfuzed Watermelon Gummies with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Mushroom Fruiting Body Extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Mushroom Fruiting Body Extract full monograph & interactions

Lion's Mane Fruiting Body Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Fruiting Body Extract full monograph & interactions

Chaga Mushroom fruiting body extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga Mushroom fruiting body extract full monograph & interactions

Cordyceps Mushroom Fruiting Body Extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps Mushroom Fruiting Body Extract full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Coconut1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
Coconut full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Shrumfuzed Watermelon Gummies, from the product label.

Shrumfuzed

See all Shrumfuzed products
Name
Shrumfuzed
Pharmacist Counseling Corner

Shrumfuzed Watermelon Gummies by Shrumfuzed: Common Questions

Does Shrumfuzed Watermelon Gummies by Shrumfuzed interact with any medications?
Yes. Based on its ingredients, Shrumfuzed Watermelon Gummies has a known interaction with 519 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Shrumfuzed Watermelon Gummies contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will these gummies help with brain fog or memory?
Lion's Mane is traditionally used for cognition, but we don't hold reliable evidence it works for that. The same goes for Reishi and Cordyceps. The data just isn't there yet to say whether they'll help.
I'm allergic to tree nuts — is this safe for me?
The product contains coconut, which the US treats as a tree nut for allergen purposes. Coconut can trigger serious allergic reactions, including anaphylaxis, in people with coconut sensitivity. Skip this one if you have that allergy.
What are the mushrooms actually in here for?
The label doesn't say — there's a proprietary blend, so we can't see the breakdown. The individual mushroom extracts — Lion's Mane, Chaga, Reishi, Cordyceps — are traditionally used for energy, immune support, and general wellness, but solid evidence for any of those is thin.
Can I take this while pregnant or breastfeeding?
Sodium is rated possibly unsafe; Lion's Mane, Chaga, Reishi, and Cordyceps all have insufficient safety data, and the facts advise avoiding them during pregnancy and breastfeeding. Talk to your doctor or pharmacist for personalized advice before taking this.
Is there a lot of sodium in these gummies?
The label doesn't state the sodium amount per gummy, so we can't tell you the dose. If you're watching sodium for blood pressure or heart health, check the label or contact the maker for that number.
What are the most common side effects?
The mushrooms can cause mild gastrointestinal discomfort, nausea, dizziness, or rash. Chaga has a rare risk of kidney damage with excessive use because it's high in oxalate. Most people tolerate these short-term without trouble.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Shrumfuzed Watermelon Gummies label
Go deeper

The Full Monographs Behind Shrumfuzed Watermelon Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph → Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph → Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Shrumfuzed Watermelon Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 94 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sodium 38 references
  1. Garabedian-Ruffalo SM, Ruffalo RL. Drug and nutrient interactions. Am Fam Physician 1986;33:165-74.
  2. Food and Drug Administration Science Background: Safety of Sodium Phosphates Oral Solution. September 17, 2001. Available at: http://www.fda.gov/cder/drug/safety/sodiumphospate.htm
  3. Coton T, Mallaret C, Coilliot C, Carre D, Guisset M. Severe acute ulcerated gastritis induced by salt. Presse Med 2009;38(3):499-500. PubMed
  4. Frings-Meuthen P, Buehlmeier J, Baecker N, et al. High sodium chloride intake exacerbates immobilization-induced bone resorption and protein losses. J Appl Physiol 2011;111(2):537-542. PubMed
  5. Frings-Meuthen P, Baecker N, Heer M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J Bone Miner Res 2008;23(4):517-524. PubMed
  6. Alam S, Johnson AG. A meta-analysis of randomised controlled trials (RCT) among healthy normotensive and essential hypertensive elderly patients to determine the effect of high salt (NaCl) diet of blood pressure. J Hum Hypertens 1999;13(6):367-74.
  7. Boudville N, Ward S, Benaroia M, House AA. Increased sodium intake correlates with greater use of antihypertensive agents by subjects with chronic kidney disease. Am J Hypertens 2005;18(10):1300-5. PubMed
  8. Bennett WM. Drug interactions and consequences of sodium restriction. Am J Clin Nutr 1997;65(2 Suppl):678S-681S. PubMed
  9. Okusa MD, Crystal LJ. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97(4):383-9. PubMed
  10. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for water, potassium, sodium, chloride, and sulfate. Washington, DC: National Academy Press, 2005. Available at: http://www.nap.edu/openbook.php?record_id=10925. DOI
  11. D'Elia L, Rossi G, Ippolito R, Cappuccio FP, Strazzullo P. Habitual salt intake and risk of gastric cancer: a meta-analysis of prospective studies. Clin Nutr 2012;31(4):489-98. PubMed
  12. Goldsmith SR. Hyponatremia in heart failure: time for a trial. J Card Fail 2013;19(6):398-400. PubMed
  13. Willocks L, Brettle R, Keen J, Valentine C, Pinching AJ. Formulations of didanosine (ddI) and salt overload. Lancet 1992;339(8786):190.
  14. Chen L, Zhang Z, Chen W, Whelton PK, Appel LJ. Lower Sodium Intake and Risk of Headaches: Results From the Trial of Nonpharmacologic Interventions in the Elderly. Am J Public Health. 2016;106(7):1270-5. PubMed
  15. Cook NR, Appel LJ, Whelton PK. Lower levels of sodium intake and reduced cardiovascular risk. Circulation. 2014;129(9):981-9. PubMed
  16. Cook NR, Appel LJ, Whelton PK. Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention. J Am Coll Cardiol. 2016;68(15):1609-1617. PubMed
  17. Mente A, O'Donnell M, Rangarajan S, et al. Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies. Lancet. 2016;388(10043):465-75. PubMed
  18. Moosavian SP, Haghighatdoost F, Surkan PJ, Azadbakht L. Salt and obesity: a systematic review and meta-analysis of observational studies. Int J Food Sci Nutr. 2017;68(3):265-277. PubMed
  19. O'Donnell M, Mente A, Rangarajan S, et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med. 2014;371(7):612-23. DOI
  20. Poggio R, Gutierrez L, Matta MG, Elorriaga N, Irazola V, Rubinstein A. Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies. Public Health Nutr. 2015;18(4):695-704. PubMed
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Lion's Mane Mushroom 6 references
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Coconut 10 references
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Chaga 9 references
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See these in context on the Chaga monograph →

Reishi Mushroom 17 references
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Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
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See these in context on the Cordyceps monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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