UNIQUE CoQH 50 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking UNIQUE CoQH 50 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
UNIQUE CoQH 50 mg is a dietary supplement by A.C. Grace Company with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kaneka QH. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against UNIQUE CoQH 50 mg by A.C. Grace Company
Ask about any prescription or over-the-counter medication and we check it for interactions with UNIQUE CoQH 50 mg by A.C. Grace Company — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of UNIQUE CoQH 50 mg by A.C. Grace Company
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
UNIQUE CoQH contains a single active ingredient: Kaneka QH, a proprietary form of coenzyme Q10 at 50 mg per softgel. Coenzyme Q10 is a compound your cells use to generate energy and protect themselves from oxidative damage.
The softgel capsule also contains inactive ingredients including gelatin, glycerin, D-limonene oil, water, caprylic acid, capric acid, caramel, and alpha-lipoic acid. These are excipients that give the softgel its form and aid absorption.
Does it work?
Strong evidence
In our data, coenzyme Q10 is rated likely effective for coenzyme Q10 deficiency—the condition it's designed to address. For other uses, the evidence is more limited: it's rated possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy.
This means there's some clinical research suggesting benefit, but the evidence isn't yet conclusive. If you're considering this for a specific condition, ask your pharmacist which uses have the strongest research behind them.
How safe is it?
Well-documented data
Coenzyme Q10 is generally well tolerated by most adults when used as directed. In clinical trials, no serious adverse effects were reported.
The most common side effects are gastrointestinal—appetite suppression, diarrhea, heartburn, nausea, and vomiting—though these occur in less than 1% of users. Dividing daily doses above 100 mg may help minimize these.
Headache, dizziness, and insomnia have been reported rarely, as have skin reactions like itching or rash in a small number of trial participants. For pregnancy, there isn't enough reliable safety data, so it's best to avoid unless your doctor advises otherwise.
Safety while breastfeeding hasn't been well studied either—talk with your doctor or pharmacist for personalized guidance.
Meds to double-check
Moderate interaction found
Before you start, double-check with your pharmacist if you take any chemotherapy drugs (especially alkylating agents like cyclophosphamide)—coenzyme Q10 may reduce their effectiveness. If you're on warfarin (Coumadin) or another blood thinner, this product could decrease its blood-thinning effect.
Blood pressure medications may also be affected. Use the medication checker below to verify your specific drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
UNIQUE CoQH is a single-ingredient supplement that's generally well tolerated and possibly effective for several conditions including heart health and migraines. If you take warfarin, chemotherapy drugs, or blood pressure medications, check with your pharmacist before starting—coenzyme Q10 can affect how these work.
Anyone who's pregnant, breastfeeding, or managing a chronic condition should discuss this with their doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about UNIQUE CoQH 50 mg, straight from the product label.
| Brand | A.C. Grace Company |
|---|---|
| Barcode (UPC) | 828054777293 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 285414 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for UNIQUE CoQH 50 mg by A.C. Grace Company, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Kaneka QH | 50 mg | -- |
Other ingredients: D-Limonene Oil, Gelatin, Glycerin, Water, Caprylic Acid, Caramel, Capric Acid, Alpha-Lipoic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Ubiquinol Supplement
Formulation
Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and corn. Contains no artificial colors, flavors, or preservatives.
Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third-party quality certifications.
Suggested/Recommended/Usage/Directions
Suggested Use: 1 softgel, 1 to 2 times daily with food or as directed by a healthcare professional.
Brand IP Statement(s)
Kaneka QH reduced form of coenzyme Q10 Kaneka QH is a trademark of Kaneka Corporation
Precautions
Do not use if shrinkwrap is broken or missing.
Keep out of reach of children
Storage
Store in a cool, dry place (59 degrees F-85 degrees F) away from direct light.
General Statements
Doctor Tested: Application-Based Science 50+ Years of Excellence!
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
UNIQUE CoQH 50 mg by A.C. Grace Company label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in UNIQUE CoQH 50 mg by A.C. Grace Company
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.
Kaneka QH
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Kaneka QH monograph & interactionsOther (inactive) ingredients: D-Limonene Oil, Gelatin, Glycerin, Water, Caprylic Acid, Caramel, Capric Acid, Alpha-Lipoic Acid. These complete the product’s ingredient list but are not active constituents.
UNIQUE CoQH 50 mg by A.C. Grace Company Drug Interactions
HelloPharmacist Interaction Report
UNIQUE CoQH by A.C.
Grace Company contains one active ingredient, Kaneka QH (a form of coenzyme Q10), which does interact with certain medications. The most serious concern is with chemotherapy drugs called alkylating agents (like cyclophosphamide).
Because coenzyme Q10 is an antioxidant, it may theoretically reduce how well these cancer drugs work by protecting tumor cells from the oxidative stress these medications rely on to kill cancer cells.
Read the full breakdown — every affected drug type, severity by severity
Coenzyme Q10 also interacts with warfarin (Coumadin), a blood thinner. There's a chemical similarity between coenzyme Q10 and vitamin K, which could reduce warfarin's effectiveness.
Four cases of decreased warfarin effectiveness linked to coenzyme Q10 have been reported in the medical literature.
With blood pressure medications (antihypertensives), coenzyme Q10 may have minor additive effects—meaning it could theoretically add to their blood-pressure-lowering action, though clinical research on this has been mixed.
Altogether, these interactions span 196 individual medications. Use the medication checker on this page to verify your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against UNIQUE CoQH 50 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in UNIQUE CoQH 50 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in UNIQUE CoQH 50 mg interact with drugs. Each result below shows which ingredient is responsible. Kaneka QH
AltretamineHexalen
How Altretamine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Kaneka Qh + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Kaneka Qh + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Kaneka Qh + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Kaneka Qh + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Kaneka Qh + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Kaneka Qh + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with UNIQUE CoQH 50 mg — through 1 ingredient. Tap an ingredient for the detail:
Kaneka QhAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Kaneka Qh + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in UNIQUE CoQH 50 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Kaneka QH
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for UNIQUE CoQH 50 mg, from the product label.
A.C. Grace Company
See all A.C. Grace Company products- Name
- A.C. Grace Company
- Street Address
- P.O. BOX 570
- City
- Big Sandy
- State
- TX
- ZipCode
- 75755
- Phone Number
- 903-636-4368
- Web Address
- www.acgrace.com
UNIQUE CoQH 50 mg by A.C. Grace Company: Common Questions
Does UNIQUE CoQH 50 mg by A.C. Grace Company interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is coenzyme Q10 and what does it do in the body?
Does this supplement actually work?
What side effects might I experience?
Is it safe to take during pregnancy or breastfeeding?
Can I take this with my blood pressure medication?
What are the inactive ingredients in this softgel?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if UNIQUE CoQH 50 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind UNIQUE CoQH 50 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
UNIQUE CoQH 50 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
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