Urinary Bladder Support Alcohol Free Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Urinary Bladder Support Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Urinary Bladder Support Alcohol Free is a dietary supplement by Herbal Terra with 4 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,143 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow Leaf Extract, Dry, Uva Ursi Herb Extract, Corn Silk Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Urinary Bladder Support Alcohol Free by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Urinary Bladder Support Alcohol Free by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Urinary Bladder Support Alcohol Free by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains four active ingredients in a liquid form. Marshmallow leaf extract, corn silk extract, and couch root extract are plant-derived compounds traditionally used for urinary and bladder support, along with uva ursi herb extract.
The inactive ingredients are glycerin and water.
Does it work?
Leans against
The evidence for what these ingredients can do is limited. Marshmallow leaf extract, corn silk, and couch root don't have established effectiveness ratings in our data for standard health claims.
Uva ursi is rated possibly ineffective for urinary tract infections (UTIs) — the very condition many people take it for — and we don't have reliable evidence for its use in bronchitis or benign prostatic hyperplasia either.
How safe is it?
Well-documented data
Marshmallow leaf and corn silk are generally well tolerated for short-term use, though human safety data are limited for both. Couch root is also considered generally well tolerated, but again, long-term safety hasn't been thoroughly studied.
Uva ursi can be toxic at high doses or with prolonged use and may cause nausea, vomiting, diarrhea, and stomach upset at any dose — at very high doses (20 grams or more of the dried herb), it's been reported to cause serious effects including convulsions, delirium, and shortness of breath. During pregnancy, the safety data advise against marshmallow leaf, corn silk, and couch root; uva ursi may stimulate the uterus and also should be avoided.
For breastfeeding, marshmallow leaf and uva ursi lack enough safety information and should be avoided; corn silk safety while breastfeeding is unknown, so skip it unless a clinician approves.
Meds to double-check
Moderate interaction found
Check before using this product if you take blood pressure medications (antihypertensive drugs), diabetes medications, diuretics (water pills), lithium, warfarin or other blood thinners, corticosteroids, or medications that acidify your urine. Also double-check if you're on drugs metabolized by CYP2C19 or CYP3A4, or any drug transported by P-glycoprotein — your pharmacist can tell you if yours fit that bill.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product's effectiveness for bladder support isn't established in the data we hold, and one of its key ingredients (uva ursi) is actually rated possibly ineffective for the urinary tract infections many people buy it for. More importantly, it has significant interactions with blood pressure medications, diabetes drugs, diuretics, lithium, warfarin, and several others.
If you take any prescription medications, run them through the checker on this page before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Urinary Bladder Support Alcohol Free, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7439500738770 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Jan 23, 2025 |
| DSLD ID | 324634 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Urinary Bladder Support Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1156 mg | -- |
| Marshmallow Leaf Extract, Dry | 0 NP | -- |
| Corn Silk Extract, Dry | 0 NP | -- |
| Couch Root Extract, Dry | 0 NP | -- |
| Uva Ursi Herb Extract | 0 NP | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.
Natural Gluten free
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
General Statements
Extraction rate: about 1/ 3-4 (up to 333 mg of dry raw material per 1 ml of extract).
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Urinary Bladder Support Alcohol Free by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Urinary Bladder Support Alcohol Free by Herbal Terra
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Urinary Bladder Support Alcohol Free by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Herbal Terra's Urinary Bladder Support Alcohol Free contains four ingredients, three of which have documented interactions with medications.
The most serious concern is corn silk extract, which interacts with antihypertensive drugs (blood pressure medications) at a Moderate severity level — it can lower blood pressure further and raise the risk of excessively low blood pressure (hypotension).
Read the full breakdown — every affected drug type, severity by severity
Corn silk also interacts moderately with corticosteroids (raising the risk of low potassium), antidiabetes drugs (raising the risk of low blood sugar), diuretics (water pills), and warfarin (a blood thinner). Uva ursi herb extract has Moderate interactions with several drug-metabolism pathways — specifically CYP2C19 and CYP3A4 substrates, glucuronidated drugs, and lithium — as well as a Minor interaction with P-glycoprotein substrates.
It also interacts moderately with urinary acidifying agents. Marshmallow leaf extract carries Moderate risk with lithium and Minor risk with oral drugs (due to impaired absorption) and anticoagulant/antiplatelet drugs.
Couch root extract has no known interactions documented in our data. Altogether, these interactions span 2,124 individual medications.
Check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Urinary Bladder Support Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Urinary Bladder Support Alcohol Free interact with 2,143 drugs. Click any drug to see the details.
3 of the 4 ingredients in Urinary Bladder Support Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Leaf Extract, Dry Uva Ursi Herb Extract Corn Silk Extract, Dry
ValdecoxibBextra
How Valdecoxib interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Valdecoxib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Valdecoxib interactionValsartanDiovan, Prexxartan
How Valsartan interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Valsartan interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Valsartan interactionVamoroloneAgamree
How Vamorolone interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vamorolone interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vamorolone interactionVandetanibCaprelsa
How Vandetanib interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vandetanib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vandetanib interactionVanzacaftor, Tezacaftor, DeutivacaftorAlyftrek
How Vanzacaftor, Tezacaftor, Deutivacaftor interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vanzacaftor, Tezacaftor, Deutivacaftor interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vanzacaftor, Tezacaftor, Deutivacaftor interactionVardenafilLevitra, Staxyn
How Vardenafil interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vardenafil interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vardenafil interactionVemurafenibZelboraf
How Vemurafenib interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract + Vemurafenib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vemurafenib interactionVenetoclaxVenclexta
How Venetoclax interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Venetoclax interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Venetoclax interactionVerapamilCalan, Calan SR, Covera HS, Isoptin, Isoptin SR, Veramil +3 more
How Verapamil interacts with Urinary Bladder Support Alcohol Free — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract + Verapamil interactionCorn Silk Extract, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk Extract, Dry + Verapamil interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Verapamil interactionVibegronGemtesa
How Vibegron interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract + Vibegron interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vibegron interactionVilazodoneViibryd
How Vilazodone interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vilazodone interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vilazodone interactionVildagliptinGalvus
How Vildagliptin interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Corn Silk Extract, Dry + Vildagliptin interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vildagliptin interactionVinblastineVelban
How Vinblastine interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract + Vinblastine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vinblastine interactionVincristineVincasar
How Vincristine interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vincristine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vincristine interactionVincristine SulfateMarqibo Kit
How Vincristine Sulfate interacts with Urinary Bladder Support Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi Herb ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Uva Ursi Herb Extract + Vincristine Sulfate interactionVinorelbineNavelbine
How Vinorelbine interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vinorelbine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vinorelbine interactionVoclosporinLupkynis
How Voclosporin interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Voclosporin interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Voclosporin interactionVonoprazan, AmoxicillinVoquezna Dual
How Vonoprazan, Amoxicillin interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vonoprazan, Amoxicillin interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vonoprazan, Amoxicillin interactionVonoprazan, Amoxicillin, ClarithromycinVoquezna Triple
How Vonoprazan, Amoxicillin, Clarithromycin interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vonoprazan, Amoxicillin, Clarithromycin interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vonoprazan, Amoxicillin, Clarithromycin interactionVorapaxarZontivity
How Vorapaxar interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Vorapaxar interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Vorapaxar interactionVoriconazoleVfend
How Voriconazole interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Herb Extract + Voriconazole interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Voriconazole interactionVoxelotorOxbryta
How Voxelotor interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Voxelotor interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Voxelotor interactionWarfarinWarfarin
How Warfarin interacts with Urinary Bladder Support Alcohol Free — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Warfarin interactionCorn Silk Extract, DryWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Read the full Corn Silk Extract, Dry + Warfarin interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Urinary Bladder Support Alcohol Free — through 3 ingredients. Tap an ingredient for the detail:
Corn Silk Extract, DryWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Read the full Corn Silk Extract, Dry + Warfarin Sodium interactionUva Ursi Herb ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Herb Extract + Warfarin Sodium interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Warfarin Sodium interactionZaleplonSonata, Starnoc
How Zaleplon interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Zaleplon interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Zaleplon interactionZanubrutinibBrukinsa
How Zanubrutinib interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Zanubrutinib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Zanubrutinib interactionZileutonZyflo, Zyflo CR
How Zileuton interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Zileuton interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Zileuton interactionZiprasidoneGeodon
How Ziprasidone interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Ziprasidone interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Ziprasidone interactionZolpidemAmbien CR, Intermezzo, Sublinox
How Zolpidem interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Zolpidem interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Zolpidem interactionZolpidem TartrateAmbien
How Zolpidem Tartrate interacts with Urinary Bladder Support Alcohol Free — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Zolpidem Tartrate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Zolpidem Tartrate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Urinary Bladder Support Alcohol Free with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Marshmallow Leaf Extract, Dry
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
Uva Ursi Herb Extract
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Corn Silk Extract, Dry
Antidiabetes Drugs
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.
Antihypertensive Drugs
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.
Corticosteroids
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.
Diuretic Drugs
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.
Warfarin (Coumadin)
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.
Brand information
Manufacturer and brand details for Urinary Bladder Support Alcohol Free, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Urinary Bladder Support Alcohol Free by Herbal Terra: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Urinary Bladder Support Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Marshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph → Herb & supplement monographCorn Silk
Interacts with 290 drugsCorn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...
Read the full Corn Silk monograph → Herb & supplement monographCouch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph →Sources & How We Checked
Urinary Bladder Support Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Marshmallow 5 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.
Corn Silk 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
- Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC