Interactions on record — worth a quick check against your medications. Based on 7 of 12 ingredients. Check your meds →
Dietary supplement

Urinary Care Ingredients & Drug Interactions

by ProBioCare

Urinary Care label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Urinary Care against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Urinary Care is a dietary supplement by ProBioCare with 12 active ingredients. Its ingredients are commonly taken for urinary tract infection prevention, bladder health, antioxidant support.Based on those ingredients, 966 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cranberry extract, B. longum, B. bifidum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Urinary Care by ProBioCare

Ask about any prescription or over-the-counter medication and we check it for interactions with Urinary Care by ProBioCare — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Urinary Care by ProBioCare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 12 active ingredients.
  • “Outer Capsule:” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “Proprietary Bifidobacterium Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Proprietary Lactobacilli Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

ProBioCare Urinary Care is a 12-ingredient capsule centered on live probiotic bacteria and plant-based prebiotics designed to support urinary tract health. The product contains five named Lactobacillus species (L. acidophilus, L. bulgaricus, L. salivarius, L. plantarum, and L. rhamnosus), three Bifidobacterium species (B. longum, B. bifidum, and B. lactis), and supporting ingredients including fructo-oligosaccharides, larch arabinogalactan, and cranberry extract.

The inactive ingredients are medium-chain triglycerides, hypromellose, cellulose, a vegetarian capsule shell, silica, vegetable stearine, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports digestive balance and urinary tract health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Constipation, Diarrhea, urinary tract infection, bladder health — and 1 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis.
  • Also on file: Cranberry is rated "Possibly Effective" for Urinary tract infections (UTIs).

The evidence for this product's ingredients varies. Cranberry extract is possibly effective for urinary tract infections (UTIs), which aligns with the product's purpose.

Among the probiotics, L. acidophilus and B. bifidum are each possibly effective for irritable bowel syndrome, and L. acidophilus is possibly effective for antibiotic-associated diarrhea, bacterial vaginosis, and Helicobacter pylori infection. However, for most other health claims associated with individual ingredients—including cognitive decline, hay fever, asthma, and common cold—the evidence is insufficient to rate them reliably.

The prebiotics (fructo-oligosaccharides and larch arabinogalactan) similarly lack sufficient evidence for osteoporosis, constipation, diabetes, and cholesterol support.

The evidence, ingredient by ingredient Cranberry Bifidobacterium Longum Bifidobacterium Bifidum Lactobacillus Acidophilus Lactobacillus Delbrueckii Fructo-oligosaccharides (fos) Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these ingredients are generally well tolerated in healthy people. The probiotics and prebiotics can cause mild gastrointestinal effects like bloating, flatulence, abdominal discomfort, and gas—especially at higher doses or when first starting.

Cranberry is also generally well tolerated, though at very high doses (3–4 liters of juice daily) it may cause diarrhea and gastrointestinal upset. However, there are rare but serious safety concerns: probiotic bacteria can rarely translocate and cause bloodstream infections (bacteremia or sepsis) in critically ill, immune-compromised, or very young patients.

B. longum and L. acidophilus carry specific case reports of such events in vulnerable populations. For this reason, anyone who is seriously ill, immune-compromised, or a preterm infant should use only under their doctor's close supervision.

Cranberry extract in pregnancy is likely safe, but safety data for the probiotics in pregnancy and breastfeeding are limited—B. longum is rated possibly safe, while B. bifidum and L. acidophilus have no pregnancy/lactation data on file. Consult your doctor or pharmacist before use if you are pregnant or nursing.

Side effects, ingredient by ingredient Cranberry Bifidobacterium Longum Bifidobacterium Bifidum Lactobacillus Acidophilus Lactobacillus Delbrueckii Fructo-oligosaccharides (fos) Larch Arabinogalactan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Lactobacillus Acidophilus, Cranberry, Larch Arabinogalactan, Bifidobacterium Bifidum, Bifidobacterium Longum, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 967 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start ProBioCare Urinary Care, check your medications against these drug types: cytochrome P450 3A4 substrates (a large group including many heart and blood pressure drugs, cholesterol drugs, and immunosuppressants), atorvastatin specifically, nifedipine, warfarin (a blood thinner), antibiotic drugs, immunosuppressants, cytochrome P450 2C9 substrates, and diclofenac. If you take any of these, run them through the checker below.

Spacing your antibiotic doses away from this product can help, but other interactions require closer review with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ProBioCare Urinary Care is designed primarily for urinary tract health (cranberry is possibly effective for UTIs), and the probiotics offer some evidence for specific digestive and bacterial issues. However, if you take blood thinners like warfarin, statins, blood pressure medications, immunosuppressants, or antibiotics, you'll need to check your specific medications with the tool on this page first—the interactions are real and potentially significant.

Anyone who is seriously ill, immune-compromised, pregnant, or breastfeeding should discuss this product with their doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Urinary Care, straight from the product label.

Brand ProBioCare
Barcode (UPC) 766536050529
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Sep 21, 2017
DSLD ID 77907
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Urinary Care by ProBioCare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Veggie Capsule(s)
Maximum serving Sizes:
4 Veggie Capsule(s)
Servings per container
30
UPC/BARCODE
766536050529
IngredientAmount% DV
Calories10 Calorie(s)--
Saturated Fat1 Gram(s)5%
Total Fat1 Gram(s)1%
Trans Fat0 Gram(s)--
B. longum0 NP--
Fructo-Oligosaccharides0 NP--
B. lactis0 NP--
L. salivarius0 NP--
B. bifidum0 NP--
Arabinogalactan0 NP--
L. plantarum0 NP--
L. acidophilus0 NP--
L. rhamnosus0 NP--
L. bulgaricus0 NP--
Outer Capsule:0 NP--
Cranberry extract400 mg--
Inner Capsule:0 NP--
Proprietary Bifidobacterium Blend0 NP--
Proprietary Lactobacilli Blend0 NP--
Prebiotic Blend50 mg--

Other ingredients: Medium Chain Triglycerides, Hypromellose, Cellulose, Vegetarian Capsule, Silica, Vegetable Stearine, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Duocap technology

DUOCAP is a trademark used under license

Formula

Probiotic + cranberry extract 37:1

General Statements

50 billion

Supports digestive balance and urinary tract health

Acid-resistant Active

Per 4 capsule serving

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Formulation

Allergen-free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take four (4) veggie capsules daily, preferably with a meal.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place.

Precautions

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

General

Item No. VS-5052 2120285 GR 53

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Urinary Care by ProBioCare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Urinary Care label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Urinary Care by ProBioCare

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Veggie Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Outer Capsule:

0 NP per serving

Inner Capsule:

0 NP per serving

Proprietary Bifidobacterium Blend

0 NP per serving

Proprietary Lactobacilli Blend

0 NP per serving

Prebiotic Blend

50 mg per serving

Other (inactive) ingredients: Medium Chain Triglycerides, Hypromellose, Cellulose, Vegetarian Capsule, Silica, Vegetable Stearine, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Urinary Care by ProBioCare Drug Interactions

Want to check YOUR meds against Urinary Care?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
966Drugs
900 Moderate 66 Minor

Ingredients driving the most interactions

Cranberry extract 712
B. longum 182
B. bifidum 182
L. acidophilus 182
L. bulgaricus 182

Individual Drug Interactions

The ingredients in Urinary Care interact with 966 drugs. Click any drug to see the details.

6 of the 12 ingredients in Urinary Care interact with drugs. Each result below shows which ingredient is responsible. Cranberry extract B. longum B. bifidum L. acidophilus L. bulgaricus Arabinogalactan

Each ingredient & the kinds of drugs it affects

For each ingredient in Urinary Care with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cranberry extract6 drug types · 712 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
Cranberry extract full monograph & interactions

B. longum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
B. longum full monograph & interactions

B. bifidum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
B. bifidum full monograph & interactions

L. acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
L. acidophilus full monograph & interactions

L. bulgaricus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus delbrueckii with antibiotic drugs might decrease the effectiveness of L. delbrueckii.
Lactobacillus delbrueckii preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. delbrueckii preparations by at least two hours.

Likelihood Probable Evidence D
L. bulgaricus full monograph & interactions

Arabinogalactan1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
Arabinogalactan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Urinary Care, from the product label.

ProBioCare

See all ProBioCare products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

Urinary Care by ProBioCare: Common Questions

Does Urinary Care by ProBioCare interact with any medications?
Yes. Based on its ingredients, Urinary Care has a known interaction with 966 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Urinary Care contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product help prevent or treat urinary tract infections?
Cranberry extract, one of the active ingredients here, is possibly effective for UTIs. However, the data on the probiotic bacteria in this product specifically for UTI prevention are not established in our files. If you have a UTI, you need medical treatment—this product is not a substitute for antibiotics or other prescribed care. Ask your doctor or pharmacist how it might fit into your overall approach.
Can I take this if I'm on an antibiotic?
The live probiotics in this product (all the Lactobacillus and Bifidobacterium species) can be killed by antibiotics if you take them at the same time. You'll want to space them apart—typically at least 2 hours apart, though your pharmacist can give you the best timing for your specific antibiotic. If you're unsure, ask your pharmacist how to use them together safely.
What are the most common side effects?
Mild gastrointestinal effects are the main ones: bloating, flatulence, abdominal discomfort, and gas. These tend to be most noticeable when you first start and often settle down. At very high doses of cranberry, diarrhea has been reported. If you experience unusual or severe symptoms, stop and contact your doctor.
Is it safe to take while pregnant or breastfeeding?
Cranberry extract is likely safe during pregnancy. B. longum is rated possibly safe, but B. bifidum and L. acidophilus don't have enough safety data on file for pregnancy and breastfeeding. Since data are limited, talk with your doctor or pharmacist before using this product while pregnant or nursing—they can weigh the potential benefits for your specific situation.
Does this product have fillers or anything else besides the active ingredients?
Yes, there are inactive ingredients: medium-chain triglycerides, hypromellose, cellulose, the vegetarian capsule shell itself, silica, vegetable stearine, and magnesium stearate. These are standard excipients used to hold and deliver the active ingredients.
I take a statin for cholesterol. Is this product safe for me?
Cranberry extract in this product can theoretically slow how your liver clears certain statins (especially atorvastatin) and raise their levels, which may increase side effects. This is a documented moderate interaction, so you'll want to check your specific statin with the medication checker on this page and talk it over with your pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Urinary Care label
Go deeper

The Full Monographs Behind Urinary Care’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cranberry

Interacts with 712 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph → Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Lactobacillus Delbrueckii

Interacts with 182 drugs

Lactobacillus delbrueckii is a 'friendly' bacterium used in food fermentation and sold as a probiotic, often as part of multi-strain products. It is generally considered safe for healthy peo...

Read the full Lactobacillus Delbrueckii monograph → Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph →
Sources

Sources & How We Checked

Urinary Care's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 99 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Longum 21 references
  1. Ha GY, Yang CH, Kim H, Chong Y. Case of sepsis caused by Bifidobacterium longum. J Clin Microbiol 1999;37:1227-8.
  2. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Rautava S, Kainonen E, Salminen S, Isolauri E. Maternal probiotic supplementation during pregnancy and breast-feeding reduces the risk of eczema in the infant. J Allergy Clin Immunol. 2012;130(6):1355-60. PubMed
  5. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  6. Pellonperä O, Vahlberg T, Mokkala K, et al. Weight gain and body composition during pregnancy: a randomised pilot trial with probiotics and/or fish oil. Br J Nutr. 2020 Nov 4:1-11. PubMed
  7. Pellonperä O, Mokkala K, Houttu N, et al. Efficacy of fish oil and/or probiotic intervention on the incidence of gestational diabetes mellitus in an at-risk group of overweight and obese women: A randomized, placebo-controlled, double-blind clinical trial PubMed
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed
  10. Enomoto T, Sowa M, Nishimori K, et al. Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergol Int 2014;63(4):575-85. PubMed
  11. US Food and Drug Administration (FDA). Dear Healthcare Provider Letter: Warning Regarding Use of Probiotics in Preterm Infants. September 2023. Available at: https://www.fda.gov/media/172606/download?attachment. Accessed November 1, 2023.
  12. Pillai A, Tan J, Paquette V, Panczuk J. Does probiotic bacteremia in premature infants impact clinically relevant outcomes? A case report and updated review of literature. Clin Nutr ESPEN. 2020;39:255-259. PubMed
  13. Sabaté JM, Iglicki F. Effect of Bifidobacterium longum 35624 on disease severity and quality of life in patients with irritable bowel syndrome. World J Gastroenterol 2022;28(7):732-744.
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Fructo-oligosaccharides (fos) 6 references
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See these in context on the Fructo-oligosaccharides (fos) monograph →

Bifidobacterium Bifidum 7 references
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Larch Arabinogalactan 8 references
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See these in context on the Larch Arabinogalactan monograph →

Lactobacillus Acidophilus 15 references
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  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
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See these in context on the Lactobacillus Acidophilus monograph →

Lactobacillus Delbrueckii 9 references
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  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
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Cranberry 33 references
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See these in context on the Cranberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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