Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

White Mulberry Ingredients & Drug Interactions

by Pure Health Naturally

White Mulberry label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking White Mulberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

White Mulberry is a dietary supplement by Pure Health Naturally with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are White Mulberry (Morus alba) Leaf Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against White Mulberry by Pure Health Naturally

Ask about any prescription or over-the-counter medication and we check it for interactions with White Mulberry by Pure Health Naturally — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of White Mulberry by Pure Health Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: white mulberry leaf powder (from Morus alba). Mulberry leaf has been used traditionally to support blood sugar balance and overall wellness.

The capsule itself is vegetarian.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This White Mulberry product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see White Mulberry's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“supports overall health”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence we hold doesn't establish that white mulberry leaf reliably works for any condition — we have insufficient data to rate it for blood sugar control, cholesterol, bone health, hair loss, or cold prevention. While some research suggests it may affect blood glucose, the clinical evidence isn't strong enough for us to make a solid claim about effectiveness.

The evidence, ingredient by ingredient White Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

White mulberry leaf is generally well tolerated when taken by mouth. The most common side effects are temporary digestive issues — bloating, flatulence, loose stools, or constipation.

In one clinical trial, about half of participants reported bloating or gas at the start, but these effects often eased as they continued taking it. Because the supplement can lower blood sugar, use caution if that's a concern for you.

We don't have enough safety data to recommend medicinal amounts during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient White Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — White Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications against these drug types: antidiabetes drugs (because of the risk of low blood sugar) and OCT2 substrate medications (because white mulberry may slow their elimination). Both are Moderate-severity interactions.

Your pharmacist can search your exact medications on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. Moderate medication interactions have been identified, and safety information is well characterized.

White Mulberry by Pure Health Naturally is worth considering if you're exploring traditional support for blood sugar, but the evidence for it isn't established yet. If you take diabetes medications or OCT2 substrate drugs (especially metformin), check with us or your doctor first — this supplement may affect how they work.

Expect possible mild digestive effects at the start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about White Mulberry, straight from the product label.

Brand Pure Health Naturally
Barcode (UPC) 812711013916
Net contents 30 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD May 23, 2014
DSLD ID 33413
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for White Mulberry by Pure Health Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
812711013916
IngredientAmount% DV
White Mulberry (Morus alba) Leaf Powder400 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Pure Health's White Mulberry: - Supports Overall Health*

And Nothing Else!

Due to the natural and pure ingredients in this product, taste, color and consistency may vary.

Formulation

- Vegetarian Capsule

- No Binders, Fillers or Excipients

General

LBPH149

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule 30 minutes before meals or as directed by your healthcare provider.

Precautions

Do not use if seal around cap is broken.

Keep out of reach of children.

Caution: This supplement may increase the effects of blood-sugar lowering medications (e.g., insulin and oral hypoglycemic agents) and side-effects of cholesterol-lowering medications. Those taking prescription anti-depressants and sedatives should use with caution and first seek the advice of a physician. Avoid use if pregnant, lactating or with known hypersensitivity to white mulberry.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

White Mulberry by Pure Health Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

White Mulberry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in White Mulberry by Pure Health Naturally

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

White Mulberry (Morus alba) Leaf Powder

Interacts with
87 drugs
400 mg per serving

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...

White Mulberry (Morus alba) Leaf Powder monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

White Mulberry by Pure Health Naturally Drug Interactions

Want to check YOUR meds against White Mulberry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

White Mulberry (Morus alba) Leaf Powder 87

Individual Drug Interactions

The ingredients in White Mulberry interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in White Mulberry interact with drugs. Each result below shows which ingredient is responsible. White Mulberry (Morus alba) Leaf Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in White Mulberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Mulberry (Morus alba) Leaf Powder2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
White Mulberry (Morus alba) Leaf Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for White Mulberry, from the product label.

Pure Health Naturally

See all Pure Health Naturally products
Name
Pure Health, LLC
Street Address
3753 Howard Hughes Parkway Suite 200, #428
City
Las Vegas
State
NV
ZipCode
89169
Phone Number
(888) 323-9355
Pharmacist Counseling Corner

White Mulberry by Pure Health Naturally: Common Questions

Does White Mulberry by Pure Health Naturally interact with any medications?
Yes. Based on its ingredients, White Mulberry has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
White Mulberry contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will white mulberry lower my blood sugar if I'm not diabetic?
White mulberry leaf can lower blood glucose levels, so theoretically yes — but the effect in people without diabetes isn't well studied. If you're concerned, talk with your pharmacist before starting.
What are the side effects?
Digestive issues are most common: bloating, gas, loose stools, or constipation. In clinical trials, about half of patients had bloating or gas, a quarter had loose stools, and about a fifth had constipation — but these often got better as they kept taking it.
Can I take this if I'm pregnant or breastfeeding?
We don't have enough safety data. The facts advise against medicinal amounts in both cases, so talk with your doctor or pharmacist for personalized advice.
Does this product actually work?
The evidence we hold isn't established for any condition — there's insufficient data to rate it reliably for blood sugar, cholesterol, bone health, hair loss, or cold prevention. More research is needed.
Is this the same as eating mulberry fruit?
No. Mulberry leaf powder is a concentrated supplement and is less studied than mulberry as a food. The safety profile is different, which is why we're cautious.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if White Mulberry is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

White Mulberry label
Go deeper

The Full Monographs Behind White Mulberry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph →
Sources

Sources & How We Checked

White Mulberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Mulberry 6 references
  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed

See these in context on the White Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team