FDA-filed SPL labeling · retrieved through openFDA

Risperidone

Risperidone is an atypical antipsychotic used to treat schizophrenia, bipolar mania, and irritability related to autism.

Brand names Risperdal M-TAB Orally Disintegrating TabletsRisperdal Oral SolutionRisperdal TabletsRisperdalPerseris +5 more
Drug class Atypical Antipsychotic
Rx Forms 4 Routes Oral · Subcutaneous · Intramuscular
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 73 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

At a glance
Linked label effectiveMay 28, 2026
Clinical labels in scope 73
AvailabilityRx
Earliest approval/marketing year 1993
FDA-listed product records 565
Boxed warningYes
How we combine label and product data →
No current FDA shortage listed · checked Sep 19, 2026
Other forms & routes:
Risperidone at a glance The quick version — the full detail is in the Patient Information Guide below.
💊
HelloPharmacist Editorial Team Bottom Line
Risperidone is a well-established medication for schizophrenia, bipolar mania, and autism-related irritability, but it requires careful monitoring — especially for weight, blood sugar, and movement-related side effects. It is never appropriate for elderly patients with dementia. Work closely with your prescriber to find the right dose and watch for any changes that need attention.
⚠️ FDA Boxed Warning — the FDA’s strongest safety alert

Important safety warning: Risperidone should NOT be used in elderly patients who have dementia-related psychosis. Studies have shown that older adults with dementia who take antipsychotic drugs like risperidone have a significantly higher risk of death compared to those who take a placebo. There is also an increased risk of stroke in this group. If an elderly loved one has dementia, make sure their care team knows this drug is not approved or safe for that condition.

Read the full warning on DailyMed →

📖 Risperidone: Patient Information Guide

A plain-language walkthrough of Risperidone — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.

🎯What it's used for

Risperidone is an atypical antipsychotic approved to treat several serious psychiatric conditions:

  • Schizophrenia — in adults and adolescents ages 13 to 17
  • Acute manic or mixed episodes in Bipolar I Disorder — in adults, and children/adolescents ages 10 to 17; can be used alone or with lithium or valproate
  • Irritability associated with autistic disorder — including aggression, self-injury, temper tantrums, and rapid mood changes — in children and adolescents ages 5 to 17
⚙️How it works

Risperidone works by blocking specific receptors in the brain — particularly dopamine D2 receptors (involved in mood, perception, and movement) and serotonin 5HT2 receptors (involved in emotion regulation). Overactivity in these pathways is linked to symptoms like hallucinations, delusions, and extreme mood swings. By dialing down these signals, risperidone helps bring those symptoms under control.

The body converts risperidone into an active metabolite (breakdown product) called 9-hydroxyrisperidone. Both the original drug and this metabolite are active, and together they produce the full therapeutic effect. Risperidone also binds to other receptors — including histamine and adrenaline-related ones — which accounts for some of its other effects, like drowsiness or blood pressure changes.

💊How it's taken

Risperidone is taken by mouth and is available as a regular tablet, an orally disintegrating tablet (dissolves on your tongue without water), and a liquid solution. It may be taken once or twice daily depending on the condition being treated and your prescriber's guidance. Food does not affect how it is absorbed, so you can take it with or without a meal.

  • Doses are started low and gradually increased to reduce side effects
  • People with kidney or liver problems typically start at a lower dose
  • Always follow your prescriber's exact instructions — do not adjust your dose on your own
🤒Side effects — in detail

The most commonly reported side effects in clinical trials include:

  • Drowsiness or sedation
  • Dizziness
  • Weight gain and increased appetite
  • Nausea, vomiting, or stomach discomfort
  • Tremor, muscle stiffness, or slow movement (parkinsonism)
  • Restlessness or an inability to sit still (akathisia)
  • Muscle spasms or abnormal postures (dystonia)
  • Blurred vision
  • Nasal congestion or upper respiratory infections
  • Dry mouth or increased saliva

Serious reactions — like high fever with muscle rigidity, uncontrolled repetitive movements, signs of high blood sugar, or a sudden painful erection — require immediate medical attention. Don't wait to call your doctor if these occur.

⚠️Warnings & precautions
  • Elderly patients with dementia: Risperidone is NOT approved for dementia-related psychosis and carries a significantly increased risk of death and stroke in this population.
  • Neuroleptic Malignant Syndrome (NMS): A rare but life-threatening reaction involving high fever, severe muscle stiffness, confusion, and irregular heartbeat. Requires immediate discontinuation of the drug and emergency care.
  • Tardive dyskinesia: Uncontrolled, repetitive muscle movements — especially of the face — that can develop and may become permanent. Your doctor may stop the medication if this occurs.
  • Metabolic changes: Risperidone can cause weight gain, high blood sugar (potentially leading to diabetes), and abnormal cholesterol levels — all of which raise long-term heart and circulation risk.
  • Low white blood cell count: Can increase infection risk. Blood counts should be monitored in people with a history of this problem.
  • Orthostatic hypotension: A sudden drop in blood pressure when standing, which can cause fainting — especially when starting the medication.
  • Seizures: Use with extra caution if you have a history of seizures.
  • Elevated prolactin: Risperidone raises prolactin (a hormone) levels, which can persist with long-term use and may cause side effects related to reproductive hormones.
🔀What it interacts with

Risperidone's levels in the blood can be significantly affected by other medications, so your prescriber may need to adjust your dose:

  • Carbamazepine and other enzyme inducers — speed up risperidone's breakdown, lowering its levels; dose may need to be increased (up to double the usual dose)
  • Fluoxetine and paroxetine (CYP2D6 inhibitors) — slow risperidone's breakdown, raising its blood levels; dose may need to be reduced
  • Ranitidine, cimetidine, erythromycin, amitriptyline — have small effects on risperidone levels that generally don't require dose changes
  • Lithium and valproate — risperidone does not significantly affect their levels; often used together intentionally for bipolar mania

This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.

📋Before taking it
  • Allergy: Do not take if you are allergic to risperidone, paliperidone, or any ingredient in the oral solution — serious allergic reactions including anaphylaxis have been reported
  • Dementia: Risperidone is not appropriate for elderly patients with dementia-related psychosis due to a serious increased risk of death and stroke
  • Pregnancy: Babies born to mothers who took antipsychotics in the third trimester may have muscle stiffness or withdrawal symptoms. A pregnancy registry exists — ask your healthcare provider about it
  • Kidney or liver impairment: A lower starting dose is recommended; dose increases should be made more slowly
  • Diabetes or high blood sugar risk: Risperidone can raise blood sugar; regular glucose monitoring is advised
  • Seizure history: Use with caution; risperidone may lower the threshold for seizures
  • Driving and machinery: Risperidone can impair alertness and coordination — use caution until you know how it affects you
  • Children: Approved for specific age groups depending on the condition; doses are lower and carefully titrated by weight and age
🚑If you take too much

Taking too much risperidone can cause drowsiness, sedation, a fast heartbeat, low blood pressure, and movement-related symptoms. In some cases, overdose has been associated with abnormal heart rhythms, seizures, and electrolyte imbalances. There is no specific antidote — if you suspect an overdose, call Poison Control immediately at 1-800-222-1222 or go to the nearest emergency room.

📡Pharmacodynamics — effects in the body

Risperidone strongly blocks several receptor types in the brain and body, including serotonin 5HT2, dopamine D2, and certain adrenaline (alpha-adrenergic) and histamine receptors. Blocking dopamine D2 receptors is linked to its antipsychotic effects; blocking serotonin and histamine receptors contributes to its effects on mood and sedation. It does not significantly affect muscarinic (acetylcholine) receptors, which distinguishes it from older antipsychotics and means fewer anticholinergic side effects like dry mouth and urinary retention.

🔬Pharmacokinetics — how your body processes it

Risperidone is well absorbed after oral dosing — about 70% reaches the bloodstream — and food does not change this. It peaks in the blood within about an hour and is extensively processed by the liver into its active metabolite, 9-hydroxyrisperidone, mainly through a liver enzyme called CYP2D6. People who process this enzyme quickly (extensive metabolizers) reach stable drug levels in about one day, while those who process it slowly (poor metabolizers) may take up to five days. The drug is largely protein-bound in the blood and is cleared through the liver, making dose adjustments important for people with liver or kidney problems.

📦How to store it

stored at controlled room temperature 15 °C to 25 °C (59 °F to 77 °F). Protect from light and moisture. Protect from light and freezing.

📄 Written from Risperidone’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →

199

Supplements & herbs that interact with Risperidone

199 supplements and herbal products have documented interactions with Risperidone in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 11
  • Moderate · 147
  • Minor · 41
Every supplement checked against Risperidone — ranked by severity The full interaction hub: 11 major · 147 moderate · 41 minor · every one linked to its full report. Check Risperidone against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

🩺 Pharmacist Counseling Corner

Quick, plain-English answers to the questions patients ask most about Risperidone — the kind of thing our pharmacy team would talk through with you at the counter.

What is risperidone actually used for — my doctor mentioned a few different things.
Risperidone is approved for three main uses: treating schizophrenia, managing acute manic or mixed episodes in Bipolar I Disorder, and reducing irritability — things like aggression, self-injury, or severe temper outbursts — in children and teens with autism. It works across a fairly broad range of conditions because it targets chemical signals in the brain involved in mood, perception, and emotional regulation. Your doctor chose it based on your specific situation, so if you're unsure why it was prescribed for you, that's a great question to ask them directly.
Will I feel drowsy or like a 'zombie' on this medication?
Drowsiness and sedation are among the more common side effects, especially when you first start or when your dose increases. For most people, this tends to ease up as your body adjusts. Taking your dose in the evening can help. That said, until you know how risperidone affects you, be careful driving or operating machinery. If the drowsiness feels unmanageable after a few weeks, let your prescriber know — they may be able to adjust the timing or dose.
I heard this medication can cause weight gain. Is that true?
Yes, weight gain is a real and well-documented side effect with risperidone. It can also affect your blood sugar and cholesterol over time. That doesn't mean you're helpless against it — staying active, watching what you eat, and keeping up with your regular check-ups (including blood sugar and cholesterol monitoring) can make a significant difference. Your prescriber or pharmacist can talk through strategies with you, and your doctor should be tracking your weight and labs regularly while you're on this medication.
Are there any signs I should call my doctor about right away?
Absolutely — a few things warrant a prompt call or emergency care. If you develop a high fever, severe muscle stiffness, or confusion, get help immediately — this could be a rare but serious reaction called neuroleptic malignant syndrome. Also watch for uncontrolled or repetitive muscle movements, especially in your face or tongue, which can signal a condition called tardive dyskinesia. Feeling faint when you stand up, signs of high blood sugar like extreme thirst or frequent urination, or any signs of infection with an unexplained fever should also prompt a call to your doctor.
Can I take risperidone with my other medications?
Some medications do interact with risperidone in ways that matter. For example, antidepressants like fluoxetine (Prozac) or paroxetine (Paxil) can raise risperidone levels in your blood, so your dose might need to be adjusted. On the flip side, the seizure medication carbamazepine can lower risperidone levels, potentially making it less effective. Always tell your doctor and pharmacist about every medication you take — prescription, over-the-counter, and supplements — so they can check for interactions and adjust your dose if needed.
Is it safe to take risperidone during pregnancy?
This is something to discuss honestly with your doctor. Babies born to mothers who took antipsychotics like risperidone during the third trimester can sometimes have muscle stiffness or withdrawal-like symptoms after birth. That said, untreated schizophrenia or severe bipolar disorder also carries real risks during pregnancy. It's not a simple either/or — your doctor needs to weigh the risks and benefits for your specific situation. There is also a national pregnancy registry for this medication that your provider can enroll you in to help track outcomes.
Is Risperidone available over the counter?
Risperidone is dispensed by prescription according to its FDA labeling, so it isn't sold over the counter. Your prescriber and pharmacist will determine if it's appropriate for you.
When was Risperidone first available?
Risperidone has been available in the United States since at least 1993, based on FDA approval history (Drugs@FDA) and product marketing records.
Who makes Risperidone?
Risperidone is supplied by 76 manufacturers listed in the FDA NDC Directory, including Janssen Pharmaceuticals, Inc., Remedyrepack Inc., AvKARE.

💬 Answers drafted from Risperidone’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →

🧰 Keep exploring

💊 How Risperidone comes

Risperidone is available in 4 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Orally disintegrating tablet

By mouth
Brands Risperdal M-tab
Available strengths 6 strengths
98 FDA-listed product records

Oral solution

By mouth
Brands Risperdal
Available strengths 1 strength
34 FDA-listed product records

📊 Risperidone across the U.S. market

How Risperidone appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

4
Dose forms
76
Manufacturers
8
Brand names
565
FDA-listed product records
1993
First marketed

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Kit (46) · Powder (18) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Janssen Pharmaceuticals, Inc.11%
Remedyrepack Inc.9%
AvKARE7%
Major Pharmaceuticals5%
Amneal Pharmaceuticals NY LLC5%
Teva Pharmaceuticals USA, Inc.4%
Other makers60%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

📈 How widely Risperidone is used

A general measure of how commonly Risperidone is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Risperidone is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

3,411,596
Medicaid prescriptions filled (Q1–Q4 2025)
$332.2M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Risperidone prescribed? Of the 1,596 medications we measure, Risperidone ranks #61 by Medicaid prescriptions — more than 96% of them.

Where Risperidone ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Risperidone product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 1 mg oral tablet is the most-dispensed Risperidone product — about 28% of these Medicaid prescriptions.

risperidone 1 MG Oral Tablet Most dispensed

939,462 Medicaid prescriptions (Q1–Q4 2025) 28% of Risperidone prescriptions shown $9.7M gross reimbursement (before rebates) ≈ $10 per prescription (gross)

Summed across the 14 of 98 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312830

risperidone 0.5 MG Oral Tablet

688,891 Medicaid prescriptions (Q1–Q4 2025) 20% of Risperidone prescriptions shown $6.5M gross reimbursement (before rebates) ≈ $9.46 per prescription (gross)

Summed across the 13 of 75 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312829

risperidone 2 MG Oral Tablet

618,805 Medicaid prescriptions (Q1–Q4 2025) 18% of Risperidone prescriptions shown $6.8M gross reimbursement (before rebates) ≈ $11 per prescription (gross)

Summed across the 11 of 101 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312831

risperidone 3 MG Oral Tablet

336,550 Medicaid prescriptions (Q1–Q4 2025) 10% of Risperidone prescriptions shown $3.8M gross reimbursement (before rebates) ≈ $11 per prescription (gross)

Summed across the 10 of 70 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312832

risperidone 0.25 MG Oral Tablet

268,578 Medicaid prescriptions (Q1–Q4 2025) 8% of Risperidone prescriptions shown $2.5M gross reimbursement (before rebates) ≈ $9.20 per prescription (gross)

Summed across the 9 of 66 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312828

risperidone 4 MG Oral Tablet

198,553 Medicaid prescriptions (Q1–Q4 2025) 6% of Risperidone prescriptions shown $2.4M gross reimbursement (before rebates) ≈ $12 per prescription (gross)

Summed across the 10 of 72 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 314211

risperidone 1 MG/ML Oral Solution

165,780 Medicaid prescriptions (Q1–Q4 2025) 5% of Risperidone prescriptions shown $7.3M gross reimbursement (before rebates) ≈ $44 per prescription (gross)

Summed across the 5 of 30 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 199387

0.35 ML risperidone 357 MG/ML Prefilled Syringe

24,582 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $76.3M gross reimbursement (before rebates) ≈ $3,103 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636041

risperidone 50 MG Injection

24,064 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $35.8M gross reimbursement (before rebates) ≈ $1,489 per prescription (gross)

Summed across the 2 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 402012

risperidone 0.5 MG Disintegrating Oral Tablet

22,358 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $1.1M gross reimbursement (before rebates) ≈ $47 per prescription (gross)

Summed across the 3 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 403825

risperidone 1 MG Disintegrating Oral Tablet

21,710 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $1.2M gross reimbursement (before rebates) ≈ $57 per prescription (gross)

Summed across the 3 of 20 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 401953

0.28 ML risperidone 357 MG/ML Prefilled Syringe

19,969 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $49.9M gross reimbursement (before rebates) ≈ $2,500 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636033

risperidone 2 MG Disintegrating Oral Tablet

13,489 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $811,947 gross reimbursement (before rebates) ≈ $60 per prescription (gross)

Summed across the 2 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 401954

risperidone 25 MG Injection

10,970 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $8.2M gross reimbursement (before rebates) ≈ $748 per prescription (gross)

Summed across the 2 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 402010

risperidone 37.5 MG Injection

8,315 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $9.7M gross reimbursement (before rebates) ≈ $1,170 per prescription (gross)

Summed across the 2 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 402011

risperidone 3 MG Disintegrating Oral Tablet

6,274 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $462,581 gross reimbursement (before rebates) ≈ $74 per prescription (gross)

Summed across the 2 of 18 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 616698

0.7 ML risperidone 357 MG/ML Prefilled Syringe

5,965 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $37.8M gross reimbursement (before rebates) ≈ $6,344 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636047

risperidone 0.25 MG Disintegrating Oral Tablet

5,589 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $578,405 gross reimbursement (before rebates) ≈ $103 per prescription (gross)

Summed across the 1 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 645037

0.8 ML risperidone 150 MG/ML Prefilled Syringe

5,495 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $14.9M gross reimbursement (before rebates) ≈ $2,714 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2055667

0.21 ML risperidone 357 MG/ML Prefilled Syringe

5,492 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $10.4M gross reimbursement (before rebates) ≈ $1,886 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636051

0.14 ML risperidone 357 MG/ML Prefilled Syringe

5,145 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $6.6M gross reimbursement (before rebates) ≈ $1,278 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636049

0.56 ML risperidone 357 MG/ML Prefilled Syringe

4,703 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $23.6M gross reimbursement (before rebates) ≈ $5,022 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636045

risperidone 4 MG Disintegrating Oral Tablet

4,671 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $505,748 gross reimbursement (before rebates) ≈ $108 per prescription (gross)

Summed across the 2 of 16 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 616705

0.42 ML risperidone 357 MG/ML Prefilled Syringe

2,567 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $9.9M gross reimbursement (before rebates) ≈ $3,861 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2636043

0.6 ML risperidone 150 MG/ML Prefilled Syringe

2,403 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $5M gross reimbursement (before rebates) ≈ $2,076 per prescription (gross)

Summed across the 1 of 4 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 2055675

risperidone 12.5 MG Injection

1,216 Medicaid prescriptions (Q1–Q4 2025) <1% of Risperidone prescriptions shown $411,733 gross reimbursement (before rebates) ≈ $339 per prescription (gross)

Summed across the 2 of 6 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 706822

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Risperidone, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 102 of 670 listed Risperidone NDCs with Medicaid activity.

🔍 Compare Risperidone products

A representative set of FDA-listed product records for Risperidone — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 200 of 565 products — FDA National Drug Code Directory. See every product, package size and price: browse all 565 Risperidone NDCs →

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Risperidone RxCUI 35636 5 dose forms · 27 strengths
  1. Dose form (SCDF) Disintegrating Oral Tablet RxCUI 402348 In current FDA listings
    Clinical drug / strength (SCD) 0.25 MG RxCUI 645037 0.5 MG RxCUI 403825 1 MG RxCUI 401953 2 MG RxCUI 401954 3 MG RxCUI 616698 4 MG RxCUI 616705
  2. Dose form (SCDF) Injection RxCUI 1743574 In current FDA listings
    Clinical drug / strength (SCD) 12.5 MG RxCUI 706822 25 MG RxCUI 402010 37.5 MG RxCUI 402011 50 MG RxCUI 402012
  3. Dose form (SCDF) Oral Solution RxCUI 373790 In current FDA listings
    Clinical drug / strength (SCD) 1 MG/ML RxCUI 199387
  4. Dose form (SCDF) Oral Tablet RxCUI 373791 In current FDA listings
    Clinical drug / strength (SCD) 0.25 MG RxCUI 312828 0.5 MG RxCUI 312829 1 MG RxCUI 312830 2 MG RxCUI 312831 3 MG RxCUI 312832 4 MG RxCUI 314211 6 MG RxCUI 153791
  5. Dose form (SCDF) Prefilled Syringe RxCUI 2055666 No current FDA listing

Look up RxCUI 35636 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

🏷️ Sold under these brand names

Risperdal M-TAB Orally Disintegrating Tablets Risperdal Oral Solution Risperdal Tablets Risperdal Perseris Uzedy Rykindo Risperdal M-tab Risperdal Consta Rykindo extended-release microspheres

🏭 Manufacturers & labelers

Janssen Pharmaceuticals, Inc. 57 Remedyrepack Inc. 44 AvKARE 35 Major Pharmaceuticals 24 Amneal Pharmaceuticals NY LLC 24 Teva Pharmaceuticals USA, Inc. 21 Bryant Ranch Prepack 21 Solco Healthcare US, LLC 18 Zydus Lifesciences Limited 15 Zydus Pharmaceuticals USA Inc. 15 Ajanta Pharma USA Inc. 12 Torrent Pharmaceuticals Limited 12 Par Health USA, LLC 12 Par Pharmaceutical, Inc. 12 American Health Packaging 12 Jubilant Cadista Pharmacuticals Inc. 11 Amneal Pharmaceuticals LLC 11 Dr. Reddy's Laboratories Limited 11 Jubilant Cadista Pharmaceuticals Inc. 10 NCS HealthCare of KY, LLC dba Vangard Labs 10 Zydus Pharmaceuticals (USA) Inc. 9 A-S Medication Solutions 9 Teva Pharmaceuticals, Inc. 8 Aphena Pharma Solutions - Tennessee, LLC 8

…and 16 more on the FDA NDC directory.

RxNorm drug class

Risperidone belongs to the Atypical Antipsychotic class.

Pharmacologic class Atypical Antipsychotic
Drug family (ATC) Other antipsychotics

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

🔬 Where this comes from

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective May 28, 2026
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Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Risperidone.
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Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
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Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Risperidone after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
73
NDC products indexed
565
Distinct labelers/manufacturers represented
76
Linked representative label
Janssen Pharmaceuticals, Inc.
Linked label effective
May 28, 2026
Composite sections available
27
Linked SPL Set ID
7e117c7e-02fc-4343-92a1-230061dfc5e0
Linked SPL Document ID
408e48a3-35fc-49e1-8e01-44305d9083a4
Open the linked representative label on DailyMed ↗

How we combine label and product data

HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 73 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.

For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Janssen Pharmaceuticals, Inc. is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.

This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.