Pralsetinib

Name: Pralsetinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions

Also sold as: Gavreto Gavreto®

About Pralsetinib

Pralsetinib is used to treat a certain type of non small-cell lung cancer (NSCLC) in adults that has spread to other parts of the body. It is also used to treat a certain type of thyroid cancer in adults and children 12 years of age and older that is getting worse or that has spread to other parts of the body. Pralseti… Read the full Pralsetinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Cyclosporine Injection Cyclosporine Ophthalmic Ketoconazole Topical Lenacapavir Injection Lenacapavir Oral Letermovir Injection

7 Major 1 Moderate

All (8) Major (7) Moderate (1)

Moderate

Pralsetinib Levothyroxine Ermeza Increased risk of hypothyroidism Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.