Tepotinib

Name: Tepotinib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

13 interactions 2 explained in plain English

Also sold as: Tepmetko Tepmetko®

About Tepotinib

Tepotinib is used to treat a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the body in adults. Tepotinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the… Read the full Tepotinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Relugolix Cyclosporine Injection Cyclosporine Ophthalmic Dabigatran Dabigatran Etexilate

1 Contraindicated 11 Major 1 Moderate

All (13) Contraindicated (1) Major (11) Moderate (1)

Moderate

Tepotinib Levothyroxine Ermeza Increased risk of hypothyroidism Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.