Valproic Acid
35 interactions 2 explained in plain EnglishValproic acid is an anticonvulsant used to treat seizures, mania in bipolar disorder, and prevent migraine headaches. Read the full Valproic Acid drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Valproic Acid Amitriptyline Elavil Explained Increased amitriptyline exposure Details Valproic Acid Acyclovir Avaclyr Decreased valproic acid plasma concentrations and potential increased seizure activity Details Valproic Acid Acyclovir Injection Avaclyr Decreased valproic acid plasma concentrations and potential increased seizure activity Details Valproic Acid Acyclovir Ophthalmic Avaclyr Decreased valproic acid plasma concentrations and potential increased seizure activity Details Valproic Acid Acyclovir Topical Zovirax Decreased valproic acid plasma concentrations and potential increased seizure activity Details Valproic Acid Cholestyramine Resin Locholest® Decreased serum valproic acid concentrations Details Valproic Acid Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Valproic Acid Mefloquine Lariam® Loss of seizure control Details Valproic Acid Nimodipine Nimotop Nimodipine toxicity (dizziness, headache, flushing, peripheral edema) DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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