Vandetanib

Name: Vandetanib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

74 interactions 6 explained in plain English

Also sold as: Caprelsa Caprelsa®

About Vandetanib

Vandetanib is used to treat a certain type of thyroid cancer that cannot be treated by surgery or that has spread to other parts of the body. Vandetanib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or… Read the full Vandetanib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketoconazole Topical Colchicine Ivabradine Oxaliplatin Injection Hydroxychloroquine Amisulpride Injection

2 Contraindicated 71 Major 1 Moderate

All (74) Contraindicated (2) Major (71) Moderate (1)

Contraindicated

Vandetanib Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details Vandetanib Ketoconazole Topical Extina® Foam Increased vandetanib exposure and an increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.