Drug & supplement interaction

Agrimony + Benzocaine/Menthol

Benzocaine/Menthol brand names: Chloraseptic Sore Throat Lozenges, Anbesol.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Agrimony and Benzocaine/Menthol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Agrimony and Benzocaine/Menthol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Benzocaine/Menthol and Agrimony in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Agrimony safety at a glance

Agrimony overall Use caution Generally used in food-like amounts in tea, but human safety data are limited, so use with care.
Pregnancy Possibly Unsafe When used orally due to possible effects on the menstrual cycle. Read the full pregnancy detail
Breastfeeding Avoid Safety while breastfeeding has not been studied, so avoid it to be cautious.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Benzocaine/Menthol and Agrimony? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Benzocaine/Menthol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Benzocaine/Menthol is filed under 2 classifications — topical drugs, oral drugs. Agrimony has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Benzocaine/Menthol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Agrimony Does Interact With Other Medications

Agrimony has 86 moderate known drug interactions in our database — Benzocaine/Menthol isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Agrimony

Covers the 2,830 medications we’ve checked against Agrimony. Pick one to open its full report.

Special populations

Agrimony in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used orally due to possible effects on the menstrual cycle.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Benzocaine/Menthol

This page covers Agrimony only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Benzocaine/Menthol page lists 20 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), Dimethylsulfoxide (dmso) (moderate), European Mandrake (moderate) and Glucomannan (moderate).

By severity: 1 major · 9 moderate · 10 minor.

Open the Benzocaine/Menthol interaction page

One more smart check

Taking Agrimony as Part of a Dietary Supplement Product? Check It for Interactions

We hold 75 real supplement products containing Agrimony, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Agrimony. Even though Agrimony itself has no known interaction with Benzocaine/Menthol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Agrimony and Benzocaine/Menthol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Agrimony
Top half

#543 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Benzocaine/Menthol
Top half

#1,314 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Agrimony reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Agrimony and Benzocaine/Menthol records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Agrimony

What is Agrimony?

Agrimony
  • Sore throat and mouth irritation
  • Mild diarrhea and digestive upset
  • Minor wounds and skin irritation
  • Gallbladder and liver complaints
  • Blood sugar support

Agrimony is a traditional European herb rich in tannins that has long been used for sore throats, mild diarrhea, and minor skin problems. Good-quality human studies are very limited, so its benefits remain unproven. If you choose to try it, use it short-term, follow the product label, and check with your pharmacist or doctor first.

Agrimonia eupatoria · Rosaceae · Dried above-ground parts (leaves, stems, flowers) and seeds · Tea, tincture, liquid extract, capsules, gargle or mouth rinse, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Agrimony is a good idea for someone in your situation. Here is what our Agrimony record says about it on its own.

Agrimony: dosing

There is no well-established, standardized dose for agrimony. Traditional use has been mainly as a tea made from the dried herb, or as a tincture or liquid extract.If you choose to use an agrimony product, follow the directions on the label and do not exceed the recommended amount.

From our Agrimony monograph — the full record covers uses, side effects and every documented interaction.

Read the full Agrimony monograph & all interactions
Keep checking

Other Drugs & Agrimony

Browse every other medication we’ve checked against Agrimony — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Agrimony page.

No interaction 2,743 drugs checked — show the list
Evidence & sources

Agrimony References

The 4 references that drive our Agrimony monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gray AM, Flatt PR. Actions of the traditional anti-diabetic plant, Agrimony eupatoria (agrimony): effects on hyperglycaemia, cellular glucose metabolism and insulin secretion. Br J Nutr 1998;80:109-14.
  4. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Agrimony and Benzocaine/Menthol Together: Common Questions

Is it safe to take Agrimony with Benzocaine/Menthol?
We do not list a known interaction between Agrimony and Benzocaine/Menthol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Agrimony and Benzocaine/Menthol combination checked?
Interactions in our licensed database are recorded against drug classes. Benzocaine/Menthol is filed under 2 classifications, and Agrimony has documented interactions with 1 drug class — none of Benzocaine/Menthol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Agrimony interact with any other medications?
Yes. Agrimony has 86 documented drug interactions in our database — Benzocaine/Menthol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Benzocaine/Menthol interact with any supplements?
Yes. Benzocaine/Menthol has documented interactions with 20 supplements in our database — Agrimony is not one of them. The Benzocaine/Menthol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Benzocaine/Menthol and Agrimony?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.