Agrimony - Toujeo Solostar (Insulin Glargine Recombinant) Interaction
Herbal: Agrimony
Also Known As: Agrimonia eupatoria, Agrimone, Agrimonia, Church Steeples, Churchsteeples, Cockeburr, Cocklebur, Common Agrimony, Fragrant Agrimony, Francormier, Herba Agrimoniae, Philanthropos, Soubeirette, Sticklewort
Drug: Insulin Glargine Recombinant
Brand names:
Toujeo Solostar
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
Insulin Glargine Recombinant is classified as belonging to the following category: Antidiabetes Drugs
Theoretically, taking agrimony with antidiabetes drugs might increase the risk of hypoglycemia.
Agrimony has demonstrated hypoglycemic effects in animal research.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Gray AM, Flatt PR. Actions of the traditional anti-diabetic plant, Agrimony eupatoria (agrimony): effects on hyperglycaemia, cellular glucose metabolism and insulin secretion. Br J Nutr 1998;80:109-14.
- Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4.
Agrimony Overview
Agrimony (Agrimonia eupatoria) is a perennial herb with yellow flowers and serrated leaves, found in Europe, Asia, and parts of Africa. Its dried above-ground parts and seeds are used in herbal preparations. These contain 4% to 10% condensed tannins like agrimoniin, ellagitannin, and gallotannin, as well as flavonoids, terpenoids, phenolic acids, and coumarins. Notably, luteolin-7-glucuronide is the major flavonoid. Agrimony provides vitamins C, thiamine, and K, along with other beneficial compounds. Agrimony has been traditionally used in herbal medicine to assist in treating bleeding, diabetes, sore throat, as well as cardiovascular, gallbladder, gastrointestinal, kidney, liver, and skin conditions.
Agrimony - More Interactions
Agrimony interacts with 84 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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