Drug & supplement interaction

Agrimony + Calcipotriene

Calcipotriene brand name: Dovonex.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Agrimony and Calcipotriene in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Agrimony and Calcipotriene

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Calcipotriene and Agrimony in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Agrimony safety at a glance

Agrimony overall Use caution Generally used in food-like amounts in tea, but human safety data are limited, so use with care.

Pregnancy Possibly Unsafe When used orally due to possible effects on the menstrual cycle. Read the full pregnancy detail

Breastfeeding Avoid Safety while breastfeeding has not been studied, so avoid it to be cautious.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Calcipotriene and Agrimony? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Calcipotriene

Interactions in our licensed database are recorded against drug classes, not just single drug names. Calcipotriene is filed under 2 classifications — including topical drugs. Agrimony has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Calcipotriene’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Agrimony Does Interact With Other Medications

Agrimony has 86 moderate known drug interactions in our database — Calcipotriene isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Calcipotriene)

Taking anything else?

Check Another of Your Medications Against Agrimony

Covers the 2,830 medications we’ve checked against Agrimony. Pick one to open its full report.

What to actually watch for

What Calcipotriene’s Own FDA Label Lists

This is not an interaction — none of it involves Agrimony. These are the most notable effects listed in the ADVERSE REACTIONS section of Calcipotriene’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both.

Itching mentioned in 5.4% of FDA reports for Calcipotriene
A skin rash mentioned in 5.0% of FDA reports for Calcipotriene

From the ADVERSE REACTIONS section of the FDA label for Calcipotriene. Read the label on DailyMed › Where a percentage is shown, it is the share of 6,726 voluntary FDA FAERS reports for Calcipotriene that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Agrimony’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Agrimony side to compare — that is a limit of the record, not a statement that Agrimony has no side effects.

Special populations

Agrimony in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When used orally due to possible effects on the menstrual cycle.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Calcipotriene

This page covers Agrimony only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Calcipotriene page lists 5 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Calcium (moderate), Dimethylsulfoxide (dmso) (moderate), Turpentine Oil (moderate), Vitamin D (moderate) and Alchemilla (minor).

By severity: 4 moderate · 1 minor.

From our pharmacist’s overview on the Calcipotriene page

“Calcipotriene (Dovonex) is a psoriasis cream built around a lab-made form of vitamin D, and that is exactly why its short supplement list, just five ingredients, centers on calcium. Enough of the drug can soak through the skin to raise blood calcium, so taking vitamin D or calcium supplements alongside it can theoretically stack onto t…”

Reviewed by 2 · Jul 18, 2026

Open the Calcipotriene interaction page

One more smart check

Taking Agrimony as Part of a Dietary Supplement Product? Check It for Interactions

We hold 75 real supplement products containing Agrimony, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Agrimony. Even though Agrimony itself has no known interaction with Calcipotriene, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Agrimony and Calcipotriene Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Agrimony

Top half

#552 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Calcipotriene

Steady interest

#1,844 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Agrimony reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Agrimony and Calcipotriene records this page draws on were last updated July 11, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Agrimony

What is Agrimony?

Sore throat and mouth irritation
Mild diarrhea and digestive upset
Minor wounds and skin irritation
Gallbladder and liver complaints
Blood sugar support

Agrimony is a traditional European herb rich in tannins that has long been used for sore throats, mild diarrhea, and minor skin problems. Good-quality human studies are very limited, so its benefits remain unproven. If you choose to try it, use it short-term, follow the product label, and check with your pharmacist or doctor first.

Agrimonia eupatoria · Rosaceae · Dried above-ground parts (leaves, stems, flowers) and seeds · Tea, tincture, liquid extract, capsules, gargle or mouth rinse, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Agrimony is a good idea for someone in your situation. Here is what our Agrimony record says about it on its own.

Agrimony: dosing

There is no well-established, standardized dose for agrimony. Traditional use has been mainly as a tea made from the dried herb, or as a tincture or liquid extract.If you choose to use an agrimony product, follow the directions on the label and do not exceed the recommended amount.

From our Agrimony monograph — the full record covers uses, side effects and every documented interaction.

Read the full Agrimony monograph & all interactions

Medication

About Calcipotriene Topical

What Is Calcipotriene Topical Used For?

Brand name: Dovonex

Calcipotriene is applied directly to the skin to treat plaque psoriasis — the common form of psoriasis that causes raised, scaly patches. Calcipotriene foam (brands include Sorilux) is approved for plaque psoriasis of the scalp and body in adults and children 4 years and older.

Pellix Topical Solution is applied specifically to scalp psoriasis lesions. Calcitrene ointment (and related creams) is also used for plaque psoriasis, but should not be applied to the face.

Most-Reported Side Effects for Calcipotriene

From FAERS, the FDA’s public side-effect reporting system (6,726 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Psoriasis 1,364 reports

Diarrhea 433 reports

Headache 363 reports

Pruritus 360 reports

Nausea 359 reports

See full Calcipotriene Topical drug information

Keep checking

Other Drugs & Agrimony

Browse every other medication we’ve checked against Agrimony — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

86Moderate

0Minor

2,743No known interaction

86 Moderate 2,743 No interaction

Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Agrimony page.

No interaction 2,743 drugs checked — show the list

We also checked Agrimony against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Agrimony list.

See the full Agrimony interactions page

See every supplement checked against Calcipotriene, ranked by severity

Evidence & sources

Agrimony References

The 4 references that drive our Agrimony monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Gray AM, Flatt PR. Actions of the traditional anti-diabetic plant, Agrimony eupatoria (agrimony): effects on hyperglycaemia, cellular glucose metabolism and insulin secretion. Br J Nutr 1998;80:109-14.
Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990;33:462-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Agrimony and Calcipotriene Together: Common Questions

Is it safe to take Agrimony with Calcipotriene?

We do not list a known interaction between Agrimony and Calcipotriene. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

How was the Agrimony and Calcipotriene combination checked?

Interactions in our licensed database are recorded against drug classes. Calcipotriene is filed under 2 classifications, and Agrimony has documented interactions with 1 drug class — none of Calcipotriene's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Agrimony interact with any other medications?

Yes. Agrimony has 86 documented drug interactions in our database — Calcipotriene is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Calcipotriene interact with any supplements?

Yes. Calcipotriene has documented interactions with 5 supplements in our database — Agrimony is not one of them. The Calcipotriene interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Agrimony monograph Uses, safety profile, and every drug interaction in one place Calcipotriene Topical drug information The full plain-English guide to this medication Calcipotriene supplement interactions Every supplement checked against Calcipotriene, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Calcipotriene and Agrimony?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.