Drug & supplement interaction

Dendrobium + Brentuximab Vedotin

Brentuximab Vedotin brand name: Adcetris.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Dendrobium and Brentuximab Vedotin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Dendrobium and Brentuximab Vedotin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Brentuximab Vedotin and Dendrobium in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dendrobium safety at a glance

Dendrobium overall Use caution Generally used in traditional medicine, but modern safety data in people is limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Brentuximab Vedotin and Dendrobium? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Brentuximab Vedotin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Brentuximab Vedotin is filed under a single classification — cytochrome p450 3a4 (cyp3a4) substrates. Dendrobium has documented interactions with 3 drug classes — the most serious being anticonvulsants (moderate), seizure threshold lowering drugs (moderate) and antihypertensive drugs (minor) — and none of Brentuximab Vedotin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Dendrobium Does Interact With Other Medications

Dendrobium has 461 moderate, 148 minor known drug interactions in our database — Brentuximab Vedotin isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Dendrobium

Covers the 2,830 medications we’ve checked against Dendrobium. Pick one to open its full report.

What to actually watch for

What Dendrobium Itself Has Been Linked To

This is not an interaction — nothing below involves Brentuximab Vedotin. It is the side-effect record for Dendrobium on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Dendrobium, this list is the first place to look.

  • Anxiety or restlessness / Trouble sleeping / Stomach upset Additional detail

    “Orally, a thorough evaluation of safety outcomes has not been conducted. The only reports of adverse effects, including jitteriness, upset stomach, and insomnia, are related to the use of a combination product that was found to contain amphetamine-like ingredients. It is unclear whether any of these effects can be attributed to dendrobium.”

    Dendrobium · Natural Medicines adverse-effect record, reported in insomnia.

    2 sources cited
    1. 90320. Kedia AW, Hofheins JE, Habowski SM, et al. Effects of a pre-workout supplement on lean mass, muscular performance, subjective workout experience and markers of safety. Int J Med Sci 2014;11(2):116-26.
    2. 100517. Warning Letter: Driven Sports, Inc 04/04/14. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, April 4, 2014. https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/driven-sports-inc-0404201

Everything above comes from the Natural Medicines adverse-effect record for Dendrobium — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Brentuximab Vedotin’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Brentuximab Vedotin column appears here.

Everything else you take

See Every Supplement That Interacts With Brentuximab Vedotin

This page covers Dendrobium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Brentuximab Vedotin page lists 121 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate), Adrafinil (moderate) and African Wild Potato (moderate).

By severity: 2 major · 87 moderate · 32 minor.

From our pharmacist’s overview on the Brentuximab Vedotin page

“Every entry on this page traces back to a single enzyme. Brentuximab vedotin (Adcetris), an IV treatment for Hodgkin lymphoma and certain other lymphomas, carries a chemotherapy payload the body clears through CYP3A4, and I would treat this list with real care.”

Reviewed by 2 · Jul 18, 2026

Open the Brentuximab Vedotin interaction page

One more smart check

Taking Dendrobium as Part of a Dietary Supplement Product? Check It for Interactions

We hold 117 real supplement products containing Dendrobium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dendrobium. Even though Dendrobium itself has no known interaction with Brentuximab Vedotin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dendrobium and Brentuximab Vedotin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dendrobium
Top half

#504 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Brentuximab Vedotin
Top half

#1,093 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dendrobium reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Dendrobium and Brentuximab Vedotin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dendrobium

What is Dendrobium?

  • Dry mouth and thirst
  • Supporting digestion
  • General tonic/vitality
  • Eye and skin health
  • Recovery after illness

Dendrobium is a group of orchids long used in traditional Chinese medicine, often to moisten the body and as a general tonic. Human evidence for its modern health claims is very limited, so it should be viewed as a traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding because safety isn't known.

Dendrobium nobile · Orchidaceae · Stems (and sometimes whole plant) · Dried stems, tea, decoction, powder, capsules, tinctures

An interaction check asks whether these two react with each other — it does not ask whether Dendrobium is a good idea for someone in your situation. Here is what our Dendrobium record says about it on its own.

Dendrobium: dosing

There is no well-established standard dose of Dendrobium. Traditional preparations are usually made as teas or decoctions from the dried stems, while modern products come in capsules, powders, and liquid extracts with very different strengths.Because a proven safe and effective dose has not been set, the best approach is to follow the directions on the product label and not exceed them.

From our Dendrobium monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dendrobium monograph & all interactions
Medication

About Brentuximab Vedotin Injection

What Is Brentuximab Vedotin Injection Used For?

Brand name: Adcetris

Adcetris (brentuximab vedotin) is used to treat classical Hodgkin lymphoma (cHL) in adults — including newly diagnosed advanced-stage disease, as consolidation therapy after a stem cell transplant, and in relapsed or refractory cases. It is also approved for pediatric patients aged 2 and older with previously untreated high-risk classical Hodgkin lymphoma, given in combination with chemotherapy.

Adcetris is also used for several T-cell lymphomas — including systemic anaplastic large cell lymphoma (sALCL), peripheral T-cell lymphomas (PTCL), primary cutaneous anaplastic large cell lymphoma (pcALCL), and CD30-expressing mycosis fungoides (MF). Additionally, Adcetris is used in combination with lenalidomide and a rituximab product for adults with relapsed or refractory large B-cell lymphoma (LBCL) who are not candidates for a stem cell transplant or CAR T-cell therapy.

Most-Reported Side Effects for Brentuximab Vedotin

From FAERS, the FDA’s public side-effect reporting system (10,190 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Febrile neutropenia 758 reports
Neuropathy peripheral 711 reports
Fever 682 reports
Neutropenia 586 reports
Hodgkin^s disease 459 reports
See full Brentuximab Vedotin Injection drug information
Keep checking

Other Drugs & Dendrobium

Browse every other medication we’ve checked against Dendrobium — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
461Moderate
148Minor
2,220No known interaction
Moderate

461 interactions

Showing 60 of 461 moderate interactions — see all 461 on the Dendrobium page.

Minor

148 interactions

Showing 60 of 148 minor interactions — see all 148 on the Dendrobium page.

No interaction 2,220 drugs checked — show the list
Evidence & sources

Dendrobium References

The 3 references that drive our Dendrobium monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  2. Kedia AW, Hofheins JE, Habowski SM, et al. Effects of a pre-workout supplement on lean mass, muscular performance, subjective workout experience and markers of safety. Int J Med Sci 2014;11(2):116-26.
  3. Warning Letter: Driven Sports, Inc 04/04/14. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, April 4, 2014. https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/driven-sports-inc-0404201

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dendrobium and Brentuximab Vedotin Together: Common Questions

Is it safe to take Dendrobium with Brentuximab Vedotin?
We do not list a known interaction between Dendrobium and Brentuximab Vedotin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Dendrobium and Brentuximab Vedotin combination checked?
Interactions in our licensed database are recorded against drug classes. Brentuximab Vedotin is filed under 1 classification, and Dendrobium has documented interactions with 3 drug classes — none of Brentuximab Vedotin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Dendrobium interact with any other medications?
Yes. Dendrobium has 609 documented drug interactions in our database — Brentuximab Vedotin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Brentuximab Vedotin interact with any supplements?
Yes. Brentuximab Vedotin has documented interactions with 121 supplements in our database — Dendrobium is not one of them. The Brentuximab Vedotin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Brentuximab Vedotin and Dendrobium?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.