Dhea - Fluoxymesterone Interaction
Herbal: Dhea
Also Known As: 3b-Hydroxy-Androst-5-Ene-17-One, 3BetaHydroxy-Androst-5-Ene-17-One, Androstenolone, Déhydroépiandrostérone, DHEA-S, GL701, Prasterone
Drug: Fluoxymesterone
Brand names:
Android F, Halotestin, Ora-Testryl
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Fluoxymesterone and Dhea. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Dhea Overview
Dehydroepiandrosterone (DHEA) is a natural (i.e., endogenous) hormone produced by the adrenal gland and is among the most abundant steroid hormones in the human body. It is a precursor to the hormones testosterone and estrogen, and it is thought to have various effects on the body. DHEA levels naturally decline with age. It is a popular over the counter supplement that is purported to have a variety of health benefits, including increasing muscle mass, improving cognitive function, improving mood and reducing the risk of heart disease and diabetes. The scientific evidence supporting the use of DHEA for these purposes is limited and mixed. Additionally, it could potentially interact with several different medications so if you are considering taking DHEA supplements, it is important to speak with a healthcare professional.
DHEA should not be confused with other supplements containing the letters 'DHEA'. 7-alpha-hydroxy-DHEA, 7-beta-hydroxy-DHEA, and 7-keto-DHEA, all contain DHEA as the parent compound with additional structures attached.
Fluoxymesterone Overview
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Fluoxymesterone is used to treat symptoms of low testosterone in adult men who have hypogonadism (a condition in which the body does not produce enough natural testosterone). Fluoxymesterone is used only for men with low testosterone levels caused by certain medical conditions, including disorders of the testicles, pituitary gland, (a small gland in the brain) or hypothalamus (a part of the brain) that cause hypogonadism. Fluoxymesterone is also used to stimulate puberty in men with delayed puberty. Fluoxymesterone may also be used alone or along with other medications in certain women with breast cancer that has spread to other parts of the body and can not be removed with surgery. Fluoxymesterone is in a class of medications called androgenic hormones. It works by supplying testosterone to replace the testosterone that is normally produced naturally in the body. Testosterone is a hormone produced by the body that contributes to the growth, development, and functioning of the male sexual organs and typical male characteristics. When used to treat breast cancer, testosterone works by blocking the release of estrogen to stop or slow the growth of breast cancer..
Dhea - More Interactions
Dhea interacts with 754 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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