Drug & supplement interaction

Gamboge + Clevidipine

Clevidipine brand name: Cleviprex.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Gamboge and Clevidipine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Gamboge and Clevidipine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clevidipine and Gamboge in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Gamboge safety at a glance

Gamboge overall Avoid Gamboge resin is a harsh purgative and can be toxic when swallowed.
Pregnancy Possibly Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clevidipine and Gamboge? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Clevidipine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Clevidipine is filed under a single classification — antihypertensive drugs. Gamboge has documented interactions with 5 drug classes — the most serious being corticosteroids (moderate), digoxin (lanoxin) (moderate) and diuretic drugs (moderate) — and none of Clevidipine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Gamboge Does Interact With Other Medications

Gamboge has 122 moderate known drug interactions in our database — Clevidipine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Gamboge

Covers the 2,830 medications we’ve checked against Gamboge. Pick one to open its full report.

What to actually watch for

What Gamboge Itself Has Been Linked To

This is not an interaction — nothing below involves Clevidipine. It is the side-effect record for Gamboge on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Gamboge, this list is the first place to look.

  • Stomach pain / Vomiting Additional detail

    “Orally, abdominal pain and vomiting have been reported with gamboge at doses as low as 200 mg. Deaths have been reported after ingestion of 4 grams of gamboge (18).”

    Gamboge · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    “Orally, abdominal pain and vomiting have been reported with gamboge at doses as low as 200 mg (18).”

    Gamboge · Natural Medicines adverse-effect record, reported in myasthenia gravis.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Everything above comes from the Natural Medicines adverse-effect record for Gamboge — expand a row for the licensed statement it rests on. We haven’t matched Clevidipine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Clevidipine.

Special populations

Gamboge in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Clevidipine

This page covers Gamboge only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clevidipine page lists 119 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: American Hellebore (major), American Mistletoe (major), Tyramine (major), Adrafinil (moderate) and Agmatine (moderate).

By severity: 3 major · 104 moderate · 12 minor.

From our pharmacist’s overview on the Clevidipine page

“When you are on clevidipine (Cleviprex), a hospital IV drip used to bring dangerously high blood pressure down fast, every one of the 119 supplements and herbs listed here pushes on the very thing the drug controls, and that earns this list real caution. Most of the 104 moderate entries, everyday products like fish oil among them, add…”

Reviewed by 2 · Jul 18, 2026

Open the Clevidipine interaction page

How much people look this up

Where Gamboge and Clevidipine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Gamboge
Steady interest

#901 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clevidipine
Steady interest

#2,778 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Gamboge reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Gamboge and Clevidipine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Gamboge

What is Gamboge?

  • Laxative (purgative)
  • Expelling intestinal worms
  • Traditional wound care
  • Use as a yellow dye/pigment

Gamboge is a bright yellow tree resin used historically as a strong laxative and as an artists' pigment, but it is toxic in even modest amounts and is not a safe dietary supplement. Modern interest centers on its compound gambogic acid in laboratory cancer research, which does not make the raw resin safe to take. We recommend avoiding oral use of gamboge.

Garcinia hanburyi · Clusiaceae · Dried resin (gum-resin) from the bark/latex · Resin powder, traditional pills, paint pigment (not a typical modern supplement)

An interaction check asks whether these two react with each other — it does not ask whether Gamboge is a good idea for someone in your situation. Here is what our Gamboge record says about it on its own.

Gamboge: dosing

There is no established safe dose of gamboge for any health use, and we do not provide one. Because the resin is considered toxic and is not a recognized supplement, there are no reliable, standardized products with proven dosing.If you ever encounter a product that contains gamboge, do not take it without first talking to a pharmacist or doctor. In general, our recommendation is to avoid oral use entirely and choose safer, well-studied options for problems like constipation.

From our Gamboge monograph — the full record covers uses, side effects and every documented interaction.

Read the full Gamboge monograph & all interactions
Medication

About Clevidipine

Most-Reported Side Effects for Clevidipine

From FAERS, the FDA’s public side-effect reporting system (362 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hypotension 30 reports
Hypoxia 26 reports
Ventilation perfusion mismatch 25 reports
Oxygen saturation decreased 18 reports
Tachycardia 17 reports
Keep checking

Other Drugs & Gamboge

Browse every other medication we’ve checked against Gamboge — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
122Moderate
0Minor
2,707No known interaction
Moderate

122 interactions

Showing 60 of 122 moderate interactions — see all 122 on the Gamboge page.

No interaction 2,707 drugs checked — show the list
Evidence & sources

Gamboge References

The 2 references that drive our Gamboge monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Gamboge and Clevidipine Together: Common Questions

Is it safe to take Gamboge with Clevidipine?
We do not list a known interaction between Gamboge and Clevidipine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Gamboge and Clevidipine combination checked?
Interactions in our licensed database are recorded against drug classes. Clevidipine is filed under 1 classification, and Gamboge has documented interactions with 5 drug classes — none of Clevidipine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Gamboge interact with any other medications?
Yes. Gamboge has 122 documented drug interactions in our database — Clevidipine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Clevidipine interact with any supplements?
Yes. Clevidipine has documented interactions with 119 supplements in our database — Gamboge is not one of them. The Clevidipine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Clevidipine and Gamboge?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.