Drug & supplement interaction

Henbane + Uridine Triacetate

Uridine Triacetate brand names: Xuriden, Vistogard.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Henbane and Uridine Triacetate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Uridine Triacetate states a food rule worth keeping to.

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Interaction report

Henbane and Uridine Triacetate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Uridine Triacetate and Henbane in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Henbane safety at a glance

Henbane overall Avoid Henbane is a toxic plant that can cause severe poisoning and death, even in small amounts.
Pregnancy Likely Unsafe When used orally because of its risk of poisoning. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally because of its risk of poisoning. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Uridine Triacetate and Henbane? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Uridine Triacetate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Uridine Triacetate is filed under a single classification — oral drugs. Henbane has documented interactions with 1 drug class — the most serious being anticholinergic drugs (major) — and none of Uridine Triacetate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Henbane Does Interact With Other Medications

Henbane has 195 major, known drug interactions in our database — Uridine Triacetate isn’t one of them. If you take anything else, check it against the full list below.

Major 195 No known interaction 2,635 (incl. Uridine Triacetate)
Taking anything else?

Check Another of Your Medications Against Henbane

Covers the 2,830 medications we’ve checked against Henbane. Pick one to open its full report.

What to actually watch for

What Henbane Itself Has Been Linked To

This is not an interaction — nothing below involves Uridine Triacetate. It is the side-effect record for Henbane on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Henbane, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Memory problems / Hallucinations / Confusion Worth acting on Additional detail

    “Orally, henbane can cause anticholinergic effects including dry mouth, vision disturbances, tachycardia, difficult urination, constipation, and skin flushing (2,18). At higher doses, poisoning can occur due to the hyoscyamine and scopolamine constituents of henbane.”

    Henbane · Natural Medicines adverse-effect record, reported in constipation.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 100917. Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med 2007;14(6):348-50.

    “Orally, high doses of henbane can cause toxicity due to its hyoscyamine and scopolamine constituents. Neurologic symptoms of henbane toxicity include somnolence, followed by CNS excitation involving restlessness, hallucinations, memory impairment, delirium, and manic episodes, followed by exhaustion and coma (2,18,100917).”

    Henbane · Natural Medicines adverse-effect record, reported in memory.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 100917. Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med 2007;14(6):348-50.
  • Unsteadiness Worth acting on Additional detail

    Recorded for Henbane in the same Natural Medicines adverse-effect record shown under Memory problems / Hallucinations / Confusion above.

  • Flushing Additional detail

    “Orally, henbane reduces sweating, resulting in flushing of the skin and hyperpyrexia (2,18,100917).”

    Henbane · Natural Medicines adverse-effect record, reported in niacin-induced flushing.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 100917. Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med 2007;14(6):348-50.
  • Sweating Additional detail

    Recorded for Henbane in the same Natural Medicines adverse-effect record shown under Flushing above.

  • Dry mouth Additional detail

    Recorded for Henbane in the same Natural Medicines adverse-effect record shown under Memory problems / Hallucinations / Confusion above.

  • A fast or pounding heartbeat Additional detail

    “Orally, henbane can cause tachycardia, especially at higher doses (2,18,100917).”

    Henbane · Natural Medicines adverse-effect record, reported in irregular heartbeat.

    3 sources cited
    1. 2. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
    2. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    3. 100917. Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med 2007;14(6):348-50.
  • Drowsiness / Anxiety or restlessness Additional detail

    Recorded for Henbane in the same Natural Medicines adverse-effect record shown under Memory problems / Hallucinations / Confusion above.

Showing the 10 most notable of 11 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Henbane — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Uridine Triacetate’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Uridine Triacetate column appears here.

Special populations

Henbane in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally because of its risk of poisoning.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Uridine Triacetate Products Have a Food Rule — Henbane Should Not Break It

At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Henbane on an empty stomach out of habit, keep them separate — and take Uridine Triacetate with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Uridine Triacetate products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Administer the dose with food (applesauce, pudding or yogurt) or in milk or infant formula.

From the Dosage and Administration section of the FDA label we read for Uridine Triacetate — where that label names a specific product, the instruction is that product's. See the Uridine Triacetate drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Uridine Triacetate

This page covers Henbane only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Uridine Triacetate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Uridine Triacetate page

“Uridine triacetate is a drug you take when absorption truly cannot fail, whether as Vistogard, the emergency antidote for fluorouracil or capecitabine overdose, or as Xuriden for hereditary orotic aciduria. That is why the 17 supplement interactions on file deserve real care rather than a shrug.”

Reviewed by 2 · Jul 18, 2026

Open the Uridine Triacetate interaction page

One more smart check

Taking Henbane as Part of a Dietary Supplement Product? Check It for Interactions

We hold 6 real supplement products containing Henbane, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Henbane. Even though Henbane itself has no known interaction with Uridine Triacetate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Henbane and Uridine Triacetate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Henbane
Steady interest

#940 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Uridine Triacetate
Steady interest

#2,668 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Henbane reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Henbane and Uridine Triacetate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Henbane

What is Henbane?

Henbane
  • Pain relief
  • Muscle spasms and cramps
  • Sleep and sedation
  • Asthma and breathing problems (traditional)
  • Toothache (traditional)

Henbane is a highly poisonous plant containing potent alkaloids like hyoscyamine and scopolamine, and even small amounts can cause serious or deadly poisoning. While its compounds have real medical uses, these belong in carefully controlled prescription drugs, not in self-made or self-dosed herbal products. We strongly advise against using henbane as a supplement.

Hyoscyamus niger · Solanaceae · Leaves, flowering tops, and seeds · Rarely available; historically used as dried herb, tinctures, extracts, and topical oils. Not recommended for self-use.

An interaction check asks whether these two react with each other — it does not ask whether Henbane is a good idea for someone in your situation. Here is what our Henbane record says about it on its own.

Henbane: dosing

There is no safe, established dose of henbane for self-use. The amount of toxic alkaloids varies widely from plant to plant and product to product, which makes safe dosing impossible at home.The medical compounds found in henbane (such as hyoscyamine and scopolamine) are only used safely as standardized prescription medicines, prepared and dosed by professionals.We do not recommend using henbane as a supplement.

From our Henbane monograph — the full record covers uses, side effects and every documented interaction.

Read the full Henbane monograph & all interactions
Medication

About Uridine Triacetate

What Is Uridine Triacetate Used For?

Brand names: Xuriden, Vistogard

Uridine triacetate is available as two different products for two distinct uses. Vistogard is used for emergency treatment after an overdose of the chemotherapy drugs fluorouracil or capecitabine — or when someone develops severe, early, or life-threatening side effects from those drugs (such as heart or nervous system problems, severe digestive reactions, or a dangerous drop in white blood cells) within 96 hours of their last dose.

Xuriden is used to treat hereditary orotic aciduria, a rare inherited condition in which the body cannot make enough of a building block called uridine, causing a buildup of orotic acid and problems with blood cell production and other body functions. Both products are approved for adults and children.

See full Uridine Triacetate drug information
Keep checking

Other Drugs & Henbane

Browse every other medication we’ve checked against Henbane — both the ones with a known interaction and the ones without. Select any drug for the full detail.

195Major
0Moderate
0Minor
2,634No known interaction
195 Major 2,634 No interaction
Major

195 interactions

Showing 60 of 195 major interactions — see all 195 on the Henbane page.

No interaction 2,634 drugs checked — show the list

We also checked Henbane against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,634 medications checked with no known interaction — see the full Henbane list.

See the full Henbane interactions page
See every supplement checked against Uridine Triacetate, ranked by severity
Evidence & sources

Henbane References

The 3 references that drive our Henbane monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Doneray H, Orbak Z, Karakelleoglu C. Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy. Eur J Emerg Med 2007;14(6):348-50.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Henbane and Uridine Triacetate Together: Common Questions

Is it safe to take Henbane with Uridine Triacetate?
We do not list a known interaction between Henbane and Uridine Triacetate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Henbane and Uridine Triacetate at the same time of day?
At least one FDA label for a product containing Uridine Triacetate says to take it with food. If you take Henbane on an empty stomach out of habit, keep them separate and take Uridine Triacetate with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Uridine Triacetate products can differ — so check the directions on your own box. This is about absorption, not an interaction.
How was the Henbane and Uridine Triacetate combination checked?
Interactions in our licensed database are recorded against drug classes. Uridine Triacetate is filed under 1 classification, and Henbane has documented interactions with 1 drug class — none of Uridine Triacetate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Henbane interact with any other medications?
Yes. Henbane has 195 documented drug interactions in our database — Uridine Triacetate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Uridine Triacetate interact with any supplements?
Yes. Uridine Triacetate has documented interactions with 17 supplements in our database — Henbane is not one of them. The Uridine Triacetate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Henbane monograph Uses, safety profile, and every drug interaction in one place Uridine Triacetate drug information The full plain-English guide to this medication Uridine Triacetate supplement interactions Every supplement checked against Uridine Triacetate, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Uridine Triacetate and Henbane?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.