Drug & supplement interaction

Laburnum + Diazepam

Diazepam brand names: Valium, Valium injection, Diastat AcuDial, Valtoco.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Laburnum and Diazepam in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Laburnum and Diazepam

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Diazepam and Laburnum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Laburnum at all — not against Diazepam, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Laburnum safety at a glance

Laburnum overall Avoid All parts of the plant are poisonous and ingestion can cause severe toxicity.
Pregnancy Unsafe When used orally. All parts of the plant contain toxic alkaloids that are reported to cross the placenta and enter breast milk. Read the full pregnancy detail
Breastfeeding Unsafe When used orally. All parts of the plant contain toxic alkaloids that are reported to cross the placenta and enter breast milk. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Diazepam and Laburnum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Laburnum and Diazepam May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Seizures Worth acting on Additional detail

    Laburnum

    “Symptoms of laburnum poisoning include headache, dizziness, weakness, drowsiness, incoordination, ataxia, tremors, confusion, delirium, coma, and seizures.”

    Laburnum · Natural Medicines adverse-effect record, reported in cluster headache.

    2 sources cited
    1. 101220. Bramley A, Goulding R. Laburnum "poisoning". Br Med J (Clin Res Ed). 1981;283(6301):1220-1.
    2. 101221. Schep LJ, Slaughter RJ, Beasley DMG. Nicotinic plant poisoning. Clin Toxicol (Phila). 2009;47(8):771-81. doi: 10.1080/15563650903252186. PubMed

    Diazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Diazepam. Read the label on DailyMed ›

  • Drowsiness Additional detail

    Laburnum

    Recorded for Laburnum in the same Natural Medicines adverse-effect record shown under Seizures above.

    Diazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Diazepam. Read the label on DailyMed ›

  • Diarrhea Additional detail

    Laburnum

    “Orally, the fatal adult dose of laburnum is estimated to be about 15-20 seeds or 3-4 unripe berries (18). Many cases of poisoning involve children who ingest small quantities of seeds and experience primarily gastrointestinal symptoms, with a relatively rapid recovery.”

    Laburnum · Natural Medicines adverse-effect record, reported in diarrhea.

    4 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 101220. Bramley A, Goulding R. Laburnum "poisoning". Br Med J (Clin Res Ed). 1981;283(6301):1220-1.
    3. 101221. Schep LJ, Slaughter RJ, Beasley DMG. Nicotinic plant poisoning. Clin Toxicol (Phila). 2009;47(8):771-81. doi: 10.1080/15563650903252186. PubMed
    4. 101222. Musshoff F, Madea B. Fatal cytisine intoxication and analysis of biological samples with LC-MS/MS. Forensic Sci Int. 2009;186(1-3):e1-4. doi: 10.1016/j.forsciint.2009.01.011. PubMed

    “The most common symptoms of laburnum poisoning include mouth, throat, and stomach pain, and nausea and vomiting. In more severe cases there is excessive salivation, and diarrhea.”

    Laburnum · Natural Medicines adverse-effect record, reported in diarrhea.

    3 sources cited
    1. 101220. Bramley A, Goulding R. Laburnum "poisoning". Br Med J (Clin Res Ed). 1981;283(6301):1220-1.
    2. 101221. Schep LJ, Slaughter RJ, Beasley DMG. Nicotinic plant poisoning. Clin Toxicol (Phila). 2009;47(8):771-81. doi: 10.1080/15563650903252186. PubMed
    3. 101222. Musshoff F, Madea B. Fatal cytisine intoxication and analysis of biological samples with LC-MS/MS. Forensic Sci Int. 2009;186(1-3):e1-4. doi: 10.1016/j.forsciint.2009.01.011. PubMed

    Diazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Diazepam. Read the label on DailyMed ›

  • Headache Additional detail

    Laburnum

    Recorded for Laburnum in the same Natural Medicines adverse-effect record shown under Diarrhea above.

    Diazepam

    Listed in the ADVERSE REACTIONS section of the FDA label for Diazepam. Read the label on DailyMed ›

Reported for Laburnum but not commonly for Diazepam: an irregular heartbeat, sweating, stomach pain and raised blood pressure.

Effects for Diazepam come from the ADVERSE REACTIONS section of its FDA label; effects for Laburnum come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Laburnum in Pregnancy & Breastfeeding

Pregnancy And Lactation Unsafe

When used orally. All parts of the plant contain toxic alkaloids that are reported to cross the placenta and enter breast milk.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Laburnum or Diazepam

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Laburnum or Diazepam, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Diazepam

This page covers Laburnum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Diazepam page lists 244 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 9 major · 191 moderate · 44 minor.

Open the Diazepam interaction page

One more smart check

Taking Laburnum as Part of a Dietary Supplement Product? Check It for Interactions

We hold 11 real supplement products containing Laburnum, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Laburnum. Even though Laburnum itself has no known interaction with Diazepam, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Laburnum and Diazepam Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Laburnum
Steady interest

#1,090 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Diazepam
Top 10%

#244 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Laburnum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Laburnum and Diazepam records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Laburnum

What is Laburnum?

  • Historically explored as a smoking-cessation aid (due to cytisine content)
  • Traditional folk use as a purgative or emetic
  • Ornamental garden plant
  • Source of the alkaloid cytisine

Laburnum is a poisonous ornamental tree, not a safe dietary supplement. All parts of the plant—especially the seeds—contain the toxic alkaloid cytisine and can cause serious poisoning. Do not eat or take any part of the Laburnum plant; consult a doctor or poison control immediately if ingestion is suspected.

Laburnum anagyroides · Fabaceae · Seeds, flowers, bark, and other plant parts (all considered toxic) · Not used as a commercial supplement; the plant is grown as an ornamental tree

An interaction check asks whether these two react with each other — it does not ask whether Laburnum is a good idea for someone in your situation. Here is what our Laburnum record says about it on its own.

Laburnum: dosing

There is no safe or established dose of Laburnum. It is not a dietary supplement, and no amount of the raw plant is considered safe to consume.Any information you may see about cytisine doses refers to purified, prescription-type products used under medical supervision in certain countries—not to the Laburnum plant. Do not attempt to make or take anything from this tree.

From our Laburnum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Laburnum monograph & all interactions
Medication

About Diazepam

What Is Diazepam Used For?

Brand names: Valium, Valium injection, Diastat AcuDial, Valtoco

Diazepam treats several different problems, depending on the product. Oral diazepam (tablets such as Valium, and oral solution) is used for anxiety disorders, short-term relief of anxiety symptoms, and symptom relief in acute alcohol withdrawal. It is also used alongside other treatments for muscle spasm and, adjunctively, for convulsive disorders (seizure disorders).

Diazepam injection is used for the same anxiety and alcohol withdrawal uses. It is also used before endoscopic procedures, before surgery, and before cardioversion (when given intravenously). It helps with muscle spasm and tetanus, and with status epilepticus (a prolonged, dangerous seizure) as an add-on. Diazepam rectal gel and Valtoco nasal spray are used only for seizure clusters (acute repetitive seizures) in people with epilepsy ages 2 and older.

See full Diazepam drug information
Keep checking

Other Drugs & Laburnum

Browse every other medication we’ve checked against Laburnum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Laburnum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Laburnum list.

See the full Laburnum interactions page
See every supplement checked against Diazepam, ranked by severity
Evidence & sources

Laburnum References

The 4 references that drive our Laburnum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Bramley A, Goulding R. Laburnum "poisoning". Br Med J (Clin Res Ed). 1981;283(6301):1220-1.
  3. Schep LJ, Slaughter RJ, Beasley DMG. Nicotinic plant poisoning. Clin Toxicol (Phila). 2009;47(8):771-81. doi: 10.1080/15563650903252186. PubMed
  4. Musshoff F, Madea B. Fatal cytisine intoxication and analysis of biological samples with LC-MS/MS. Forensic Sci Int. 2009;186(1-3):e1-4. doi: 10.1016/j.forsciint.2009.01.011. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Laburnum and Diazepam Together: Common Questions

Is it safe to take Laburnum with Diazepam?
We do not list a known interaction between Laburnum and Diazepam. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Laburnum and Diazepam have any of the same side effects?
Yes — our sources link each of them separately to 4 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Diazepam interact with any supplements?
Yes. Diazepam has documented interactions with 244 supplements in our database — Laburnum is not one of them. The Diazepam interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Laburnum monograph Uses, safety profile, and every drug interaction in one place Diazepam drug information The full plain-English guide to this medication Diazepam supplement interactions Every supplement checked against Diazepam, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Diazepam and Laburnum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.