Drug & supplement interaction

Limosilactobacillus Fermentum + Colestipol

Colestipol brand name: Colestid.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Limosilactobacillus Fermentum and Colestipol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Colestipol states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

Know someone taking this? Share
Facebook Post Reddit Email
On this page
Interaction report

Limosilactobacillus Fermentum and Colestipol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Colestipol and Limosilactobacillus Fermentum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Limosilactobacillus Fermentum safety at a glance

Limosilactobacillu... overall Use caution Generally well tolerated in healthy people, but evidence and quality vary by product and strain.
Pregnancy Use caution Some strains have been studied in pregnancy, but safety is not firmly established, so check with your doctor first.
Breastfeeding Possibly Safe When used orally and appropriately. Limosilactobacillus fermentum CECT5716 has been used with apparent safety when breastfeeding for up to 16 weeks. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Colestipol and Limosilactobacillus Fermentum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Colestipol

Interactions in our licensed database are recorded against drug classes, not just single drug names. Colestipol is filed under 2 classifications — bile acid sequestrants, oral drugs. Limosilactobacillus Fermentum has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Colestipol’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Limosilactobacillus Fermentum Does Interact With Other Medications

Limosilactobacillus Fermentum has 182 moderate known drug interactions in our database — Colestipol isn’t one of them. If you take anything else, check it against the full list below.

Moderate 182 No known interaction 2,648 (incl. Colestipol)
Taking anything else?

Check Another of Your Medications Against Limosilactobacillus Fermentum

Covers the 2,830 medications we’ve checked against Limosilactobacillus Fermentum. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Limosilactobacillus Fermentum and Colestipol May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Stomach upset Additional detail

    Limosilactobacillus Fermentum

    “Since Limosilactobacillus fermentum preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Limosilactobacillus Fermentum · Natural Medicines adverse-effect record, reported in sepsis.

    6 sources cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
    2. 110917. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
    3. 110918. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
    4. 110920. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
    5. 110921. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
    6. 112565. Achuthanandan S, Dhaliwal A, Lu T, Sharma K. Brain abscess due to Lactobacillus fermentum in an uncontrolled diabetic. Cureus 2022;14(6):e26360. PubMed

    Colestipol

    Listed in the ADVERSE REACTIONS section of the FDA label for Colestipol. Read the label on DailyMed ›

Reported for Limosilactobacillus Fermentum but not commonly for Colestipol: a higher chance of infection.

Effects for Colestipol come from the ADVERSE REACTIONS section of its FDA label; effects for Limosilactobacillus Fermentum come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Limosilactobacillus Fermentum in Pregnancy & Breastfeeding

Lactation Possibly Safe

When used orally and appropriately. Limosilactobacillus fermentum CECT5716 has been used with apparent safety when breastfeeding for up to 16 weeks.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Colestipol Products Have a Food Rule — Limosilactobacillus Fermentum Should Not Break It

At least one FDA label for a product containing Colestipol says to take it on an empty stomach. Most supplements — Limosilactobacillus Fermentum included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Colestipol on its own and move Limosilactobacillus Fermentum to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Colestipol products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Patients should take other drugs at least one hour before or four hours after colestipol hydrochloride tablets to minimize possible interference with their absorption.

From the Dosage and Administration section of the FDA label we read for Colestipol — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

From our Q&A

Questions About Limosilactobacillus Fermentum or Colestipol

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Limosilactobacillus Fermentum or Colestipol, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Colestipol

This page covers Limosilactobacillus Fermentum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Colestipol page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Colestipol page

“Take colestipol (Colestid), a cholesterol drug that works by trapping bile acids in your gut, and nearly every one of the 18 supplement interactions on file comes down to absorption. Only one rates major, activated charcoal, and it belongs at the top of your reading.”

Reviewed by 2 · Jul 18, 2026

Open the Colestipol interaction page

How much people look this up

Where Limosilactobacillus Fermentum and Colestipol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Limosilactobacillus Fermentum
Top half

#549 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Colestipol
Top 25%

#487 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Limosilactobacillus Fermentum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Limosilactobacillus Fermentum and Colestipol records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Limosilactobacillus Fermentum

What is Limosilactobacillus Fermentum?

  • Digestive health
  • Immune support
  • Vaginal and urinary health
  • Cholesterol support
  • Oral health

Limosilactobacillus fermentum (formerly Lactobacillus fermentum) is a probiotic bacterium found in fermented foods and the human body, used to support gut, immune, and women's health. Early research is promising for some uses but most evidence is preliminary, and effects can differ by strain. It is generally well tolerated in healthy people, but talk to your pharmacist or doctor before starting, especially if your immune system is weak.

Limosilactobacillus fermentum · Lactobacillaceae · Whole live bacteria (probiotic strain) · Capsules, tablets, powders, fermented foods, and combination probiotic products

An interaction check asks whether these two react with each other — it does not ask whether Limosilactobacillus Fermentum is a good idea for someone in your situation. Here is what our Limosilactobacillus Fermentum record says about it on its own.

Limosilactobacillus Fermentum: dosing

There is no official standardized dose for Limosilactobacillus fermentum. Probiotic amounts are usually measured in colony-forming units (CFU), and the right amount depends on the strain and the product.The best approach is to follow the directions on the product label. Do not assume more is better.

From our Limosilactobacillus Fermentum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Limosilactobacillus Fermentum monograph & all interactions
Medication

About Colestipol

What Is Colestipol Used For?

Brand name: Colestid

Colestipol — available as oral suspension and tablets under brands including Colestid, Flavored Colestid, and Colestipol Hydrochloride — is used as part of a broader treatment plan (including diet) to lower elevated LDL cholesterol in adults with primary hypercholesterolemia (a condition where LDL cholesterol stays high despite dietary changes).

It is not a standalone fix. Diet, weight management, and other lifestyle changes come first, and colestipol is added when those steps alone aren't enough to reach target LDL levels.

See full Colestipol drug information
Keep checking

Other Drugs & Limosilactobacillus Fermentum

Browse every other medication we’ve checked against Limosilactobacillus Fermentum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
182 Moderate 2,647 No interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Limosilactobacillus Fermentum page.

No interaction 2,647 drugs checked — show the list

We also checked Limosilactobacillus Fermentum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,647 medications checked with no known interaction — see the full Limosilactobacillus Fermentum list.

See the full Limosilactobacillus Fermentum interactions page
See every supplement checked against Colestipol, ranked by severity
Evidence & sources

Limosilactobacillus Fermentum References

The 12 references that drive our Limosilactobacillus Fermentum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  3. Ranchal P, Gupta R, Goldberg R, A Lobo S, Pascual A, El Khoury MY. Penicillin-sensitive Lactobacillus jensenii bacteremia. Am J Ther 2021;28(2):e250-e252. PubMed
  4. Grazioli-Gauthier L, Rigamonti E, Leo LA, Martinetti Lucchini G, Lo Priore E, Bernasconi E. Lactobacillus jensenii mitral valve endocarditis: Case report, literature review and new perspectives. IDCases 2022;27:e01401. PubMed
  5. Toprak NU, Bozan T, Yilmaz S, Buyukbayrak EE, Tigen ET. Polymicrobial bacteremia due to Lactobacillus jensenii and Veillonella montpellierensis in a pregnant patient; case report and review of literature. Anaerobe 2022;75:102576. PubMed
  6. Chazan B, Raz R, Shental Y, Sprecher H, Colodner R. Bacteremia and pyelonephritis caused by Lactobacillus jensenii in a patient with urolithiasis. Isr Med Assoc J 2008;10(2):164-5.
  7. Achuthanandan S, Dhaliwal A, Lu T, Sharma K. Brain abscess due to Lactobacillus fermentum in an uncontrolled diabetic. Cureus 2022;14(6):e26360. PubMed
  8. Pastor-Villaescusa B, Hurtado JA, Gil-Campos M, et al. Effects of Lactobacillus fermentum CECT5716 Lc40 on infant growth and health: a randomised clinical trial in nursing women. Benef Microbes 2020;11(3):235-244. PubMed
  9. Jiménez-Gutiérrez JM, Peláez-Luna M, Campos-Murguía A. A rare case of emphysematous gastritis caused by Lactobacillus fermentum in a patient with diabetes. Rev Esp Enferm Dig 2021;113(9):670-671. PubMed
  10. Greig JR, Eltringham IJ, Birthistle K. Primary peritonitis due to Lactobacillus fermentum. J Infect 1998;36(2):242-3. PubMed
  11. Woo PC, Lau SK, Lin AW, Curreem SO, Fung AM, Yuen KY. Surgical site abscess caused by Lactobacillus fermentum identified by 16S ribosomal RNA gene sequencing. Diagn Microbiol Infect Dis 2007;58(2):251-4. PubMed
  12. Gallemore GH, Mohon RT, Ferguson DA. Lactobacillus fermentum endocarditis involving a native mitral valve. J Tenn Med Assoc 1995;88(8):306-8.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Limosilactobacillus Fermentum and Colestipol Together: Common Questions

Is it safe to take Limosilactobacillus Fermentum with Colestipol?
We do not list a known interaction between Limosilactobacillus Fermentum and Colestipol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Limosilactobacillus Fermentum and Colestipol have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Should I take Limosilactobacillus Fermentum and Colestipol at the same time of day?
At least one FDA label for a product containing Colestipol says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Colestipol on its own and move Limosilactobacillus Fermentum to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Limosilactobacillus Fermentum and Colestipol combination checked?
Interactions in our licensed database are recorded against drug classes. Colestipol is filed under 2 classifications, and Limosilactobacillus Fermentum has documented interactions with 1 drug class — none of Colestipol's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Limosilactobacillus Fermentum interact with any other medications?
Yes. Limosilactobacillus Fermentum has 182 documented drug interactions in our database — Colestipol is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Colestipol interact with any supplements?
Yes. Colestipol has documented interactions with 18 supplements in our database — Limosilactobacillus Fermentum is not one of them. The Colestipol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Limosilactobacillus Fermentum monograph Uses, safety profile, and every drug interaction in one place Colestipol drug information The full plain-English guide to this medication Colestipol supplement interactions Every supplement checked against Colestipol, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 12 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Colestipol and Limosilactobacillus Fermentum?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.