Drug & supplement interaction

Soy + Dalbavancin Hydrochloride

Dalbavancin Hydrochloride brand name: Dalvance.

Minor Interaction
The bottom line Minor

Soy has a minor interaction with Dalbavancin Hydrochloride. Theoretically, antibiotics may decrease the activity of soy isoflavones.

Read the full interaction report
SeverityMinor
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Soy and Dalbavancin Hydrochloride

Here is the interaction we found between these two, with the evidence behind it.

Minor

ANTIBIOTIC DRUGS

Why this applies to Dalbavancin Hydrochloride

Dalbavancin Hydrochloride falls under ANTIBIOTIC DRUGS — the group Soy interacts with.

Theoretically, antibiotics may decrease the activity of soy isoflavones.
Intestinal bacteria are responsible in part for converting soy isoflavones into their active forms. Antibiotics may decrease the amount of intestinal bacteria and decrease its ability to convert isoflavones.
Severity Minor Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the interesting part about this pairing: it actually runs the other direction from what most people worry about. Dalbavancin won't be affected by soy at all. Your antibiotic will still do its job fighting the skin infection just the same. The concern is what dalbavancin might do to the soy.

Your gut bacteria help turn soy isoflavones into their more active forms. Since dalbavancin is an antibiotic, it can knock down some of those helpful bacteria, so your body may get a little less benefit from soy while you're being treated. This is only a theory based on lab data, and dalbavancin is given as a short infusion, so any effect is likely small and temporary. If you take soy for a specific reason, just mention it to your pharmacist.

References
  1. Morito K, Hirose T, Kinjo J, et al. Interaction of phytoestrogens with estrogen receptors alpha and beta. Biol Pharm Bull 2001;24:351-6. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Soy Also Interacts With Other Medications

Soy has 9 major, 343 moderate, 258 minor known drug interactions in our database — the Dalbavancin Hydrochloride one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Soy

Covers the 2,830 medications we’ve checked against Soy. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Dalbavancin Hydrochloride

This page covers Soy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Dalbavancin Hydrochloride page lists 27 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Bacillus Coagulans (moderate), Bacillus Subtilis (moderate), Bifidobacterium Animalis Subsp. Lactis (moderate), Bifidobacterium Bifidum (moderate) and Bifidobacterium Breve (moderate).

By severity: 26 moderate · 1 minor.

From our pharmacist’s overview on the Dalbavancin Hydrochloride page

“Everything on the dalbavancin (Dalvance) interaction list points in one direction. No supplement on file makes this IV skin-infection antibiotic dangerous or weaker; instead, dalbavancin can kill the live organisms in probiotic products, so the supplement is the one that loses.”

Reviewed by 2 · Jul 18, 2026

Open the Dalbavancin Hydrochloride interaction page

One more smart check

Taking Soy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 821 real supplement products containing Soy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Soy. Your product may carry other ingredients that interact with Dalbavancin Hydrochloride too, on top of Soy — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Soy and Dalbavancin Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Soy
Top 25%

#229 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Dalbavancin Hydrochloride
Steady interest

#2,455 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Soy

What is Soy?

  • Menopause symptoms (hot flashes)
  • Heart and cholesterol health
  • Bone health
  • Plant-based protein source
  • General nutrition

Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones. Eating soy foods as part of a balanced diet is generally considered safe for most people, and there is moderate evidence it may modestly help cholesterol and some menopause symptoms, though results vary. Talk with your pharmacist or doctor before using concentrated soy isoflavone supplements, especially if you have a history of hormone-sensitive conditions.

Read the full Soy monograph & all interactions
Medication

About Dalbavancin Injection

What Is Dalbavancin Injection Used For?

Brand name: Dalvance

Dalvance (dalbavancin) injection is approved to treat acute bacterial skin and skin structure infections (ABSSSI) in adults and children from birth through age 17. These are serious bacterial skin infections that require treatment with an antibacterial given by IV.

It works against specific Gram-positive bacteria, including Staphylococcus aureus (both methicillin-susceptible and methicillin-resistant strains, known as MRSA), several Streptococcus species, and vancomycin-susceptible Enterococcus faecalis. It should only be used when one of these susceptible bacteria is proven or strongly suspected to be causing the infection.

See full Dalbavancin Injection drug information
Keep checking

Other Drugs & Soy

Browse every other medication we’ve checked against Soy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

9Major
343Moderate
258Minor
2,219No known interaction
Major

9 interactions

Moderate

343 interactions

Showing 60 of 343 moderate interactions — see all 343 on the Soy page.

Minor

258 interactions

Showing 60 of 258 minor interactions — see all 258 on the Soy page.

No interaction 2,219 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Soy and Dalbavancin Hydrochloride Together: Common Questions

Can you take Soy with Dalbavancin Hydrochloride?
There is only a minor interaction, which is usually not serious. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Soy and Dalbavancin Hydrochloride interaction?
We rate it Minor. This interaction is generally not clinically significant, but it remains worth noting and discussing with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Dalbavancin Hydrochloride and Soy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.