Herb & supplement monograph

Pectin Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Pectin interacts with medications. The heart of this page is the interaction list — every drug Pectin is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Pectin is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Pectin Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Pectin drug interaction appears low for most people, since the main concern is reduced absorption of certain medicines rather than any dangerous effect. None of the listed interactions are rated major, and the evidence behind each one is limited or based on combination products rather than pectin alone.

Interactions deserving the most attention

The interaction that deserves the most attention involves digoxin, a heart medicine with a narrow margin between helpful and harmful levels; a small study found much lower digoxin absorption when it was taken with a kaolin-pectin product, though it is not clear whether pectin itself was responsible. Case reports also suggest pectin may blunt the cholesterol-lowering effect of lovastatin, and a small study found reduced absorption of tetracycline antibiotics with a combination product containing pectin. In each case, the shared theme is pectin possibly binding the medicine in the gut and lowering the amount the body takes in.

What the rest of the list means

A couple dozen medications appear on the list, but that does not mean every combination causes real harm. As a soluble fiber, pectin's predicted effect is mostly theoretical, based on the idea that fiber can reduce how well some medicines are absorbed. Several of the key studies used pectin mixed with other ingredients, so pectin's role on its own remains uncertain.

Check your medications against Pectin

Based on HelloPharmacist’s Pectin interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Pectin

23 medications have a known interaction with Pectin, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
Amphotericin, TetracyclineMysteclin-F
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Amphotericin, Tetracycline interaction
Bismuth Subsalicylate, Metronidazole, TetracyclineHelidac
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Bismuth Subsalicylate, Metronidazole, Tetracycline interaction Bismuth Subsalicylate, Metronidazole, Tetracycline drug page: uses, dosage & side effects
ChlortetracyclineAureomycin
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Chlortetracycline interaction
DemeclocyclineDeclomycin
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Demeclocycline interaction Demeclocycline drug page: uses, dosage & side effects
DigoxinDigitek, Lanoxicaps, Lanoxin
Moderate Digoxin (lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.

Read the full Pectin + Digoxin interaction Digoxin drug page: uses, dosage & side effects
DoripenemDoribax
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Doripenem interaction Doripenem drug page: uses, dosage & side effects
DoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Doxycycline interaction Doxycycline drug page: uses, dosage & side effects
Doxycycline HyclateActiclate, Acticlate Cap, Lymepak
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Doxycycline Hyclate interaction Doxycycline Hyclate drug page: uses, dosage & side effects
Doxycycline MonohydrateErfacea
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Doxycycline Monohydrate interaction
DoxycylineDoxychel
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Doxycyline interaction Doxycyline drug page: uses, dosage & side effects
EravacyclineXerava
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Eravacycline interaction Eravacycline drug page: uses, dosage & side effects
LovastatinAltocor, Mevacor
Moderate Lovastatin (mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.

Read the full Pectin + Lovastatin interaction Lovastatin drug page: uses, dosage & side effects
Metronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interaction Metronidazole, Tetracyline, Bismuth Subcitrate Potassium drug page: uses, dosage & side effects
MinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Minocycline interaction Minocycline drug page: uses, dosage & side effects
Minocycline HydrochlorideMinolira, Ximino
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Minocycline Hydrochloride interaction Minocycline Hydrochloride drug page: uses, dosage & side effects
Niacin, LovastatinAdvicor
Moderate Lovastatin (mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.

Read the full Pectin + Niacin, Lovastatin interaction
Omadacycline (iv)Nuzyra
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Omadacycline (iv) interaction Omadacycline (iv) drug page: uses, dosage & side effects
Omadacycline (oral)Nuzyra
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Omadacycline (oral) interaction Omadacycline (oral) drug page: uses, dosage & side effects
OxytetracyclineTerramycin
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Oxytetracycline interaction
Oxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Oxytetracycline, Phenazopyridine, Sulfamethizole interaction
RetapamulinAltabax, Altargo
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Retapamulin interaction Retapamulin drug page: uses, dosage & side effects
TetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Tetracycline interaction Tetracycline drug page: uses, dosage & side effects
TigecyclineTygacil
Moderate Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.

Read the full Pectin + Tigecycline interaction Tigecycline drug page: uses, dosage & side effects
"phentolamineOraVerse, Rogitine, Ryzumvi › 6-mercaptopurinePurinethol › Ado-trastuzumab EmtansineKadcyla › AbacavirZiagen › Abacavir Sulfate, Dolutegravir, LamivudineTriumeq › Abacavir, LamivudineEpzicom › AbaloparatideTymlos ›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Pectin combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Pectin affects

Every type of medication (drug category) Pectin is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 3 drug categories Pectin interacts with
Digoxin (lanoxin)Lovastatin (mevacor)Tetracycline Antibiotics
Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Monograph

Pectin: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and digestive regularity, but evidence for many supplement claims is limited. It is generally well tolerated, though it can cause gas and bloating, especially when first starting.

Part used
Soluble fiber extracted from fruit (peels and pulp), especially apples and citrus
Common forms
Powder, capsules, gummies, jelly/jam ingredient, modified citrus pectin supplements
People commonly use it for
  • Diarrhea relief
  • Constipation and digestive health
  • Cholesterol support
  • Blood sugar support
  • Appetite and weight management

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Pectin from food and typical supplement amounts is generally well tolerated for most people.

PregnancyLikely Safe

When used in amounts commonly found in foods. Pectin has Generally Recognized as Safe (GRAS) status in the US.

Read the full pregnancy detail
BreastfeedingLikely Safe

When used in amounts commonly found in foods. Pectin has Generally Recognized as Safe (GRAS) status in the US.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Pectin is a type of soluble fiber found naturally in the cell walls of many fruits. It is especially concentrated in apples and the peels of citrus fruits like oranges, lemons, and grapefruit. When mixed with sugar and acid, pectin forms a gel, which is why it is used to thicken jams and jellies.

As a supplement, pectin is sold as a powder, in capsules, and in gummies. A processed form called modified citrus pectin is broken down into smaller pieces and is marketed for different uses than regular pectin. People take pectin mainly as a source of fiber to support digestion, heart health, and blood sugar.

How it works

Pectin is a soluble fiber, meaning it dissolves in water and forms a thick, gel-like substance in the gut. This gel can slow down how fast food and sugar are absorbed, which may help smooth out blood sugar spikes after eating.

The gel can also bind to cholesterol and bile acids in the digestive tract, helping carry some of them out of the body. This is the proposed way pectin may help lower cholesterol. Pectin is also fermented by the bacteria in your colon, which may support gut health.

For modified citrus pectin, researchers believe the smaller molecules may interact with certain proteins in the body, but much of this work is from laboratory and animal studies and is not yet proven in people.

Effectiveness

Does Pectin work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 11 uses evaluated
1 Possibly effective 10 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.
Possibly Effective Hypercholesterolemia
Rating & evidence shown verbatim from Natural Medicines

Most clinical research shows that oral pectin at a dose of 15 grams daily can slightly lower total cholesterol and low-density lipoprotein (LDL) cholesterol levels in patients with hypercholesterolemia.

Also studied for 10 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Colorectal cancer
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral pectin for the prevention of colorectal cancer, there is insufficient reliable information about the clinical effects of pectin for this purpose.

Insufficient Reliable Evidence To Rate Diarrhea
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial in children with persistent diarrhea.

Insufficient Reliable Evidence To Rate Gastroesophageal reflux disease (GERD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial in children with GERD.

Insufficient Reliable Evidence To Rate Impaired glucose tolerance (Prediabetes)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial in patients with impaired glucose tolerance.

Insufficient Reliable Evidence To Rate Irritable bowel syndrome (IBS)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral pectin for IBS, there is insufficient reliable information about the clinical effects of pectin for this purpose.

Insufficient Reliable Evidence To Rate Mercury toxicity
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial in patients with mercury toxicity.

Insufficient Reliable Evidence To Rate Niacin-induced flushing
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial for the prevention or management of niacin-induced flushing.

Insufficient Reliable Evidence To Rate Peptic ulcers
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial for the prevention of peptic ulcers.

Insufficient Reliable Evidence To Rate Prostate cancer
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral pectin is beneficial in patients with prostate cancer.

Insufficient Reliable Evidence To Rate Radiation exposure
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral pectin to minimize exposure to environmental radiation, there is insufficient reliable information about the clinical effects of pectin for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Pectin is widely eaten in foods and is considered safe for most people in normal amounts. As a fiber supplement, the main concern is digestive discomfort, especially if you increase your intake quickly.

Because pectin absorbs water and forms a gel, take it with plenty of fluid to lower the risk of it swelling and causing a blockage, particularly if you have trouble swallowing or have a narrowed digestive tract. People with bowel conditions should talk to a doctor before using fiber supplements.

For pregnancy and breastfeeding, eating fruit and normal dietary pectin is fine. However, concentrated pectin or modified citrus pectin supplements have not been well studied in these groups, so it is best to use caution and check with your doctor or pharmacist first.

Side effects

The most common side effects are related to the digestive system and include gas, bloating, cramping, and loose stools or diarrhea. These often improve as your body adjusts, and starting with a small amount can help.

Allergic reactions are rare but possible, especially in people allergic to the fruit source. Anyone with a known cashew or pistachio allergy may want to be cautious, as some pectin products have been linked to cross-reactions. If you have trouble breathing or swelling after taking pectin, seek medical help.

Pectin: Reported Adverse Effects

Documented safety reports on Pectin from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, pectin seems to be well tolerated.

Most Common Adverse Effects:

Orally: Diarrhea, gas, loose stools, and mild cramps.

Serious Adverse Effects (Rare):

All routes of administration: Allergic reactions, including anaphylaxis, in sensitive individuals.

Reports by condition
Allergic rhinitis (hay fever) Immunologic

Orally and topically, pectin may cause allergic reactions in sensitive individuals. In one case, a 7-year-old boy with a history of oral allergy syndrome after consuming a pectin-containing beverage experienced anaphylaxis after taking a citrus bath containing pectin. Allergy testing confirmed sensitivity to pectin.

  1. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157.
Asthma Pulmonary/Respiratory

The occupational inhalation of pectin dust can cause asthma.

  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6.
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7.
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7.
Diarrhea Gastrointestinal

Orally, pectin alone or in combination with guar gum and insoluble fiber can cause gastrointestinal adverse effects such as mild cramps, diarrhea, gas, and loose stools.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no single official dose for pectin as a supplement, and amounts vary widely between products. The right amount depends on why you are taking it and the specific product.

The best approach is to follow the directions on the product label and start with a lower amount to see how your body responds. Always take pectin with a full glass of water. If you are considering it for a health condition such as high cholesterol or diabetes, talk with your pharmacist or doctor so it can be fit safely into your overall plan.

Pregnancy & Breastfeeding

Pectin & Pregnancy

Likely Safe

When used in amounts commonly found in foods. Pectin has Generally Recognized as Safe (GRAS) status in the US.

  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
Possibly Safe

When used orally in medicinal amounts.

  1. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).

Pectin & Breastfeeding

Likely Safe

When used in amounts commonly found in foods. Pectin has Generally Recognized as Safe (GRAS) status in the US.

  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
Possibly Safe

When used orally in medicinal amounts.

  1. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 11 references that drive our Pectin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Pectin

919 brands in our database make a supplement containing Pectin.

Product directory

Supplement products with Pectin

6,072 products in our database contain Pectin. Open any to see its full ingredient list and every drug interaction we check.

Adult 50+ Probiotic Pearls 1 Billion by Nature's Way Softgel Capsule 30 Softgel(s) View ingredients & interactions Adult Bronson Bears by Bronson Laboratories Gummy Or Jelly 120 Gummie(s) View ingredients & interactions Adult Bronson Bears Vitamin C 120 mg by Bronson Laboratories Gummy Or Jelly 120 Gummie(s) View ingredients & interactions Adult Elderberry Gummies Raspberry Flavor by Nature's Craft Gummy Or Jelly 90 Gummy(ies) View ingredients & interactions Adult Fiber Gummies by Nature's Craft Gummy Or Jelly 60 Gummy(ies) View ingredients & interactions Adult Formula by SmartyPants Gummy Or Jelly 180 Gummy(ies) View ingredients & interactions Adult Formula and Fiber by SmartyPants Gummy Or Jelly 180 Gummy(ies) View ingredients & interactions Adult Gummies Multi Vitamin by Nature's Blend Vitachew Gummy Or Jelly 60 Chew(s) View ingredients & interactions Adult Gummy Calcium 500 mg With 1000 IU Vitamin D3 by Spring Valley Gummy Or Jelly 100 Gummie(s) View ingredients & interactions Adult Gummy D3 1000 IU by Spring Valley Gummy Or Jelly 150 Pectin-Based Gummie(s) View ingredients & interactions Adult Gummy Melatonin 5 mg Natural Strawberry Flavor by Spring Valley Gummy Or Jelly 60 Pectin-Based Gummie(s) View ingredients & interactions Adult Multi by 21st Century VitaJoy Gummies Gummy Or Jelly 120 Gummy(ies) View ingredients & interactions Adult Multi by 21st Century VitaJoy Gummies Gummy Or Jelly 75 Gummy(ies) View ingredients & interactions Adult Multi by 21st Century VitaJoy Gummies Gummy Or Jelly 75 Gummy(ies) View ingredients & interactions Adult Multi Gummies by Meijer Gummy Or Jelly 150 Gummy(ies) View ingredients & interactions Adult Multi Gummies with Essential Vitamins by Puritan's Pride Gummy Or Jelly 75 Gummy(ies) View ingredients & interactions Adult Multi-Gummies with Organic Fruit Blend by Noor Vitamins Gummy Or Jelly 90 Gummie(s) View ingredients & interactions Adult Multi-Vitamin Gummies by Member's Mark Gummy Or Jelly 320 Gummie(s) View ingredients & interactions Adult Multivatamin Gummy by Meijer Gummy Or Jelly 60 Gummy(ies) View ingredients & interactions Adult Multivitamin by Swanson Gummy Or Jelly 60 Gummy(ies) View ingredients & interactions Adult Multivitamin by Solimo Gummy Or Jelly 150 Gummy(ies) View ingredients & interactions Adult Multivitamin by Amazon Basics Gummy Or Jelly 300 Gummy(ies) View ingredients & interactions Adult Multivitamin by Dr Tobias Tablet Or Pill 90 Tablet(s) View ingredients & interactions Adult Multivitamin by Dr. Tobias Tablet Or Pill 90 Tablet(s) View ingredients & interactions
Pharmacist Counseling Corner

Pectin: Common Questions

What is Pectin used for, and does it work?
People use Pectin for many reasons, but the evidence varies by use. According to the Natural Medicines database, there is at least some clinical evidence supporting Pectin for Hypercholesterolemia. For most other uses it has been studied for, the evidence is currently insufficient to rate. See the graded list on this page, and always confirm with your pharmacist or doctor.
Does Pectin interact with prescription medications?
Yes. We list 23 medications with a known interaction with Pectin. Use the checker above to see how Pectin interacts with a specific drug.
How are Pectin interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Pectin with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Pectin interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Pectin used for?
Pectin is a soluble fiber used to thicken jams and jellies in cooking, and as a supplement people take it for digestive regularity, cholesterol support, and blood sugar support. Evidence is strongest for modest cholesterol benefits.
Is Pectin safe to take every day?
For most healthy people, Pectin as a fiber supplement is generally safe to take regularly. Take it with plenty of water and start with a small amount to reduce gas and bloating.
What is the difference between Pectin and modified citrus Pectin?
Regular Pectin is a long-chain fiber used mainly for digestion and as a food gelling agent. Modified citrus Pectin is broken into smaller pieces and is marketed for different uses, but the research behind those claims is still preliminary.
Can Pectin cause side effects?
The most common side effects are gas, bloating, and loose stools, especially when you first start. These usually ease over time, and drinking enough water helps.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Keep exploring

Products that contain Pectin

A rotating sample of real supplements in our database that list Pectin — open any to see its full ingredients and every drug interaction we check.

See all 6,072 products with Pectin →
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