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Dietary supplement

Alpha Yohimbine Ingredients & Drug Interactions

by EA Enhanced

Alpha Yohimbine label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alpha Yohimbine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Alpha Yohimbine is a dietary supplement by EA Enhanced with 1 active ingredient. Its ingredients are commonly taken for fat loss and weight management, bodybuilding and physique support, energy and stimulant effects.Based on those ingredients, 677 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Alpha Yohimbine Hydrochloride. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Alpha Yohimbine by EA Enhanced

Ask about any prescription or over-the-counter medication and we check it for interactions with Alpha Yohimbine by EA Enhanced — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alpha Yohimbine by EA Enhanced

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Alpha Yohimbine by EA Enhanced contains one active ingredient: alpha yohimbine hydrochloride (also called rauwolscine). This is a naturally derived stimulant compound structurally related to yohimbine, an alkaloid from the yohimbe tree.

The capsules also contain several inactive ingredients — rice powder, microcrystalline cellulose (a binding agent), titanium dioxide, FD&C Red #3 and Yellow #6 (color additives), magnesium stearate, and silicon dioxide.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rauwolscine product and its label doesn't state a use — see Rauwolscine's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for alpha yohimbine is insufficient to establish whether it works. Our data shows insufficient reliable evidence to rate its effectiveness for athletic performance, obesity, and sexual arousal.

This doesn't mean it doesn't work — it means human studies haven't yet provided solid proof either way. If you're considering this for any of those purposes, talk with your pharmacist or doctor about what the current research actually supports.

The evidence, ingredient by ingredient Rauwolscine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha Yohimbine is a potent stimulant, and the safety data in humans is limited. The product can affect your heart rate and blood pressure, which is a real concern if you have any heart or blood pressure condition.

Although no adverse effects have been formally reported in oral use, a related compound (yohimbine) has been linked to serious effects including loss of consciousness, paralysis, seizures, and vertigo. Rauwolscine might theoretically cause similar problems.

More common concerns from yohimbine use include anxiety, impulsivity, tremor, dizziness, headache, and flushing. The safety data during pregnancy and breastfeeding is not adequate — the facts advise against use in both.

Side effects, ingredient by ingredient Rauwolscine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rauwolscine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications.
  • For scale: 677 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Alpha Yohimbine, double-check with your pharmacist or doctor if you take any stimulant drugs (ADHD medications, decongestants), blood thinners or antiplatelet drugs (warfarin, aspirin), seizure threshold lowering medications, calcium channel blockers (heart and blood pressure drugs), drugs metabolized by the liver enzyme CYP2D6 (certain antidepressants and heart medications), or clonidine. All of these have documented moderate interactions with the ingredient in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Alpha Yohimbine is a stimulant supplement with documented interactions across a large number of medications and insufficient evidence that it actually works for its marketed purposes. If you take anything for heart health, blood pressure, mental health, seizure control, or any stimulant medication, you need to check this against your exact drugs before considering it.

Talk with your pharmacist or doctor — especially if you have any heart or blood pressure condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha Yohimbine, straight from the product label.

Brand EA Enhanced
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 321421
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha Yohimbine by EA Enhanced, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Alpha Yohimbine Hydrochloride3 mg--

Other ingredients: Rice, Powder, Microcrystalline Cellulose, Titanium Dioxide, FD&C Red #3, FD&C Yellow #6, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, take 1 capsule daily or as directed by your physician.

For maximum results stack with SLIN

Precautions

Warning: This product is only intended to be consumed by healthy individuals 18 years of age or older. Keep out of reach of children.

Consult your physician prior to use if you are pregnant or nursing.

Improper use will not improve results and is not advised. Do not use if safety seal is broken.

California Proposition 65 Warning: This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to: www.P65Warnings.ca.gov/food

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in USA GMP Quality Good Manufacturing Practice Certification

Formulation

Increase thermogenesis Accelerate fat loss Improve energy & mood

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alpha Yohimbine by EA Enhanced label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alpha Yohimbine label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alpha Yohimbine by EA Enhanced

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Alpha Yohimbine Hydrochloride

Interacts with
677 drugs
3 mg per serving Form: Rauwolfia vomitoria

Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout supplements....

Alpha Yohimbine Hydrochloride monograph & interactions

Other (inactive) ingredients: Rice, Powder, Microcrystalline Cellulose, Titanium Dioxide, FD&C Red #3, FD&C Yellow #6, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha Yohimbine by EA Enhanced Drug Interactions

Want to check YOUR meds against Alpha Yohimbine?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
677Drugs
677 Moderate

Ingredients driving the most interactions

Alpha Yohimbine Hydrochloride 677

Individual Drug Interactions

The ingredients in Alpha Yohimbine interact with 677 drugs. Click any drug to see the details.

1 of the 1 ingredient in Alpha Yohimbine interact with drugs. Each result below shows which ingredient is responsible. Alpha Yohimbine Hydrochloride

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha Yohimbine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha Yohimbine Hydrochloride6 drug types · 677 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, rauwolscine may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Rauwolscine is structurally related to yohimbine. In vitro research shows that yohimbine inhibits platelet aggregation.

Likelihood Possible Evidence D
Calcium Channel Blockers

Theoretically, rauwolscine may have additive coronary vasodilatory effects if used with calcium channel blockers.
In vitro, rauwolscine inhibits calcium influx in aortic smooth muscle cells.

Likelihood Possible Evidence D
Clonidine (Catapres)

Theoretically, rauwolscine may inhibit the effects of clonidine.
In animal research, rauwolscine antagonized the effects of clonidine.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, rauwolscine might increase levels of drugs metabolized by CYP2D6.
Rauwolscine is structurally related to yohimbine. In vitro research shows that yohimbine inhibits CYP2D6 enzyme activity.

Likelihood Possible Evidence D
Seizure Threshold Lowering Drugs

Theoretically, taking rauwolscine with seizure threshold lowering drugs might increase the risk of adverse convulsant effects.
In animal research, intraperitoneal rauwolscine lowered the seizure threshold level of the drug metrazol.

Likelihood Possible Evidence D
Stimulant Drugs

Theoretically, taking rauwolscine with stimulant drugs might increase the risk of adverse stimulant effects.
Rauwolscine has demonstrated stimulant effects in animal research.

Likelihood Possible Evidence D
Alpha Yohimbine Hydrochloride full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alpha Yohimbine, from the product label.

EA Enhanced

See all EA Enhanced products
Name
Enhanced Labs
Street Address
P.O. Box 255671
City
Sacramento
State
CA
ZipCode
95865
Web Address
getenhanced.shop
Pharmacist Counseling Corner

Alpha Yohimbine by EA Enhanced: Common Questions

Does Alpha Yohimbine by EA Enhanced interact with any medications?
Yes. Based on its ingredients, Alpha Yohimbine has a known interaction with 677 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha Yohimbine contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does alpha yohimbine actually work for building muscle or losing weight?
The evidence isn't established yet. Our data shows insufficient reliable evidence to rate whether it works for athletic performance or obesity. You'd want to talk with a trainer or doctor about what's actually proven to help.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data is not adequate and the facts advise against it in both pregnancy and breastfeeding. Talk with your OB or midwife if you're thinking about any supplement during pregnancy or while nursing.
What side effects should I watch for?
Most commonly, yohimbine (the related compound) has caused anxiety, tremor, dizziness, headache, and flushing. Serious but rare effects linked to yohimbine include seizures, loss of consciousness, paralysis, and vertigo. Because rauwolscine is structurally similar, it might cause similar problems. Stop and contact a doctor if you feel chest pain, severe dizziness, or any unusual neurological symptoms.
Does this have any fillers or other inactive ingredients?
Yes — the capsules contain rice powder, microcrystalline cellulose, titanium dioxide, FD&C Red #3 and Yellow #6 (color dyes), magnesium stearate, and silicon dioxide. If you have allergies or sensitivities to any of those, check the label or ask your pharmacist.
Why does this interact with so many medications?
Rauwolscine is a potent stimulant that affects multiple systems in your body — heart rate, blood pressure, brain chemistry, blood clotting, and how your liver processes drugs. That's why it can interfere with heart medications, blood thinners, stimulants, seizure drugs, and others. The more systems a supplement touches, the more drugs it can bump into.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Alpha Yohimbine is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha Yohimbine label
Go deeper

The Full Monographs Behind Alpha Yohimbine’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rauwolscine

Interacts with 677 drugs

Rauwolscine (alpha-yohimbine) is a stimulant alkaloid closely related to yohimbine that is marketed mainly in fat-burning and pre-workout supplements. Human evidence for its benefits is very...

Read the full Rauwolscine monograph →
Sources

Sources & How We Checked

Alpha Yohimbine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rauwolscine 28 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Teloken C, Rhoden EL, Sogari P, et al. Therapeutic effects of high dose yohimbine hydrochloride on organic erectile dysfunction. J Urol 1998;159:122-4. PubMed
  4. Jacobsen FM. Fluoxetine-induced sexual dysfunction and an open trial of yohimbine. J Clin Psychiatry 1992;53:119-22.
  5. Hollander E, McCarley A. Yohimbine treatment of sexual side effects induced by serotonin reuptake blockers. J Clin Psychiatry 1992;53:207-9.
  6. Sandler B, Aronson P. Yohimbine-induced cutaneous drug eruption, progressive renal failure, and lupus-like syndrome. Urol 1993;41:343-5. PubMed
  7. Kearney T, Tu N, Haller C. Adverse drug events associated with yohimbine-containing products: a retrospective review of the California Poison Control System reported cases. Ann Pharmacother 2010;44:1022-9. PubMed
  8. VandenBrink, B. M., Foti, R. S., Rock, D. A., Wienkers, L. C., and Wahlstrom, J. L. Prediction of CYP2D6 drug interactions from in vitro data: evidence for substrate-dependent inhibition. Drug Metab Dispos. 2012;40(1):47-53. PubMed
  9. Mustonen, P., Savola, J., and Lassila, R. Atipamezole, an imidazoline-type alpha(2)-adrenoceptor inhibitor, binds to human platelets and inhibits their adrenaline-induced aggregation more effectively than yohimbine. Thromb.Res 8-1-2000;99(3):231-237.
  10. Bagheri, H., Schmitt, L., Berlan, M., and Montastruc, J. L. Effect of 3 weeks treatment with yohimbine on salivary secretion in healthy volunteers and in depressed patients treated with tricyclic antidepressants. Br J Clin Pharmacol 1992;34(6):555-558. PubMed
  11. Swann, A. C., Birnbaum, D., Jagar, A. A., Dougherty, D. M., and Moeller, F. G. Acute yohimbine increases laboratory-measured impulsivity in normal subjects. Biol.Psychiatry 5-15-2005;57(10):1209-1211. PubMed
  12. Adeniyi, A. A., Brindley, G. S., Pryor, J. P., and Ralph, D. J. Yohimbine in the treatment of orgasmic dysfunction. Asian J Androl 2007;9(3):403-407. PubMed
  13. Giampreti, A., Lonati, D., Locatelli, C., Rocchi, L., and Campailla, M. T. Acute neurotoxicity after yohimbine ingestion by a body builder. Clin Toxicol.(Phila) 2009;47(8):827-829. PubMed
  14. Myers, A. and Barrueto, F., Jr. Refractory priapism associated with ingestion of yohimbe extract. J Med Toxicol. 2009;5(4):223-225.
  15. Berlin, I., Crespo-Laumonnier, B., Cournot, A., Landault, C., Aubin, F., Legrand, J. C., and Puech, A. J. The alpha 2-adrenergic receptor antagonist yohimbine inhibits epinephrine-induced platelet aggregation in healthy subjects. Clin Pharmacol.Ther. 199
  16. Swann, A. C. Mechanisms of impulsivity in bipolar disorder and related illness. Epidemiol.Psichiatr.Soc. 2010;19(2):120-130.
  17. Landis, E. and Shore, E. Yohimbine-induced bronchospasm. Chest 1989;96(6):1424. PubMed
  18. Susset, J. G., Tessier, C. D., Wincze, J., Bansal, S., Malhotra, C., and Schwacha, M. G. Effect of yohimbine hydrochloride on erectile impotence: a double-blind study. J Urol. 1989;141(6):1360-1363. PubMed
  19. Braddock, L., Cowen, P. J., Elliott, J. M., Fraser, S., and Stump, K. Binding of yohimbine and imipramine to platelets in depressive illness. Psychol.Med 1986;16(4):765-773. PubMed
  20. Charney, D. S., Heninger, G. R., and Sternberg, D. E. Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci 6-7-1982;30(23):2033-2041.
  21. Boon, N. A., Elliott, J. M., Grahame-Smith, D. G., John-Green, T., and Stump, K. A comparison of alpha 2-adrenoreceptor binding characteristics of intact human platelets identified by [3H]-yohimbine and [3H]- dihydroergocryptine. J Auton.Pharmacol 1983;3
  22. Riley AJ, Goodman R, Kellett JM, and et al. Double blind trial of yohimbine hydrochloride in the treatment of erection inadequacy. Sexual Marital Ther 1989;4(1):17-26. DOI
  23. Wylie KR. Yohimbine and sinusitis. Br J Psychiatry. 1996;169(3):384-5. PubMed
  24. Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA, Rahman HS, Rasedee A. The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial.
  25. Godfraind T, Miller RC, Socrates Lima J. Effects of yohimbine, rauwolscine and corynanthine on contractions and calcium fluxes induced by depolarization and prostaglandin F2 alpha in rat aorta. Br J Pharmacol. 1983;80(1):115-21.
  26. Shepperson NB, Duval N, Massingham R, Langer SZ. Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog. J Pharmacol Exp Ther. 1981;219(2):540-6. DOI
  27. Szabo B, Hedler L, Starke K. Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits. Naunyn Schmiedebergs Arch Pharmacol. 1989;340(6):648-57. PubMed
  28. Doxey JC, Lane AC, Roach AG, Virdee NK. Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch Pharmacol. 1984;325(2):136-44.

See these in context on the Rauwolscine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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