Apple Cider Vinegar Ginger & Lemon Flavor Ingredients & Drug Interactions
by Flora
What is this page for?
First and foremost: checking Apple Cider Vinegar Ginger & Lemon Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Apple Cider Vinegar Ginger & Lemon Flavor is a dietary supplement by Flora with 4 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 2,226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Apple Cider Vinegar, Iron, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Apple Cider Vinegar Ginger & Lemon Flavor by Flora
Ask about any prescription or over-the-counter medication and we check it for interactions with Apple Cider Vinegar Ginger & Lemon Flavor by Flora — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Apple Cider Vinegar Ginger & Lemon Flavor by Flora
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 12 ingredients, including potassium, iron, and several herbs. The herbal components — organic ginger, rhubarb, slippery elm, burdock, apple cider vinegar, sheep sorrel, blessed thistle, and red clover — make up a proprietary blend and herbal decoction.
The product also includes water, kelp, and is flavored with organic apple juice concentrate and natural lemon flavor, which are inactive ingredients.
Does it work?
Strong evidence
The evidence for effectiveness varies. Iron is rated Effective for iron deficiency anemia and several types of anemia.
Ginger is rated Possibly Effective for pregnancy-related nausea and vomiting and dysmenorrhea (period pain). Rhubarb, sorrel, blessed thistle, red clover, and slippery elm all have Insufficient Reliable Evidence to establish their effectiveness for the conditions studied.
Apple cider vinegar's effectiveness for its proposed uses is also Insufficient Reliable Evidence To Rate. Overall, solid evidence supports iron for anemia, while the herbal ingredients lack sufficient research to confirm their benefits.
How safe is it?
Well-documented data
Potassium from food is fine, but supplements require medical guidance, especially if you have kidney disease or take certain blood pressure medications — high potassium levels can cause serious heart problems. Iron is generally well tolerated at recommended doses but can cause nausea, constipation, diarrhea, and abdominal pain; excess iron is toxic.
Ginger is generally well tolerated in typical amounts but may cause heartburn, diarrhea, or a peppery mouth sensation at higher doses. Rhubarb root can cause cramping and shouldn't be used long-term; chronic use may deplete potassium and harm the kidneys.
Apple cider vinegar in food amounts is fine, but large doses can cause low potassium levels and bone loss. Regarding pregnancy: potassium supplements need doctor guidance during pregnancy (dietary potassium is appropriate); ginger is possibly safe for morning sickness but check with your doctor first; rhubarb supplement amounts should be avoided in pregnancy; and limited safety data exist for burdock, sorrel, red clover, and blessed thistle in pregnancy.
For breastfeeding: iron is generally acceptable at appropriate doses; ginger and sorrel are likely safe but ask your provider; rhubarb medicinal use should be avoided; and blessed thistle and red clover lack sufficient safety data.
Meds to double-check
Moderate interaction found
Check before taking this product if you use blood pressure medications (ACE inhibitors, ARBs, potassium-sparing diuretics), blood thinners (warfarin, anticoagulants, antiplatelet drugs), diabetes medications, thyroid medication (levothyroxine), antibiotics (quinolones or tetracyclines), H2-blockers or proton pump inhibitors for acid reflux, or diuretics (water pills). The highest-severity interactions are Moderate and involve potassium levels and bleeding risk.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood pressure medications, blood thinners, diabetes drugs, thyroid medication, or antibiotics, check with your pharmacist before starting this product — the interactions are real and potentially serious. If you have kidney disease or take potassium-affecting medications, this isn't the right choice without medical supervision.
This product may be reasonable for someone looking for ginger and iron without those medication concerns, but the herbal ingredients lack proven benefits.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 10 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Apple Cider Vinegar Ginger & Lemon Flavor, straight from the product label.
| Brand | Flora |
|---|---|
| Barcode (UPC) | 061998681862 |
| Net contents | 3.3 fl. Oz.; 100 mL |
| Market status | On market |
| Date entered into DSLD | Feb 26, 2020 |
| DSLD ID | 213342 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Apple Cider Vinegar Ginger & Lemon Flavor by Flora, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 25 Calorie(s) | -- |
| Total Carbohydrates | 7 Gram(s) | 2% |
| Potassium | 90 mg | 2% |
| Water | 0 NP | -- |
| Iron | 0.2 mg | 1% |
| Total Sugars | 7 Gram(s) | -- |
| organic Ginger | 0 NP | -- |
| organic Kelp | 0 NP | -- |
| Proprietary Blend | 89 Gram(s) | -- |
| organic Rhubarb | 0 NP | -- |
| organic Slippery Elm | 0 NP | -- |
| organic Burdock | 0 NP | -- |
| organic Apple Cider Vinegar | 0 NP | -- |
| Herbal decoction | 0 NP | -- |
| organic Sheep Sorrel | 0 NP | -- |
| organic Blessed Thistle | 0 NP | -- |
| organic Red Clover | 0 NP | -- |
Other ingredients: organic Apple juice concentrate, natural Lemon flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Enjoy the crisp tang of apple cider vinegar combined with the sweet and refreshing citrus flavor of lemon and the spice of ginger. Thoughtfully brewed in small batches, freshly ground organic herbs are water extracted overnight, then blended with organic apple cider vinegar and infused with organic ginger—to support healthy digestion—and the essence of lemon, for an undeniably sweet twist.
Thoughtfully brewed in small batches, freshly ground organic herbs are water extracted overnight, then blended with organic apple cider vinegar and infused with organic ginger—to support healthy digestion—and the essence of lemon,for an undeniably sweet twist. Flora’s Ginger & Lemon Flavor Apple Cider Vinegar is bottled immediately after blending to capture optimum freshness. This wellness shot is uniquely crafted with cleansing herbs found in Flor-Essence, a renowned detox formula. Flora’s Ginger & Lemon Flavor Apple Cider Vinegar will rejuvenate your body and enliven your senses.
Kosher Check
Formulation
Caffeine-free + gluten-free Non-GMO
Vegan
Wellness shot
Certified organic by QAI
Seals/Symbols
Kosher Check
USDA Organic
Non GMO Project Verified nongmoproject.org
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Dietary Supplement
General Statements
Product of Canada
Suggested/Recommended/Usage/Directions
Suggested use: Shake bottle well. Drink 1 bottle (100 mL) before or with a meal.
Storage
Store at room temperature.
Precautions
Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding.
Security sealed for your protection. Do not use if seal is missing or damaged.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Apple Cider Vinegar Ginger & Lemon Flavor by Flora label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Apple Cider Vinegar Ginger & Lemon Flavor by Flora
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size100 mL Dosage formLiquid Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Potassium
Interacts with62 drugs
Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...
Potassium monograph & interactionsIron
Interacts with80 drugs
Iron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventin...
Iron monograph & interactionsProprietary Blend
- › Herbal decoction
Organic Apple Cider Vinegar
Interacts with162 drugs
Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...
Organic Apple Cider Vinegar monograph & interactionsOther (inactive) ingredients: Organic Apple juice concentrate, Natural Lemon flavor. These complete the product’s ingredient list but are not active constituents.
Apple Cider Vinegar Ginger & Lemon Flavor by Flora Drug Interactions
HelloPharmacist Interaction Report
Apple Cider Vinegar Ginger & Lemon Flavor by Flora has documented interactions with medications across multiple categories.
The most serious interaction involves potassium, which carries a Moderate severity rating with blood pressure medications and diuretics that affect potassium levels — these drugs can cause dangerously high potassium levels (hyperkalemia) when combined with this product's potassium content.
Read the full breakdown — every affected drug type, severity by severity
Iron in this product interacts moderately with several antibiotics (quinolones and tetracyclines), thyroid medication (levothyroxine), and other drugs by reducing their absorption — you'd need to separate doses by 2–4 hours depending on the medication. Ginger carries Moderate interactions with blood thinners (warfarin, anticoagulants), diabetes drugs, and some heart medications.
Rhubarb and sheep sorrel (also called sorrel) interact moderately with blood thinners and diuretics, while slippery elm may slow absorption of oral medications generally.
Blessed thistle has Minor interactions with acid-reflux medications (H2-blockers, antacids, proton pump inhibitors), and red clover has Minor interactions with certain blood-thinner and diabetes-related drugs. We could not check water, kelp, or the herbal decoction's full composition.
Altogether, these interactions span 2,203 individual medications.
Your exact medications matter — use the checker on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Apple Cider Vinegar Ginger & Lemon Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Apple Cider Vinegar Ginger & Lemon Flavor interact with 2,226 drugs. Click any drug to see the details.
3 of the 4 ingredients in Apple Cider Vinegar Ginger & Lemon Flavor interact with drugs. Each result below shows which ingredient is responsible. organic Apple Cider Vinegar Iron Potassium
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 1 ingredient. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 2 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + 6-mercaptopurine interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 2 ingredients. Tap an ingredient for the detail:
Organic GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Ado-trastuzumab Emtansine interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Ado-trastuzumab Emtansine interactionAbacavirZiagen
How Abacavir interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 1 ingredient. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 2 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abacavir Sulfate, Dolutegravir, Lamivudine interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 2 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Abacavir, Lamivudine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 5 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abciximab interactionOrganic GingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Ginger + Abciximab interactionOrganic Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Organic Sheep Sorrel + Abciximab interactionOrganic BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Organic Burdock + Abciximab interactionOrganic Red CloverAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Although some laboratory research suggests that red clover may have anticoagulant and antiplatelet activity, clinical research has not shown this effect.
Read the full Organic Red Clover + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 3 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abemaciclib interactionOrganic GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Abemaciclib interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abiraterone interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Abiraterone interactionOrganic GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Abiraterone interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic GingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Abiraterone Acetate interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abiraterone Acetate interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Abiraterone Acetate interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 5 ingredients. Tap an ingredient for the detail:
Organic BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Organic Burdock + Abrocitinib interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Abrocitinib interactionOrganic GingerCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP2C9 substrates.
Read the full Organic Ginger + Abrocitinib interactionOrganic Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Organic Sheep Sorrel + Abrocitinib interactionOrganic Red CloverCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates +1 Minor
Interaction Summary
Theoretically, red clover might increase the levels and clinical effects of drugs metabolized by CYP2C19.
Read the full Organic Red Clover + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 3 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acalabrutinib interactionOrganic GingerP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
Read the full Organic Ginger + Acalabrutinib interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 1 ingredient. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic GingerAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Ginger + Acarbose interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acarbose interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acarbose interactionOrganic Apple Cider VinegarAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Organic Apple Cider Vinegar + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 2 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acebutolol interactionOrganic RhubarbHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 5 ingredients. Tap an ingredient for the detail:
Organic BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Organic Burdock + Acenocoumarol interactionOrganic GingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Organic Ginger + Acenocoumarol interactionOrganic Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Organic Sheep Sorrel + Acenocoumarol interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acenocoumarol interactionOrganic Red CloverAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Although some laboratory research suggests that red clover may have anticoagulant and antiplatelet activity, clinical research has not shown this effect.
Read the full Organic Red Clover + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 1 ingredient. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen interactionOrganic RhubarbNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Organic Rhubarb + Acetaminophen interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 6 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Aspirin interactionOrganic BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Organic Burdock + Acetaminophen, Aspirin interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Aspirin interactionOrganic Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Organic Sheep Sorrel + Acetaminophen, Aspirin interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Aspirin interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 6 ingredients. Tap an ingredient for the detail:
Organic GingerCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Acetaminophen, Aspirin, Caffeine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Aspirin, Caffeine interactionOrganic Sheep SorrelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Organic Sheep Sorrel + Acetaminophen, Aspirin, Caffeine interactionOrganic BurdockAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Organic Burdock + Acetaminophen, Aspirin, Caffeine interactionOrganic RhubarbNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Organic Rhubarb + Acetaminophen, Aspirin, Caffeine interactionOrganic Red CloverAnticoagulant/antiplatelet Drugs, Caffeine +2 Minor
Interaction Summary
Although some laboratory research suggests that red clover may have anticoagulant and antiplatelet activity, clinical research has not shown this effect.
Read the full Organic Red Clover + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Butalbital interactionOrganic RhubarbNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Organic Rhubarb + Acetaminophen, Butalbital interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Butalbital interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Butalbital, Caffeine interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Butalbital, Caffeine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Butalbital, Caffeine interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Acetaminophen, Butalbital, Caffeine, Codeine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Butalbital, Caffeine, Codeine interactionOrganic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Butalbital, Caffeine, Codeine interactionOrganic Red CloverCaffeine, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Butalbital, Codeine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Butalbital, Codeine interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Butalbital, Codeine interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Butalbital, Codeine Phosphate interactionOrganic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Butalbital, Codeine Phosphate interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Butalbital, Codeine Phosphate interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionOrganic Red CloverCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP1A2; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Caffeine, Codeine interactionOrganic GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Acetaminophen, Caffeine, Codeine interactionOrganic RhubarbNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Organic Rhubarb + Acetaminophen, Caffeine, Codeine interactionOrganic Red CloverCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic RhubarbNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Organic Rhubarb + Acetaminophen, Caffeine, Codeine, Salicylamide interactionOrganic GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Organic Ginger + Acetaminophen, Caffeine, Codeine, Salicylamide interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Caffeine, Codeine, Salicylamide interactionOrganic Red CloverCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, red clover might increase levels of drugs metabolized by CYP3A4; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Apple Cider Vinegar Ginger & Lemon Flavor — through 4 ingredients. Tap an ingredient for the detail:
Organic GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Organic Ginger + Acetaminophen, Caffeine, Dihydrocodeine interactionOrganic Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Organic Slippery Elm + Acetaminophen, Caffeine, Dihydrocodeine interactionOrganic RhubarbHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Organic Rhubarb + Acetaminophen, Caffeine, Dihydrocodeine interactionOrganic Red CloverCaffeine, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine; however, a small clinical study found no effect.
Read the full Organic Red Clover + Acetaminophen, Caffeine, Dihydrocodeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Apple Cider Vinegar Ginger & Lemon Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Apple Cider Vinegar
Digoxin (Lanoxin)
Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.
Diuretic Drugs
Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.
Insulin
Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.
Antidiabetes Drugs
Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.
Iron
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)
Iron might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and iron can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, iron containing products.
Bisphosphonates
Iron reduces the absorption of bisphosphonates.
Advise patients that doses of bisphosphonates should be separated by at least two hours from doses of all other medications, including supplements such as iron. Divalent cations, including iron, can decrease absorption of bisphosphonates by forming insoluble complexes in the gastrointestinal tract.
Denosumab (Prolia, Others)
Administration of intravenous iron within one month of denosumab administration might increase the risk of severe hypophosphatemia and hypocalcemia.
A case of severe hypocalcemia (albumin corrected calcium 6.88 mg/dL, ionized calcium 3.68 mg/dL) and hypophosphatemia (<0.5 mg/dL) with respiratory acidosis, QT interval prolongation, and nonsustained ventricular tachycardia was reported in a 76-year-old male who had received an iron polymaltose infusion within 2 weeks of a subcutaneous injection of denosumab. Serum parathyroid hormone was also elevated (348 pg/mL). Subsequent iron infusions with iron polymaltose and ferric carboxymaltose were followed by transient hypophosphatemia, but without hypocalcemia. Additionally, a literature review describes 6 additional cases of hypophosphatemia and hypocalcemia in patients 52-92 years of age who had been administered intravenous iron as either ferric carboxymaltose or iron polymaltose and subcutaneous denosumab within 1-4 weeks of each other.
Dolutegravir (Tivicay)
Iron might decrease dolutegravir levels by reducing its absorption.
Advise patients to take dolutegravir at least 2 hours before or 6 hours after taking iron. Pharmacokinetic research shows that iron can decrease the absorption of dolutegravir from the gastrointestinal tract through chelation. When taken under fasting conditions, a single dose of ferrous fumarate 324 mg orally along with dolutegravir 50 mg reduces overall exposure to dolutegravir by 54%.
Integrase Inhibitors
Theoretically, taking iron along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Iron is a divalent cation. There is concern that iron may decrease the absorption of integrase inhibitors from the gastrointestinal tract through chelation. One pharmacokinetic study shows that iron can decrease blood levels of the specific integrase inhibitor dolutegravir through chelation. Also, other pharmacokinetic research shows that other divalent cations such as calcium can decrease the absorption and levels of some integrase inhibitors through chelation.
Levodopa
Iron might decrease levodopa levels by reducing its absorption.
Advise patients to separate doses of levodopa and iron as much as possible. There is some evidence in healthy people that iron forms chelates with levodopa, reducing the amount of levodopa absorbed by around 50%. The clinical significance of this hasn't been determined.
Levothyroxine (Synthroid, Others)
Iron might decrease levothyroxine levels by reducing its absorption.
Advise patients to separate levothyroxine and iron doses by at least 2 hours. Iron can decrease the absorption and efficacy of levothyroxine by forming insoluble complexes in the gastrointestinal tract.
Methyldopa (Aldomet)
Iron might decrease methyldopa levels by reducing its absorption.
Advise patients to separate methyldopa and iron doses by at least 2 hours. Iron can decrease the absorption of methyldopa from the gastrointestinal tract through chelation, resulting in increases in blood pressure.
Mycophenolate Mofetil (Cellcept)
Theoretically, iron might decrease mycophenolate mofetil levels by reducing its absorption.
Advise patients to take iron 4-6 hours before, or 2 hours after, mycophenolate mofetil. It has been suggested that a decrease of absorption is possible, probably by forming nonabsorbable chelates. However, mycophenolate pharmacokinetics are not affected by iron supplementation in available clinical research.
Penicillamine (Cuprimine, Depen)
Iron might decrease penicillamine levels by reducing its absorption.
Advise patients to separate penicillamine and iron doses by at least 2 hours. Oral iron supplements can reduce absorption of penicillamine by 30% to 70%, probably due to chelate formation. In people with Wilson's disease, this interaction has led to reduced efficacy of penicillamine.
Quinolone Antibiotics
Iron might decrease levels of quinolone antibiotics by reducing their absorption.
Advise patients to separate quinolone antibiotics and iron doses by at least 2 hours. Iron decreases the absorption of quinolones due to formation of insoluble complexes in the gastrointestinal tract.
Tetracycline Antibiotics
Iron might decrease levels of tetracycline antibiotics by reducing their absorption.
Advise patients to take iron at least 2 hours before or 4 hours after tetracycline antibiotics. Concomitant use can decrease absorption of tetracycline antibiotics from the gastrointestinal tract by 50% to 90%.
Chloramphenicol
Theoretically, taking chloramphenicol with iron might reduce the response to iron therapy in iron deficiency anemia.
Chloramphenicol interferes with erythrocyte maturation. However, since chloramphenicol isn't usually taken for prolonged periods, this isn't likely to be clinically significant.
Potassium
Ace Inhibitors (Aceis)
Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Angiotensin Receptor Blockers (Arbs)
Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.
Potassium-Sparing Diuretics
Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.
Brand information
Manufacturer and brand details for Apple Cider Vinegar Ginger & Lemon Flavor, from the product label.
Flora
See all Flora products- Name
- FLORA INC.
- Street Address
- 805 E. BADGER RD.
- City
- LYNDEN
- State
- WA
- ZipCode
- 98264
- Phone Number
- 1.800.446.2110
- Web Address
- www.florahealth.com
Apple Cider Vinegar Ginger & Lemon Flavor by Flora: Common Questions
Does Apple Cider Vinegar Ginger & Lemon Flavor by Flora interact with any medications?
How can one product interact with so many drugs?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Apple Cider Vinegar Ginger & Lemon Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Potassium
Interacts with 62 drugsPotassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...
Read the full Potassium monograph → Herb & supplement monographIron
Interacts with 80 drugsIron is an essential mineral your body needs to make hemoglobin and carry oxygen in the blood. Supplements are mainly useful for treating or preventing iron deficiency and iron-deficiency an...
Read the full Iron monograph → Herb & supplement monographApple Cider Vinegar
Interacts with 162 drugsApple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...
Read the full Apple Cider Vinegar monograph →Sources & How We Checked
Apple Cider Vinegar Ginger & Lemon Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 227 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Potassium 12 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
- Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
- Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
- Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
- Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
- Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
- Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
- Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
- Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
- Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
- Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad
Iron 72 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Bruner AB, Joffe A, Duggan AK, et al. Randomized study of cognitive effects of iron supplementation in non- anaemic iron-deficient adolescent girls. Lancet 1996;348:992-6.
- Ullen H, Augustsson K, Gustavsson C, Steineck G. Supplementary iron intake and risk of cancer: reversed causality? Cancer Lett 1997;114:215-6.
- Reunanen A, Takkunen H, Knekt P, et al. Body iron stores, dietary iron intake and coronary heart disease mortality. J Intern Med 1995;238:223-30. PubMed
- Lund EK, Wharf SG, Fairweather-Tait SJ, Johnson IT. Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers. Am J Clin Nutr 1999;69:250-5.
- Rehman A, Collis CS, Yang M, et al. The effects of iron and vitamin C co-supplementation on oxidative damage to DNA in healthy volunteers. Biochem Biophys Res Comm 1998;246:293-8. PubMed
- Klipstein-Grobusch K, Grobbee DE, den Breeijen JH, et al. Dietary iron and risk of myocardial infarction in the Rotterdam Study. Am J Epidemiol 1999;149:421-8. PubMed
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
- Campbell N, Paddock V, Sundaram R. Alteration of methyldopa absorption, metabolism, and blood pressure control by ferrous sulfate and ferrous gluconate. Clin Pharmacol Ther 1988;43:381-6..
- Schumann K, Borch-Iohnsen B, Hentze MW, Marx JJ. Tolerable upper intakes for dietary iron set by the US Food and Nutrition Board (commentary). Am J Clin Nutr 2002;76:499-500. PubMed
- Tuomainen TP, Punnonen K, Nyyssonen K, Salonen JT. Association between body iron stores and the risk of acute myocardial infarction in men. Circulation 1998;97:1461-6.. PubMed
- Salonen JT, Nyyssonen K, Korpela H, et al. High stored iron levels are associated with excess risk of myocardial infarction in Eastern Finnish men. Circulation 1992;86:803-11.. PubMed
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