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Dietary supplement

Beta Glucan Ingredients & Drug Interactions

by DC

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Beta Glucan is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta 1,3 Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Beta Glucan by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta 1,3 glucan. The tablet also includes inactive ingredients (the fillers and binders that hold it together): calcium carbonate, vegetable cellulose, stearic acid, and vegetable magnesium stearate.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Beta-glucans's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune support and macrophage modulation.
  • We looked for evidence on: Exercise-induced respiratory infections, Lower respiratory tract infections, Upper respiratory tract infection (URTI), Otitis media, Allergic rhinitis (hay fever), Critical illness (trauma) — and 3 related terms.
  • The closest evidence on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Beta-glucans is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Exercise-induced respiratory infections, Lower respiratory tract infections, Otitis media, and more.

Beta 1,3 glucan is rated Likely Effective for two conditions: dyslipidemia (abnormal cholesterol and fat levels in the blood) and coronary heart disease. That means the research supports its use for these purposes, though the evidence isn't 100% conclusive.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from food sources are generally well tolerated. The catch: concentrated supplements like this one don't have as much safety data behind them as whole foods do, so use some caution.

A small number of trial participants using topical beta-glucan creams reported mild skin reactions like contact dermatitis, though these went away on their own. In one trial of children with a serious illness at a very high dose, one patient developed temporary elevations in liver enzymes.

There isn't enough research on supplement doses during breastfeeding to know either way — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check your medications, especially blood pressure drugs and any immunosuppressant medications. Both are Moderate interactions with beta-glucans and worth confirming with your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is well tolerated by most people and backed by solid evidence for cholesterol and heart health. If you take blood pressure medications or immunosuppressants, check with your doctor or pharmacist before starting it — the interactions are real possibilities.

Same goes if you're breastfeeding or have any liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Glucan, straight from the product label.

Brand DC
Net contents 0 Not Present
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 245168
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Glucan by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetable Tablet(s)
Maximum serving Sizes:
1 Vegetable Tablet(s)
IngredientAmount% DV
Beta 1,3 Glucan3 mg--

Other ingredients: Calcium Carbonate, Vegetable Cellulose, Stearic Acid, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Beta 1, 3 Glucan is a unique nutritional substance derived from the cell walls of yeast. Recognized since the 1940's, Bea 1, 3 Glucan has been used in Europe for years. It helps modulate the macrophages - specialized cells in the body - to help support the body's immune system.

Beta 1, 3 Glucan

Formulation

Suitable for vegetarians.

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Supports the immune system

Made in USA

Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Quali Pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 vegetable tablet twice daily.

See for yourself

Beta Glucan by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beta Glucan by DC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetable Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Beta 1,3 Glucan

Interacts with
293 drugs
3 mg per serving Form: Baker's Yeast

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta 1,3 Glucan monograph & interactions

Other (inactive) ingredients: Calcium Carbonate, Vegetable Cellulose, Stearic Acid, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Glucan by DC Drug Interactions

Want to check YOUR meds against Beta Glucan?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Glucan with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta 1,3 Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Beta Glucan, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
Street Address
304 Dee Cee Rd.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Beta Glucan by DC: Common Questions

Does Beta Glucan by DC interact with any medications?
Yes. Based on its ingredients, Beta Glucan has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Glucan contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does beta 1,3 glucan do?
It's an active compound that the research shows can help improve cholesterol levels and support heart health. It also has immune-stimulating effects.
Is this safe to take if I'm on blood pressure medication?
That depends on your specific drug and your pressure readings. Beta-glucans can lower blood pressure, so combining them with your medication could push it too low — talk with your doctor or pharmacist before adding this to your routine.
Can I take this while breastfeeding?
There isn't enough research on supplement doses during breastfeeding to know either way. Check with your doctor or pharmacist before using it.
Does beta 1,3 glucan have side effects?
Oral beta-glucans appear well tolerated in general. Topical forms (creams) can occasionally cause mild skin reactions like contact dermatitis in a small number of people, though those reactions go away on their own.
Is this safe for people taking immunosuppressants?
Beta-glucans stimulate your immune system, which might interfere with how immunosuppressant medications work. Talk with your doctor or pharmacist before taking this product if you're on an immunosuppressant.
Does this product contain any fillers?
Yes — it includes calcium carbonate, vegetable cellulose, stearic acid, and vegetable magnesium stearate as inactive ingredients to hold the tablet together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Glucan is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Glucan label
Sources

Sources & How We Checked

Beta Glucan's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP&reg; for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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