Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Blueberry Ingredients & Drug Interactions

by Herb Xtra

Blueberry label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blueberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Blueberry is a dietary supplement by Herb Xtra with 3 active ingredients. Its ingredients are commonly taken for joint and bone health, skin, hair, and nail support, source of dietary protein.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Blueberry by Herb Xtra

Ask about any prescription or over-the-counter medication and we check it for interactions with Blueberry by Herb Xtra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Blueberry by Herb Xtra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.

Herb Xtra Blueberry is a capsule with 3 ingredients. The active ingredient is blueberry, which provides the anthocyanins and other compounds traditionally associated with the supplement.

The capsule itself is made from gelatin, a protein derived from animal sources. There are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for blueberry's effectiveness is limited in the data we hold. For hypertension, blueberry is rated possibly ineffective.

For age-related cognitive decline, anxiety, athletic performance, cardiovascular disease, and high cholesterol (hyperlipidemia), the evidence is insufficient to rate — meaning there isn't enough reliable research to say whether it works. Gelatin, the capsule material, is rated possibly ineffective for diarrhea and has insufficient evidence for aging skin, beta-thalassemia, uterine fibroids, and brittle nails.

The evidence, ingredient by ingredient Gelatin Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are widely eaten and generally well tolerated. Freeze-dried blueberries in supplement form may cause constipation, diarrhea, nausea, or vomiting — in one clinical trial, a quarter of participants taking 50 grams daily quit in the first week because of stomach upset.

Gelatin is also generally well tolerated as a food, though orally it can cause belching, bloating, and indigestion in some people. Rare allergic reactions to gelatin are possible, including swelling, wheezing, and in severe cases anaphylaxis — particularly in people with known gelatin sensitivity.

For pregnancy, blueberry is rated likely safe; for breastfeeding, the safety of high-dose extracts is unknown, so talk with your doctor or pharmacist. Gelatin is rated likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Gelatin Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take antidiabetes drugs (Minor interaction — may increase low blood sugar risk), flurbiprofen or other nonsteroidal anti-inflammatory drugs that are metabolized similarly (Minor — may raise drug levels), or buspirone (Minor — may raise drug levels). No interactions are documented for gelatin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This blueberry supplement is generally well tolerated as a food, but freeze-dried supplement forms may cause stomach upset in some people. If you take antidiabetes drugs, flurbiprofen, or buspirone, check your exact medications with our tool before starting.

Talk to your pharmacist if you're pregnant, breastfeeding, or have a known gelatin allergy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry, straight from the product label.

Brand Herb Xtra
Barcode (UPC) 777949998698
Net contents 100 Capsule(s); 400 mg
Market status On market
Date entered into DSLD Feb 25, 2013
DSLD ID 17640
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry by Herb Xtra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
777949998698
IngredientAmount% DV
Gelatin0 NP--
Water0 NP--
Blueberry0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Centaurea cyanus

Suggested/Recommended/Usage/Directions

Use: As a Herbal Supplement: 1 capsule 3 times daily with a glass of water.

General

H307100

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blueberry by Herb Xtra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blueberry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blueberry by Herb Xtra

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gelatin

No known
interactions
0 NP per serving

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most heal...

Gelatin monograph & interactions

Water

0 NP per serving

Blueberry

Interacts with
88 drugs
0 NP per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry monograph & interactions
Interaction report

Blueberry by Herb Xtra Drug Interactions

Want to check YOUR meds against Blueberry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Blueberry 88

Individual Drug Interactions

The ingredients in Blueberry interact with 88 drugs. Click any drug to see the details.

1 of the 3 ingredients in Blueberry interact with drugs. Each result below shows which ingredient is responsible. Blueberry

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Blueberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blueberry, from the product label.

Herb Xtra

See all Herb Xtra products
Name
GOURMET NUTRITION F.B. INC.
City
STE-JULIE
State
QUEBEC
ZipCode
J3E 1Z2
Pharmacist Counseling Corner

Blueberry by Herb Xtra: Common Questions

Does Blueberry by Herb Xtra interact with any medications?
Yes. Based on its ingredients, Blueberry has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Blueberries as food are rated likely safe in both pregnancy and breastfeeding, but concentrated supplements haven't been well studied during pregnancy, and the safety of high-dose extracts while breastfeeding is unknown. Talk with your doctor or pharmacist for personalized advice.
What side effects might I experience?
Freeze-dried blueberries in supplement form may cause constipation, diarrhea, nausea, or vomiting. Some people also report belching or bloating from the gelatin capsule. Most people tolerate it well, but if you have a known gelatin allergy, tell your pharmacist — allergic reactions are rare but can be serious.
Does this blueberry supplement actually work?
The evidence in our data is limited. Blueberry is rated possibly ineffective for high blood pressure, and for other conditions like cognitive decline, anxiety, and heart health, there isn't enough reliable research to say whether it works.
Why does the product facts mention 87 interacting medications if blueberry only affects a few drugs?
That number reflects the total of individual medications across all the product's ingredients — in this case, those 87 represent the medications affected by blueberry and gelatin combined. Most of them fall into the three drug types listed: antidiabetes drugs, flurbiprofen, and buspirone.
Is gelatin safe for people who avoid animal products?
Gelatin is derived from animal sources, so this capsule is not suitable for vegetarians or vegans. If that's a concern for you, ask your pharmacist about alternative forms of blueberry supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry label
Go deeper

The Full Monographs Behind Blueberry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gelatin

Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most health uses, the evidence is limited or mixe...

Read the full Gelatin monograph → Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph →
Sources

Sources & How We Checked

Blueberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gelatin 11 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Schwick HG, Heide K. Immunochemistry and immunology of collagen and gelatin. Bibl Haematol 1969;33:111-25. PubMed
  3. Moskowitz RW. Role of collagen hydrolysate in bone and joint disease.Semin Arthritis Rheum 2000;30:87-99. PubMed
  4. Kelso JM. The gelatin story. J Allergy Clin Immunol 1999;103:200-2.
  5. Nakayama T, Aizawa C, Kuno-Sakai H. A clinical analysis of gelatin allergy and determination of its causal relationship to the previous administration of gelatin-containing acellular pertussis vaccine combined with diphtheria and tetanus toxoids. J Allerg PubMed
  6. Sakaguchi M, Inouye S. Anaphylaxis to gelatin-containing rectal suppositories. J Allergy Clin Immunol 2001;108:1033-4. PubMed
  7. PDR Electronic Library. Montvale, NJ: Medical Economics Company, Inc., 2001.
  8. de la Fuente Tornero E, Vega Castro A, de Sierra Hernández PÁ, et al. Kounis syndrome during anesthesia: Presentation of indolent systemic mastocytosis: A case report. A Case Rep. 2017;8(9):226-228. PubMed
  9. Ventura Spagnolo E, Calapai G, Minciullo PL, Mannucci C, Asmundo A, Gangemi S. Lethal anaphylactic reaction to intravenous gelatin in the course of surgery. Am J Ther. 2016;23(6):e1344-e1346. PubMed
  10. Li Y, He H, Yang L, Li X, Li D, Luo S. Therapeutic effect of Colla corii asini on improving anemia and hemoglobin compositions in pregnant women with thalassemia. Int J Hematol. 2016;104(5):559-565. PubMed
  11. Coury JR, Skaggs KF, Marciano GF, et al. Intraoperative Anaphylaxis to the Bovine Flowable Gelatin Matrix: A Report of 2 Cases. JBJS Case Connect 2022;12(1). PubMed

See these in context on the Gelatin monograph →

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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