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Dietary supplement

Burdock Seed Ingredients & Drug Interactions

by Herbalist & Alchemist

Burdock Seed label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Burdock Seed against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Burdock Seed is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Burdock seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Burdock Seed by Herbalist & Alchemist

Ask about any prescription or over-the-counter medication and we check it for interactions with Burdock Seed by Herbalist & Alchemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Burdock Seed by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dried burdock seed extract. Burdock is a root vegetable used in cooking and traditional herbal medicine, and the seed extract is what's in this liquid formula.

The inactive ingredients are ethyl alcohol and distilled water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Burdock's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy skin.
  • We looked for evidence on: Acne, Aging skin, Atopic dermatitis (eczema), Dry skin, Psoriasis, Dermatitis.
  • The closest evidence on file: Burdock is rated "Insufficient Reliable Evidence To Rate" for Acne (Natural Medicines).
  • Also on file: Burdock is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Atopic dermatitis (eczema), Dry skin.

The evidence we hold doesn't establish that burdock seed works for any of the uses commonly claimed for it — acne, aging skin, breast cancer, common cold, or eczema. All of these are rated insufficient reliable evidence to rate, meaning the studies either aren't there or aren't strong enough yet to draw a conclusion.

If you're considering this for one of those reasons, talk it over with your doctor to explore what the current science actually supports.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when eaten as a food, and has a long history of use with few reported side effects. However, human safety data are limited.

Serious allergic reactions including anaphylaxis are rare but possible, and contact dermatitis has been reported, especially after prolonged skin use. One case of liver injury was reported in someone taking an herbal tea containing burdock along with other ingredients, though it's unclear if burdock was the culprit.

Don't use medicinal amounts during pregnancy — safety data aren't there and burdock might affect the uterus. Avoid medicinal use while breastfeeding as well; we don't have enough safety information.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any blood thinners or antiplatelet drugs (including aspirin, warfarin, or clopidogrel), double-check with your doctor or pharmacist before adding this product. The interaction is documented as Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Burdock seed is a traditional herb with a long food history and generally few reported problems in short-term use by healthy adults. The main caution is if you take blood thinners or antiplatelet drugs — check with your doctor or pharmacist first.

If you're pregnant or breastfeeding, talk to your healthcare provider before using medicinal amounts.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Burdock Seed, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056104313
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 83280
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Burdock Seed by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1.5 mL
Servings per container
40
UPC/BARCODE
667056104313
IngredientAmount% DV
dried Burdock seed extract1.5 mL--

Other ingredients: Ethyl Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Arctium lappa

OK

General Statements

Supports healthy skin

Botanical preparation ratio 1:4

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 20-30 drops (1-1.5 mL) in juice or water. Take 3 times per day. Shake well before using.

Precautions

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. BDS-2 1735MO

Seals/Symbols

OK

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Burdock Seed by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Burdock Seed label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Burdock Seed by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container40 Amounts shown are per serving.

Dried Burdock seed extract

Interacts with
122 drugs
1.5 mL per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Dried Burdock seed extract monograph & interactions

Other (inactive) ingredients: Ethyl Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Burdock Seed by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against Burdock Seed?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

dried Burdock seed extract 122

Individual Drug Interactions

The ingredients in Burdock Seed interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Burdock Seed interact with drugs. Each result below shows which ingredient is responsible. dried Burdock seed extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Burdock Seed with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

dried Burdock seed extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
dried Burdock seed extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Burdock Seed, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Burdock Seed by Herbalist & Alchemist: Common Questions

Does Burdock Seed by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, Burdock Seed has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Burdock Seed contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is burdock seed safe to take long-term?
The safety data we hold covers short-term use in healthy adults. Long-term safety hasn't been thoroughly studied, so talk with your doctor or pharmacist about how long you plan to use it.
Can I use this while pregnant or breastfeeding?
No — medicinal amounts of burdock should be avoided during pregnancy because safety data are lacking and it may affect the uterus. The same goes for breastfeeding; we don't have enough information to know it's safe.
What's the risk of an allergic reaction?
Serious allergic reactions like anaphylaxis are rare, but they can happen. Contact dermatitis has been reported, especially after prolonged skin use. If you develop a rash, swelling, or trouble breathing, stop using it and seek medical care.
Does burdock actually work for acne or eczema?
The evidence we hold doesn't show it works for acne, eczema, or the other common uses listed. All are rated insufficient reliable evidence, meaning the science isn't there yet to confirm benefit.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Burdock Seed is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Burdock Seed label
Go deeper

The Full Monographs Behind Burdock Seed’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Burdock Seed's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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