Major interaction on record — check this product against your medications before combining. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Carb Blocker 2 Ingredients & Drug Interactions

by NutriLite

Carb Blocker 2 label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Carb Blocker 2 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Carb Blocker 2 is a dietary supplement by NutriLite with 3 active ingredients. Its ingredients are commonly taken for menopause symptoms (hot flashes), heart and cholesterol health, bone health.Based on those ingredients, 788 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Soybean extract, Parsley concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Carb Blocker 2 by NutriLite

Ask about any prescription or over-the-counter medication and we check it for interactions with Carb Blocker 2 by NutriLite — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Carb Blocker 2 by NutriLite

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Carb Blocker 2 has three active ingredients. Kidney bean extract, soybean extract, and parsley concentrate are designed to work on carbohydrate absorption and blood sugar control.

The tablet also contains several inactive ingredients — microcrystalline cellulose, stearic acid, silicon dioxide, sodium carboxymethylcellulose, methylcellulose, and glycerin — which are fillers and binders that help hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: carbohydrate absorption and starch blocking.
  • We looked for evidence on: Diabetes, Hyperlipidemia, Metabolic syndrome, Obesity, postprandial glucose control, blood sugar management — and 1 related terms.
  • The strongest evidence on file: Soy is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Soy is rated "Possibly Effective" for Hyperlipidemia, Metabolic syndrome.
  • Also on file: Parsley is rated "Insufficient Reliable Evidence To Rate" for Diabetes.

The evidence for this product's ingredients is mixed. Soybean extract has been rated possibly effective for lowering blood sugar (diabetes), cholesterol (hyperlipidemia), bone density (osteoporosis), and blood pressure (hypertension), and possibly effective for diarrhea.

Parsley concentrate, however, has insufficient reliable evidence to rate for any of the conditions we hold data on — urinary tract infections, melasma, osteoarthritis, skin cancer, and insect bites — so we cannot say whether it actually works for carb blocking or any other use. No effectiveness data is on file for kidney bean extract.

The evidence, ingredient by ingredient Soy Parsley

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Soybean extract is well tolerated when eaten as food, but concentrated isoflavone supplements warrant caution — normal food amounts are likely fine, though high-dose supplements should be avoided without medical advice. Common side effects from soy are bloating, constipation, diarrhea, and nausea; allergic reactions including rash and itching can occur in some people.

Parsley concentrate is safe in normal food amounts but may not be safe in large concentrated doses. Very high doses (10 grams or more of parsley's toxic compounds apiole or myristicin) can cause serious problems like hemolytic anemia and low platelet counts.

Rare cases of severe allergic reactions including anaphylaxis have been reported. For pregnancy, soybean extract is rated likely safe but also possibly unsafe — the evidence is mixed — so talk with your doctor or pharmacist for personalized guidance.

Parsley concentrate is rated likely unsafe in pregnancy; normal food amounts are one thing, but medicinal or large amounts may stimulate the uterus. For breastfeeding, soybean extract is likely safe and commonly used, though concentrated supplements have not been well studied.

Lactation data for parsley is not on file.

Side effects, ingredient by ingredient Soy Parsley

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Parsley, Soy.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 788 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before starting if you take monoamine oxidase inhibitors (MAOIs) — a Major interaction with soybean. Then double-check Moderate interactions: blood pressure medications, estrogen, diabetes drugs, diuretics, levothyroxine (thyroid), warfarin or other blood thinners, antiplatelet drugs, caffeine, pentobarbital or other barbiturate sedatives, and sirolimus.

Minor: aspirin, especially if you have a parsley allergy.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you take blood pressure medications, diabetes drugs, blood thinners, thyroid medication, caffeine, or any MAOI, you need to check your specific prescriptions with the tool on this page before starting Carb Blocker 2. If you're pregnant or breastfeeding, talk with your pharmacist or doctor first — the safety picture here is not clear-cut.

People with soy or parsley allergies should avoid this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Carb Blocker 2, straight from the product label.

Brand NutriLite
Barcode (UPC) 10-0193
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 27001
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Qualified Health
Intended target group(s) Adult (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Carb Blocker 2 by NutriLite, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
30
UPC/BARCODE
10-0193
IngredientAmount% DV
Kidney Bean Extract500 mg--
Soybean extract300 mg--
Parsley concentrate30 mg--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Sodium Carboxymethycellulose, Methylcellulose, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

This ephedra-free dietary supplement is made from fermented soy and white kidney bean extracts.

Formula

This ephedra-free dietary supplement is made from fermented soy and white kidney bean extracts.

Halal

General Statements

It provides naturally-sourced, non-stimulating carbohydrate control.

Technical Information Alpha-amylase and alpha-glucosidase are two key digestive enzymes. They break down starches and simple sugars into molecules that can be absorbed by the body - and potentially converted to fat. NUTRILITE Carb Blocker 2 inhibits both enzymes, so fewer sugars and starches are absorbed by the body.

Just load up each convenient and portable sleeve* with your a.m. and p.m. doses, grab it, and go. Days of the week are marked in English, Spanish, and French, so you won't miss a single day. Order your Supplement Center today! *Each sleeve is about the length of a credit card.

Frequently Asked Questions How far in advance of a meal should I take NUTRILITE Carb Blocker 2? For maximum effect, it's best to take Carb Blocker 2 at the beginning of a meal containing carbohydrates. It must be present in the intestine at the same time as the carbohydrates for it to work. How often may I use Carb Blocker 2? Carb Blocker 2 may be used every day as part of a sensible diet, exercise, and supplement program. If I forget to take Carb Blocker 2 before a meal, can I take it during or after a meal? Will it still work? Taking Carb Blocker 2 during a meal is likely to provide some enzyme-inhibiting activity. Taking it after a meal will have little or no effect. Can I take more than 3 tablets for really big meals, like Thanksgiving dinner? What happens if I do? Taking more than 3 tablets of Carb Blocker 2 at once is not recommended. Can I take 9 tablets of NUTRILITE Carb Blocker 2 throughout the day, instead of taking 3 at every meal? For example, 2 tablets for breakfast, 1 for a granola bar and milk snack, 2 for lunch, 2 for dinner, and 2 for late-nite chips and soft drinks? Yes, taking 2 tablets with meals and 1 tablet with carbohydrate-containing snacks if fine. Just don't take more than 9 tablets a day.

More Information Carb Blocker is a natural, ephedra-free dietary supplement that's made from fermented soy and white kidney bean extracts. It can be a great addition to your sensible weight-loss plan that includes eating healthier, smaller portions and exercising more often. Which weight loss supplement is right for you? All the products NUTRILITE offers are designed to help you lead a healthy, active life. Four dietary supplements - SLIMMETRY, Carb Blocker 2, Glucose Health, and Invisifiber - are designed specifically to support your weight-loss efforts. Here's what you need to know to pick the weight-loss supplement that is right for you. It's important to note that all four supplements should be used within the context of a weight management program that consists of a healthy diet and regular physical activity. Choose your supplement based on your weight loss plan! SLIMMETRY: ~ May be beneficial for anyone who is following any type of healthy low-calorie diet (e.g., low fat, low carb, or a balanced diet), because it enhances total weight and fat loss. ~ Should be taken daily as directed (two tablets 20 to 30 minutes before each meal) for best results for the duration of an active dieting phase. ~ Can be used alone or in conjunction with a targeted weight management supplement such as Carb Blocker 2 or Glucose Health. Carb Blocker 2: ~ Lab tests show that Carb Blocker 2 may help block up to 500 carb calories per high-carb meal by helping to limit the absorption of carbs from the small intestine into the blood stream. ~ Is most beneficial for anyone following a low-fat diet that is high in fruits, vegetables, and whole grains, which are all sources of carbohydrates. ~ Can be consumed daily (as needed, based on the carbohydrate content of the meal), and it can be taken in addition to SLIMMETRY. Glucose Health: ~ Glucose Health helps metabolize carbs, fats, and protein, while helping your body use the energy in foods, with an exclusive blend of trace minerals and herbs. ~ Contains chromium picolinate, which may reduce the risk of insulin resistance, and therefore possibly may reduce the risk of type 2 diabetes. ~ The formula also includes vanadium, a trace mineral that research suggests may support the metabolism of cholesterol and triglycerides. Plus, it has a special blend of herbs believed to have a beneficial effect on carbohydrate metabolism. Glucose Health can be taken with other weight management supplements. One small study suggests that chromium picolinate may reduce the risk of insulin resistance, and therefore possibly may reduce the risk of type 2 diabetes. FDA concludes, however that the existence of such a relationship between chromium picolinate and either insulin resistance or type 2 diabetes is highly uncertain. INVISIFIBER: ~ INVISIFIBER is a unique blend of three natural soluble fibers, which can easily be mixed into any beverage or sprinkled onto food without affecting taste or texture, and adds convenient and filling fiber to your diet. ~ Fiber supports normal gastrointestinal health and regularity, which is important when you're following a low-calorie or low-fat diet. ~ INVISIFIBER can be used with other weight management supplements as a healthy way to make sure you're getting enough fiber and to compliment your healthy eating and exercise habits.

It works by inhibiting the activity of digestive enzymes that break down carbohydrates for your body to absorb and store as fat. ~ Laboratory tests show that one 3-tablet serving of Carb Blocker 2 has a powerful carbohydrate-blocking effect. These results suggest that a similar action in humans may help block up to 500 calories when consumed with a high-carbohydrate meal.

Benefits ~ NUTRILITE Carb Blocker 2 is unique as the first supplement to contain fermented soy and white kidney bean extracts that block the absorption of both sugars and starches. ~ You'll still get the benefits of vitamins, minerals, and fiber found in carbohydrate-rich foods. ~ It keeps you feeling fuller, longer. ~ NUTRILITE Carb Blocker 2 is natural.

Block up to 500 calories per high-carb meal. NUTRILITE Carb Blocker 2 is a unique and naturally-sourced way to prevent up to 500 carbohydrate calories from being absorbed when taken with a meal, without depriving your body of vitamins, minerals, and fiber.

Retail Price: $45.05

BEST OF NATURE. BEST OF SCIENCE.

Brand IP Statement(s)

Competitive Information NUTRILITE(R) Carb Blocker 2 is the first supplement to help block absorption of both sugars and starches.

Need help remembering to take your supplements every day, as recommended? The NUTRILITE(R) Supplement Center makes it easy to build a healthy routine.

See how NUTRILITE Carb Blocker 2 stacks up to the competition: NUTRILITE Carb Blocker 2 Health & Nutrition Systems Carb Cutter(R) Kidney Bean Extract (Phaseolus Vulgaris) (mg) 500 500 Soybean Extract (Glycine max L.) (mg) 300 None Parsley Concentrate (leaf, stem) (mg) 30 None Trademarks: Carb Cutter (Hyper Network Solutions, LLC, West Palm Beach, FL)

Nutrilite(R) Carb Blocker 2

SUMMARY Description NUTRILITE(R) Carb Blocker 2 lets you eat the foods you want.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: Adults take one to three tab lets with a carbohydrate-containing meal.

Precautions

Do not exceed 9 tablets per day.

FDA Statement of Identity

ENZYME INHIBITING DIETARY SUPPLEMENT

General

Item #: 100193

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Carb Blocker 2 by NutriLite label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Carb Blocker 2 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Carb Blocker 2 by NutriLite

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Kidney Bean Extract

500 mg per serving

Soybean extract

Interacts with
611 drugs
300 mg per serving

Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones. Eating soy foods as part of a balanced diet is g...

Soybean extract monograph & interactions

Parsley concentrate

Interacts with
443 drugs
30 mg per serving

Parsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a...

Parsley concentrate monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Sodium Carboxymethycellulose, Methylcellulose, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Carb Blocker 2 by NutriLite Drug Interactions

Want to check YOUR meds against Carb Blocker 2?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
788Drugs
9 Major 557 Moderate 222 Minor

Ingredients driving the most interactions

Soybean extract 611
Parsley concentrate 443

Individual Drug Interactions

The ingredients in Carb Blocker 2 interact with 788 drugs. Click any drug to see the details.

2 of the 3 ingredients in Carb Blocker 2 interact with drugs. Each result below shows which ingredient is responsible. Soybean extract Parsley concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Carb Blocker 2 with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Soybean extract12 drug types · 611 drugs

Monoamine Oxidase Inhibitors (Maois)

Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Fermented soy products such as tofu and soy sauce contain tyramine, a naturally occurring chemical that affects blood pressure regulation. The metabolism of tyramine is decreased by MAOIs. Consuming more than 6 mg of tyramine while taking an MAOI can increase the risk of hypertensive crisis. The amount of tyramine in fermented soy products is usually less than 0.6 mg per serving; however, there can be significant variation depending on the specific product used, storage conditions, and length of storage. Storing one brand of tofu for a week can increase tyramine content from 0.23 mg to 4.8 mg per serving. Advise patients taking MAOIs to avoid fermented soy products that contain high amounts of tyramine.

Likelihood Likely Evidence C
Antidiabetes Drugs

Soy can lower blood glucose and have additive effects with antidiabetes drugs.
Clinical research shows that whole soy diets and soy-based meals reduce fasting glucose levels in diabetic and non-diabetic individuals. Also, individuals following a soy-based meal replacement plan seem to require lower doses of sulfonylureas and metformin to manage blood glucose levels when compared with individuals following a diet plan recommended by the American Diabetes Association.

Likelihood Possible Evidence A
Antihypertensive Drugs

Theoretically soy protein may have additive effects with antihypertensive drugs and increase the risk of hypotension.
Although some contradictory research exists, most clinical evidence suggests that consuming soy protein modestly reduces systolic and diastolic blood pressure in individuals with prehypertension or hypertension.

Likelihood Possible Evidence A
Caffeine

Theoretically, soy might reduce the clearance of caffeine.
Soy contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in soy.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, soy might have additive effects when used with diuretic drugs.
Animal research suggests that genistein, a soy isoflavone, increases diuresis within 6 hours of subcutaneous administration in rats. The effects seem to be similar to those of furosemide. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, soy might competitively inhibit the effects of estrogen replacement therapy.
Soy contains phytoestrogens and has been shown to have estrogenic activity in some patients. Although this has not been demonstrated in humans, theoretically, concomitant use of soy with estrogen replacement therapy might reduce the effects of the estrogen replacement therapy.

Likelihood Possible Evidence D
Levothyroxine (Synthroid, Others)

Soy products might reduce the absorption of levothyroxine in some patients.
Preliminary clinical research and a case report suggest that soy-based formulas inhibit the absorption of levothyroxine in infants with congenital hypothyroidism. A levothyroxine dosage increase may be needed for infants with congenital hypothyroidism while using soy-based formulas, and the dose may need to be reduced when soy-based formulas are no longer administered. However, in postmenopausal adults, clinical research shows that taking a single dose of soy extract containing isoflavones 60 mg along with levothyroxine does not affect the oral bioavailability of levothyroxine.

Likelihood Possible Evidence B
Progesterone

Theoretically, combining soy isoflavones with transdermal progesterone may worsen bone density.
Clinical research suggests that significant bone loss may occur in females with osteoporosis who receive a combination of transdermal progesterone with soy milk containing isoflavones when compared with placebo, soy milk alone, or progesterone alone.

Likelihood Possible Evidence A
Tamoxifen (Nolvadex)

Theoretically, estrogenic soy isoflavones might alter the effects of tamoxifen.
Laboratory research suggests that genistein and daidzen, isoflavones from soy, can antagonize the antitumor effects of tamoxifen under some circumstances; however, soy isoflavones might have different effects when used at different doses. A relatively low in vitro concentration of soy isoflavones such as 1 microM/L seems to interfere with tamoxifen, whereas high in vitro concentrations such as those >10 microM/L might actually enhance tamoxifen effects. People on a high-soy diet have soy isoflavones levels ranging from 0.1-6 microM/L. Until more is known, advise patients taking tamoxifen to avoid therapeutic use of soy products.

Likelihood Possible Evidence B
Warfarin (Coumadin)

Theoretically, soy might interfere with the effects of warfarin.
Soy milk has been reported to decrease the international normalized ratio (INR) in a patient taking warfarin. The mechanism of this interaction is not known. However, animal and in vitro research suggests that soy may also inhibit platelet aggregation. Dosing adjustments for warfarin may be necessary.

Likelihood Possible Evidence D
Antibiotic Drugs

Theoretically, antibiotics may decrease the activity of soy isoflavones.
Intestinal bacteria are responsible in part for converting soy isoflavones into their active forms. Antibiotics may decrease the amount of intestinal bacteria and decrease its ability to convert isoflavones.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Soy might modestly induce CYP2C9 enzymes. However, this effect does not seem to be clinically significant.
In vitro research suggests that an unhydrolyzed soy extract might induce CYP2C9. However, the significance of this interaction is likely minimal. In healthy females taking a specific extract of soy (Genistein Soy Complex, Source Naturals), blood levels of losartan, a CYP2C9 substrate, were not significantly affected.

Likelihood Unlikely Evidence D
Soybean extract full monograph & interactions

Parsley concentrate8 drug types · 443 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Animal research suggests that parsley has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that parsley might decrease blood glucose. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Laboratory research suggests that parsley can inhibit CYP1A2.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, parsley might enhance or interfere with the effects of diuretic drugs.
Animal research suggests that parsley seed extract increases urine elimination. Parsley leaf and root might also interfere with diuretic therapy due their purported aquaretic effects.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, parsley might increase the duration of pentobarbital effects.
Animal research suggests that parsley juice prolongs the action of pentobarbital, perhaps by decreasing cytochrome P450 levels. It is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Sirolimus (Rapamune)

Theoretically, large quantities of parsley might increase sirolimus levels.
In one case report, an adult female with a history of kidney transplant presented with elevated blood sirolimus levels, approximately 4-7 times greater than previous measures, after daily consumption of a juice containing approximately 30 grams of parsley for 7 days. Sirolimus levels returned to normal a week after the parsley juice was discontinued.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, large amounts of parsley leaf and root might decrease the effects of warfarin.
Parlsey contains vitamin K.

Likelihood Possible Evidence D
Aspirin

Theoretically, aspirin might increase the severity of allergic reactions to parsley.
In one case, severe urticaria and swelling were reported after taking aspirin with parsley in an individual with a known mild parsley allergy.

Likelihood Unlikely Evidence D
Parsley concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Carb Blocker 2, from the product label.

NutriLite

Phone Number
1-800-253-6500
Pharmacist Counseling Corner

Carb Blocker 2 by NutriLite: Common Questions

Does Carb Blocker 2 by NutriLite interact with any medications?
Yes. Based on its ingredients, Carb Blocker 2 has a known interaction with 788 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Carb Blocker 2 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does soy in this product interact with my estrogen replacement therapy?
Yes, soybean extract is rated Moderate severity. Soy contains phytoestrogens and theoretically may compete with and reduce the effects of estrogen therapy. Talk with your pharmacist or doctor about whether this product is right for you.
I take metformin for diabetes. Can I use this carb blocker?
Both soybean extract and parsley concentrate have documented Moderate interactions with diabetes medications — they can lower blood sugar further and may require dose adjustments. Check with your doctor or pharmacist before starting, and monitor your blood sugar closely.
What are the most common side effects of soy in this product?
The most common side effects from soy are bloating, constipation, diarrhea, and nausea. Allergic reactions like rash and itching are possible in some people.
Is this safe to take while breastfeeding?
Soybean extract is rated likely safe and soy foods are commonly eaten while breastfeeding, but concentrated isoflavone supplements have not been well studied — so we don't have enough data. Talk with your pharmacist or doctor for personalized advice.
Can I take this if I have a soy allergy?
No. This product contains soybean extract, and allergic reactions to soy — including rash, itching, and in rare cases severe reactions — have been reported. Avoid this product if you're allergic to soy.
What is parsley concentrate supposed to do in a carb blocker?
Parsley is included in this product, but we have no reliable evidence that it works for carb blocking, urinary tract infections, melasma, osteoarthritis, skin cancer, or insect bites. Its role here is not established in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Carb Blocker 2 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Carb Blocker 2 label
Go deeper

The Full Monographs Behind Carb Blocker 2’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Soy

Interacts with 611 drugs

Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones. Eating soy foods as part of a balanced diet is generally considered safe for most people...

Read the full Soy monograph → Herb & supplement monograph

Parsley

Interacts with 443 drugs

Parsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...

Read the full Parsley monograph →
Sources

Sources & How We Checked

Carb Blocker 2's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 109 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Soy 88 references
  1. Franke AA, Custer LJ, Tanaka Y. Isoflavones in human breast milk and other biological fluids. Am J Clin Nutr 1998;68:1466-73. PubMed
  2. Albertazzi P, Pansini F, Bonaccorsi G, et al. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998;91:6-11. PubMed
  3. Lu LJ, Anderson KE, Grady JJ, et al. Decreased ovarian hormones during a soya diet: implications for breast cancer prevention. Cancer Res 2000;60:4112-21.
  4. Pino AM, Valladares LE, Palma MA, et al. Dietary isoflavones affect sex hormone-binding globulin levels in postmenopausal women. J Clin Endocrinol Metab 2000;85:2797-800. DOI
  5. Nisley N, Klepser T. Phytoestrogens for the prevention and treatment of osteoporosis. Alt Med Alert 1999 Dec;138-42.
  6. McMichael-Phillips DF, Harding C, Morton M, et al. Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast. Am J Clin Nutr 1998;68:1431S-5S. PubMed
  7. Petrakis NL, Barnes S, King EB, et al. Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women. Cancer Epidemiol Biomarkers Prev 1996;5:785-94.
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