CoQ10 400 mg Ingredients & Drug Interactions
by DC
What is this page for?
First and foremost: checking CoQ10 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ10 400 mg is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ10 400 mg by DC
Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 400 mg by DC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ10 400 mg by DC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: coenzyme Q10, a compound your body makes naturally and uses to produce energy in your cells. The softgel also includes inactive ingredients — rice bran oil, gelatin, vegetable glycerin, and soy lecithin — which help deliver the CoQ10.
Does it work?
Strong evidence
CoQ10 is rated likely effective for treating coenzyme Q10 deficiency itself. For other uses, the evidence is more limited: it's rated possibly effective for fibromyalgia, migraine headaches, congestive heart failure, and diabetic neuropathy.
These ratings mean some clinical research supports benefit, but more study is needed to be certain.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated when taken as directed. In clinical studies, no serious side effects have been reported.
The most common adverse effects are mild gastrointestinal symptoms — appetite suppression, diarrhea, heartburn, nausea, and vomiting — occurring in less than 1% of people, and these can often be minimized by splitting doses above 100 mg. Headache, dizziness, and insomnia have been reported less commonly.
Safety during pregnancy has not been studied enough to know either way, so talk with your doctor for personalized advice. Safety while breastfeeding has also not been well studied — check with your doctor before use.
Meds to double-check
Moderate interaction found
Before you take this, double-check with your pharmacist if you're on warfarin or other blood thinners, chemotherapy drugs (especially alkylating agents like cyclophosphamide), or blood pressure medications. These are the medication types with documented interactions in our data.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 is a good option if you have a documented CoQ10 deficiency, or if you're exploring it for migraine, heart failure, fibromyalgia, or nerve pain under your doctor's guidance. Be cautious if you take warfarin or chemotherapy drugs — run those combinations past your pharmacist first.
Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or on blood pressure medication.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ10 400 mg, straight from the product label.
| Brand | DC |
|---|---|
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 244712 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ10 400 mg by DC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 Calorie(s) | -- |
| Calories from Fat | 10 Calorie(s) | -- |
| Total Fat | 1 Gram(s) | 2% |
| Coenzyme Q10 | 400 mg | -- |
Other ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take 1 softgel daily.
Precautions
Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.
Keep out of reach of children.
Caution: If you are pregnant or nursing do not take this product.
Contains soy ingredients.
Storage
Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).
Formulation
Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.
Contains no artificial flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no wheat, no yeast, no fish, Non-GMO.
Made in USA
Gluten free
Nutritionally supports a healthy heart and gums
Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Quali Pure
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ10 400 mg by DC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ10 400 mg by DC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Coenzyme Q10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q10 monograph & interactionsOther (inactive) ingredients: Rice Bran Oil, Gelatin, Vegetable Glycerin, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.
CoQ10 400 mg by DC Drug Interactions
HelloPharmacist Interaction Report
CoQ10 400 mg by DC can interact with a few important medication types.
The most serious concern is with warfarin (Coumadin), a blood thinner — CoQ10 may reduce how well warfarin prevents blood clots. Four cases of decreased warfarin effectiveness thought to be linked to CoQ10 have been reported, though the effect isn't universal.
If you take warfarin, this is worth a conversation with your pharmacist before starting.
Read the full breakdown — every affected drug type, severity by severity
CoQ10 may also interact with chemotherapy drugs called alkylating agents (such as cyclophosphamide). Because CoQ10 has antioxidant properties, it could theoretically reduce how well these cancer medications work by protecting tumor cells from the oxidative stress these drugs rely on.
Minor interactions are possible with blood pressure medications — CoQ10 can lower blood pressure on its own, so combining it with antihypertensive drugs might lower your pressure more than intended.
Additionally, if you're not on any of these drug types, check your exact medications with the tool on this page to be sure. Altogether, these interactions span 198 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ10 400 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ10 400 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in CoQ10 400 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q10
Hydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Hydroflumethiazide, Reserpine interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Iloprost interactionIndapamideLozide, Lozol
How Indapamide interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Indapamide interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Irbesartan, Hydrochlorothiazide interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Isosorbide Dinitrate, Hydralazine interactionIsradipineDynacirc CR
How Isradipine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Isradipine interactionLabetalolNormodyne, Trandate
How Labetalol interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Labetalol interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Levamlodipine interactionLisinoprilPrinivil, Qbrelis, Zestril
How Lisinopril interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Lisinopril interactionLosartan PotassiumCozaar
How Losartan Potassium interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Losartan Potassium interactionMacitentanOpsumit
How Macitentan interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Macitentan interactionMacitentan, TadalafilOpsynvi
How Macitentan, Tadalafil interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Macitentan, Tadalafil interactionMannitolBronchitol, Osmitrol
How Mannitol interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Mannitol interactionMecamylamineInversine
How Mecamylamine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Mecamylamine interactionMethazolamideNeptazane
How Methazolamide interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Methazolamide interactionMethyclothiazideAquatensen, Enduron
How Methyclothiazide interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Methyclothiazide interactionMethyclothiazide, PargylineEutron
How Methyclothiazide, Pargyline interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Methyclothiazide, Pargyline interactionMethyclothiazide, ReserpineDiutensen-R
How Methyclothiazide, Reserpine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Methyclothiazide, Reserpine interactionMethyldopaAldomet, Methyldopa
How Methyldopa interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Methyldopa interactionMetolazoneDiulo, Mykrox, Zaroxolyn
How Metolazone interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Metolazone interactionMetoprololLopressor, Toprol XL
How Metoprolol interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Metoprolol interactionMinoxidilLoniten, Minoxidil, Rogaine
How Minoxidil interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Minoxidil interactionMoexiprilUnivasc
How Moexipril interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Moexipril interactionMoxonidinePhysiotens
How Moxonidine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Moxonidine interactionNadololCorgard, Nadolol
How Nadolol interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Nadolol interactionNebivololBystolic, Nebilet
How Nebivolol interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Nebivolol interactionNebivolol Hydrochloride, ValsartanByvalson
How Nebivolol Hydrochloride, Valsartan interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Nebivolol Hydrochloride, Valsartan interactionNicardipineCardene, Cardene IV, Cardene SR
How Nicardipine interacts with CoQ10 400 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q10 + Nicardipine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ10 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ10 400 mg, from the product label.
DC
See all DC products- Name
- Dee Cee Laboratories, Inc.
- Street Address
- 304 Dee Cee Rd.
- City
- White House
- State
- TN
- ZipCode
- 37188
CoQ10 400 mg by DC: Common Questions
Does CoQ10 400 mg by DC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is CoQ10, and why would someone take it?
Is CoQ10 safe to take every day?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Does this product have fillers or unnecessary ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ10 400 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ10 400 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ10 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
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- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
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