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Dietary supplement

Cotrienol DG Ingredients & Drug Interactions

by Bronson

Cotrienol DG label
See full label image
Softgel Capsule Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cotrienol DG against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Cotrienol DG is a dietary supplement by Bronson with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, antioxidant support, liver health (fatty liver).Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are DeltaGold(TM) Tocotrienol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cotrienol DG by Bronson

Ask about any prescription or over-the-counter medication and we check it for interactions with Cotrienol DG by Bronson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cotrienol DG by Bronson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Cotrienol DG contains one active ingredient: DeltaGold(TM) Tocotrienol, a form of vitamin E that your body uses as an antioxidant. The softgel also holds inactive ingredients—soy lecithin, rice bran oil, gelatin, purified water, and glycerin—that help deliver and stabilize the tocotrienol.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promotes overall heart health and maintains healthy cholesterol levels.
  • We looked for evidence on: Hypercholesterolemia, Metabolic syndrome, Diabetes, Impaired glucose tolerance (prediabetes), Stroke, Chronic kidney disease (CKD) — and 4 related terms.
  • The strongest evidence on file: Tocotrienols is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Tocotrienols is rated "Possibly Ineffective" for Hypercholesterolemia.
  • Also on file: Tocotrienols is rated "Insufficient Reliable Evidence To Rate" for Stroke, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Chronic kidney disease (CKD).

The evidence for tocotrienols is mixed. For diabetes, the data suggests it's possibly effective.

For high cholesterol (hypercholesterolemia), the evidence points to possibly ineffective. For hair loss (alopecia areata) and breast cancer, we don't hold enough reliable evidence to rate either way.

The evidence, ingredient by ingredient Tocotrienols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tocotrienols are generally well tolerated in studies, though long-term safety at supplement doses isn't firmly established. The data shows no adverse effects were reported in clinical trials of oral tocotrienols.

During pregnancy, there isn't enough safety information, so the data advises against supplemental doses. While breastfeeding, little is known about safety—avoid supplements unless your doctor advises otherwise.

Side effects, ingredient by ingredient Tocotrienols

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tocotrienols.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Blood thinners and antiplatelet drugs (like warfarin, aspirin, or clopidogrel) are the main ones to double-check—tocotrienols may increase bleeding risk with these, though it hasn't happened in humans yet. Use the medication checker on this page to verify your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Cotrienol DG is worth considering if you're interested in diabetes support, but the evidence for cholesterol doesn't favor it. If you take any blood thinners or antiplatelet drugs, talk to your pharmacist before starting.

Pregnancy and breastfeeding are times to check with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cotrienol DG, straight from the product label.

Brand Bronson
Barcode (UPC) 716563275020
Net contents 180 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2013
DSLD ID 25179
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cotrienol DG by Bronson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
UPC/BARCODE
716563275020
IngredientAmount% DV
DeltaGold(TM) Tocotrienol75 mg--

Other ingredients: Soy Lecithin, Rice Bran Oil, Gelatin, purified Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Promotes overall heart health and maintains healthy cholesterol levels

Made in USA

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

DeltaGold(TM) is a trademark of American River Nutrition(TM). U.S. Patent No. 6,350,453.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement for adults, 3 softgels daily, preferably before bedtime or as directed by a health professional.

Formula

Contains Soy.

Precautions

WARNING: Please consult a healthcare professional before taking this product if you are pregnant or nursing.

Keep out of reach of children.

Contains Soy.

Storage

Store at room temperature. Protect from light.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

No. 275B REF 0411

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cotrienol DG by Bronson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cotrienol DG label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cotrienol DG by Bronson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

DeltaGold(TM) Tocotrienol

Interacts with
122 drugs
75 mg per serving Form: D-Gamma-Tocotrienol, Delta Tocotrienol

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early resea...

DeltaGold(TM) Tocotrienol monograph & interactions

Other (inactive) ingredients: Soy Lecithin, Rice Bran Oil, Gelatin, Purified Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cotrienol DG by Bronson Drug Interactions

Want to check YOUR meds against Cotrienol DG?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

DeltaGold(TM) Tocotrienol 122

Individual Drug Interactions

The ingredients in Cotrienol DG interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cotrienol DG interact with drugs. Each result below shows which ingredient is responsible. DeltaGold(TM) Tocotrienol

Each ingredient & the kinds of drugs it affects

For each ingredient in Cotrienol DG with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

DeltaGold(TM) Tocotrienol1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
DeltaGold(TM) Tocotrienol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cotrienol DG, from the product label.

Bronson

Phone Number
1-800-235-3200
Pharmacist Counseling Corner

Cotrienol DG by Bronson: Common Questions

Does Cotrienol DG by Bronson interact with any medications?
Yes. Based on its ingredients, Cotrienol DG has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cotrienol DG contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tocotrienol actually work for high cholesterol?
The data we hold suggests it's possibly ineffective for cholesterol. If lowering cholesterol is your goal, talk with your pharmacist or doctor about other options that have stronger evidence behind them.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking first. Tocotrienols may increase bleeding risk when combined with blood thinners, though it hasn't been seen in humans yet. Use the medication checker on this page or ask your pharmacist about your specific drug.
Is it safe to take while pregnant?
No, there isn't enough safety information. The data advises against supplemental tocotrienol doses during pregnancy. Talk with your doctor or pharmacist for personalized guidance.
What side effects should I watch for?
Oral tocotrienols appear well tolerated and no adverse effects were reported in clinical trials. The only side effect on record is mild itching when applied as a cream to skin, not from taking it by mouth.
Is this the same as regular vitamin E?
Tocotrienols are a form of vitamin E, but they're not the same as the more common form called tocopherols. This product specifically contains tocotrienols (DeltaGold(TM)).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cotrienol DG is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cotrienol DG label
Go deeper

The Full Monographs Behind Cotrienol DG’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph →
Sources

Sources & How We Checked

Cotrienol DG's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tocotrienols 4 references
  1. Mensink RP, van Houwelingen AC, Kromhout D, Hornstra G. A vitamin E concentrate rich in tocotrienols had no effect on serum lipids, lipoproteins, or platelet function in men with mildly elevated serum lipid concentrations. Am J Clin Nutr 1999;69:213-9. PubMed
  2. Baumann LS, Spencer JS. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatol Surg 1999;25:311-5. PubMed
  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
  4. Slivka A, Rink C, Paoletto D, Sen CK. Platelet function in stroke/transient ischemic attack patients treated with tocotrienol. FASEB J. 2020;34(9):11838-11843. PubMed

See these in context on the Tocotrienols monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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