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Dietary supplement

Eldermune Chewables Ingredients & Drug Interactions

by Allergy Research Group

Eldermune Chewables label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eldermune Chewables against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eldermune Chewables is a dietary supplement by Allergy Research Group with 2 active ingredients. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 394 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bilberry, Powder, Elderberry Juice Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eldermune Chewables by Allergy Research Group

Ask about any prescription or over-the-counter medication and we check it for interactions with Eldermune Chewables by Allergy Research Group — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Eldermune Chewables by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.
  • “Eldermune Elderberry Complex” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

Eldermune Chewables contains 2 active ingredients: bilberry powder and an elderberry juice concentrate complex. Bilberry is a berry rich in anthocyanidins, plant compounds with antioxidant properties.

Elderberry juice concentrate comes from ripe elderberry fruit and is prepared by cooking to remove any naturally occurring toxins. The product also includes several inactive ingredients — sorbitol, xylitol, mannitol, honey powder, natural berry flavor, lecithin, and others — that serve as sweeteners, binders, and flavorings in the chewable tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support immune and digestive health.
  • We looked for evidence on: Respiratory tract infections, Upper respiratory tract infection (URTI), Lower respiratory tract infections, Rhinosinusitis, Constipation, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The closest evidence on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Ulcerative colitis (Natural Medicines).
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Irritable bowel syndrome (IBS).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections, Constipation, Rhinosinusitis.

The evidence for what these ingredients actually do is limited. For bilberry, night vision support is rated possibly ineffective, while age-related cognitive decline, macular degeneration, atherosclerosis, high cholesterol, and chronic venous insufficiency all lack enough reliable evidence to rate.

For elderberry, the data we hold shows insufficient evidence to rate it for hay fever, heart disease, chronic fatigue, lung disease, brain function, or respiratory infections. In short, the evidence backing either ingredient for any specific use isn't well established in our data.

The evidence, ingredient by ingredient Bilberry Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bilberry fruit from food sources is generally safe, but supplement safety data is limited and long-term safety isn't well studied. The most common side effects are dark-colored stools, flatulence, and stomach discomfort.

Your tongue and teeth may temporarily stain dark blue or black. Elderberry prepared from ripe, cooked fruit is generally well tolerated.

Raw or unripe berries, seeds, leaves, and bark can contain compounds that cause nausea, vomiting, diarrhea, weakness, and dizziness — but cooking eliminates this toxin. There's one case report of autoimmune hepatitis linked to long-term elderberry use in a patient with underlying autoimmune disease, though a direct causal link wasn't established.

Side effects, ingredient by ingredient Bilberry Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bilberry, Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 394 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Eldermune Chewables, check with your pharmacist if you take blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel) — bilberry may increase bleeding risk. Also double-check if you're on diabetes medication, erlotinib or other cancer drugs, or immunosuppressant drugs used after transplants or for autoimmune conditions.

Elderberry may also interact with pazopanib.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is not well studied for its intended effects. If you take blood thinners, diabetes medications, cancer drugs, or immunosuppressants, you'll want to check with your pharmacist before starting it.

Pregnancy and breastfeeding safety data for elderberry are limited — talk with your doctor or pharmacist for personalized advice if you're pregnant, trying to conceive, or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eldermune Chewables, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947783003
Net contents 60 Chewable Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 317589
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eldermune Chewables by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
UPC/BARCODE
713947783003
IngredientAmount% DV
Bilberry, Powder20 mg--
Eldermune Elderberry Complex250 mg--
Elderberry Juice Concentrate0 NP--

Other ingredients: Sorbitol, Xylitol, Mannitol, Honey, Powder, natural Mixed Berry flavor, Sunflower Lecithin, Nu-Flow, Rice extract, Rice, Gum Arabic, Sunflower Oil, Sunfiber, Silicon Dioxide, Malic Acid, Stevia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Eldermune Chewables Eldermune Chewables support immune and digestive health in children and adults. Contains a 65:1 black elderberry juice concentrate standardized to a minimum 3% polyphenols, Sunfiber low-FODMAP friendly prebiotic fiber, and Bilberry fruit powder.

Elderberry 65:1 Concentrate with Sunfiber

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, chew or suck 1 tablet one to four times daily with or without meals, or as directed by a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Ribus NewFLOW and Nu-MAG are a trademark of RIBUS, Inc. ElderMune Eldermune is a trademark of Innovative Natural Solutions LLC(INS Farms). Sunfiber is a registered trademark of Taiyo International, Inc.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eldermune Chewables by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eldermune Chewables label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eldermune Chewables by Allergy Research Group

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bilberry, Powder

Interacts with
275 drugs
20 mg per serving

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

Bilberry, Powder monograph & interactions

Eldermune Elderberry Complex

250 mg per serving

Other (inactive) ingredients: Sorbitol, Xylitol, Mannitol, Honey, Powder, Natural Mixed Berry flavor, Sunflower Lecithin, Nu-Flow, Rice extract, Rice, Gum Arabic, Sunflower Oil, Sunfiber, Silicon Dioxide, Malic Acid, Stevia. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eldermune Chewables by Allergy Research Group Drug Interactions

Want to check YOUR meds against Eldermune Chewables?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
394Drugs
394 Moderate

Ingredients driving the most interactions

Bilberry, Powder 275
Elderberry Juice Concentrate 121

Individual Drug Interactions

The ingredients in Eldermune Chewables interact with 394 drugs. Click any drug to see the details.

2 of the 2 ingredients in Eldermune Chewables interact with drugs. Each result below shows which ingredient is responsible. Bilberry, Powder Elderberry Juice Concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Eldermune Chewables with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bilberry, Powder4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Bilberry, Powder full monograph & interactions

Elderberry Juice Concentrate2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry Juice Concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eldermune Chewables, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
South Salt Lake
State
UT
ZipCode
84115
Phone Number
800.545.9960
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

Eldermune Chewables by Allergy Research Group: Common Questions

Does Eldermune Chewables by Allergy Research Group interact with any medications?
Yes. Based on its ingredients, Eldermune Chewables has a known interaction with 394 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eldermune Chewables contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Bilberry is rated likely safe in pregnancy and lactation. Elderberry safety data during pregnancy and breastfeeding is insufficient — the facts advise against elderberry supplements in both, so you should talk with your doctor or pharmacist before using this product if you're pregnant, trying to conceive, or nursing.
What are the most common side effects?
Bilberry most commonly causes dark-colored stools, flatulence, and stomach discomfort. Your tongue may also temporarily stain dark blue or black, and in rare cases your teeth. Elderberry from ripe, cooked fruit is well tolerated, but raw or unripe berries can cause nausea, vomiting, and diarrhea.
Does this product actually work for improving vision or immunity?
The evidence isn't established. Bilberry for night vision is rated possibly ineffective. For everything else — cognitive decline, age-related macular degeneration, and all the uses tested for elderberry — we don't have enough reliable evidence to say whether it works.
Why does the label say to avoid supplements if bilberry is in food?
Bilberry fruit as food is safe, but concentrated supplement doses haven't been studied long-term and their safety isn't well understood. The caution is about high-dose supplements, not regular food amounts.
Is there any ingredient in here I should know about?
The two active ingredients are bilberry powder and elderberry juice concentrate — both from ripe, cooked fruit where properly prepared. The rest are inactive ingredients (sweeteners, binders, flavorings) like sorbitol, mannitol, and honey powder.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eldermune Chewables is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eldermune Chewables label
Go deeper

The Full Monographs Behind Eldermune Chewables’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph → Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph →
Sources

Sources & How We Checked

Eldermune Chewables's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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