Interactions on record — worth a quick check against your medications. Based on 5 of 8 ingredients. Check your meds →
Dietary supplement

Fermented Mushroom Complete 1200 mg Ingredients & Drug Interactions

by Solaray

Fermented Mushroom Complete 1200 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fermented Mushroom Complete 1200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fermented Mushroom Complete 1200 mg is a dietary supplement by Solaray with 8 active ingredients. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 502 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Reishi Mushroom, Fermented, Chaga Mushroom, Fermented, Lion's Mane Mushroom, Fermented. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fermented Mushroom Complete 1200 mg by Solaray

Ask about any prescription or over-the-counter medication and we check it for interactions with Fermented Mushroom Complete 1200 mg by Solaray — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fermented Mushroom Complete 1200 mg by Solaray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 8 of its 8 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Fermented Mushroom Complete contains 8 active ingredients, all mushroom species: chaga, lion's mane, maitake, reishi, royal agaricus, shiitake, turkey tail, and cordyceps — each fermented to break down their cell walls and make them easier for your body to absorb. These mushrooms have been used in traditional medicine for centuries, and modern research has focused on their polysaccharides and beta-glucans — the compounds that may support immune function and overall wellness.

The capsule itself is made from vegetable cellulose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: immune support.
  • We looked for evidence on: Allergic rhinitis (hay fever), Asthma, Chronic obstructive pulmonary disease (COPD), Coronavirus disease 2019 (COVID-19), HIV/AIDS, General immune function — and 2 related terms.
  • The closest evidence on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever) (Natural Medicines).
  • Also on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for HIV/AIDS, Coronavirus disease 2019 (COVID-19).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Asthma, Chronic obstructive pulmonary disease (COPD).

The evidence isn't strong yet for any of these mushrooms. For chaga, lion's mane, maitake, reishi, royal agaricus, shiitake, turkey tail, and cordyceps, we don't have enough reliable research to say whether they work for conditions like heart disease, diabetes, cognitive support, allergies, fatigue, or athletic performance.

Most carry a rating of insufficient evidence — meaning studies are either too small, too few, or not well designed enough to draw solid conclusions. The one exception is cordyceps for athletic performance, which is rated possibly ineffective based on available research.

The evidence, ingredient by ingredient Chaga Lion's Mane Mushroom Maitake Mushroom Reishi Mushroom Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These mushrooms are generally well tolerated as foods and teas, but long-term supplement safety hasn't been thoroughly studied. The most common side effects from lion's mane, maitake, and cordyceps are mild gastrointestinal issues — nausea, diarrhea, abdominal discomfort, and constipation — though these were uncommon in trials and sometimes improved when taken with food.

Chaga contains high amounts of oxalate; in rare cases, excessive consumption has been linked to kidney damage. One case report suggests cordyceps may have caused liver inflammation, though it's unclear whether cordyceps or a contaminant was responsible.

For pregnancy and breastfeeding, the safety data for all checked ingredients advises against use — there isn't enough information to know either way, so talk with your doctor or pharmacist before considering this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Chaga Lion's Mane Mushroom Maitake Mushroom Reishi Mushroom Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Maitake Mushroom, Cordyceps, Reishi Mushroom, Chaga, Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 502 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications if you're on blood thinners like warfarin or antiplatelet drugs like aspirin or clopidogrel (Moderate risk from chaga, lion's mane, maitake, and cordyceps). Also verify your antidiabetes medications — metformin, sulfonylureas, insulin, and others — as all four checked mushrooms may lower blood sugar further (Moderate).

If you take blood pressure medication, blood pressure could drop further with maitake (Moderate). Immunosuppressants used after transplant or for autoimmune disease may not work as well with chaga, lion's mane, or cordyceps (Moderate).

Testosterone supplements or treatments should also be reviewed with cordyceps in the mix (Minor). Use the medication checker on this page to search your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you're taking blood thinners, antidiabetes medications, blood pressure drugs, or immunosuppressants, check with your pharmacist before starting this product — the interaction risks are real, even though they haven't been seen in people yet. Otherwise, these mushrooms are generally mild and well tolerated, though the evidence for what they actually do isn't established.

If you're interested in trying them, do so with clear eyes about the limits of the science.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fermented Mushroom Complete 1200 mg, straight from the product label.

Brand Solaray
Barcode (UPC) 076280953794
Net contents 60 VegCap(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 325978
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fermented Mushroom Complete 1200 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 VegCap(s)
Maximum serving Sizes:
2 VegCap(s)
Servings per container
30
UPC/BARCODE
076280953794
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Chaga Mushroom, Fermented150 mg--
Lion's Mane Mushroom, Fermented150 mg--
Maitake Mushroom, Fermented150 mg--
Reishi Mushroom, Fermented150 mg--
Royal Agaricus Mushroom, Fermented150 mg--
Shiitake Mushroom, Fermented150 mg--
Turkey Tail Mushroom, Fermented150 mg--
Cordyceps Mushroom, Fermented150 mg--

Other ingredients: Vegetable Cellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solaray Est. 1973

Formula

Fermented Mushroom Complete 1200 mg per serving 8 Mushroom Blend

Formulation

+ Immune Support

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Non GMO Project Verified nongmoproject.org Lab Verified

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 2 VegCaps daily with a meal or glass of water.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

100% PCR Bottles

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fermented Mushroom Complete 1200 mg by Solaray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fermented Mushroom Complete 1200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fermented Mushroom Complete 1200 mg by Solaray

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 VegCap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chaga Mushroom, Fermented

Interacts with
327 drugs
150 mg per serving Form: Inonotus obliquus, Fermented

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Chaga Mushroom, Fermented monograph & interactions

Lion's Mane Mushroom, Fermented

Interacts with
327 drugs
150 mg per serving Form: Hericium erinaceus, Fermented

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Mushroom, Fermented monograph & interactions

Maitake Mushroom, Fermented

Interacts with
260 drugs
150 mg per serving Form: Grifola frondosa, Fermented

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and bl...

Maitake Mushroom, Fermented monograph & interactions

Reishi Mushroom, Fermented

Interacts with
375 drugs
150 mg per serving Form: Ganoderma lucidum, Fermented

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits...

Reishi Mushroom, Fermented monograph & interactions

Royal Agaricus Mushroom, Fermented

150 mg per serving Form: Oats, Agaricus blazei, Fermented

Shiitake Mushroom, Fermented

150 mg per serving Form: Lentinula edodes, Fermented

Turkey Tail Mushroom, Fermented

150 mg per serving Form: Coriolus versicolor, Fermented

Cordyceps Mushroom, Fermented

Interacts with
249 drugs
150 mg per serving Form: Cordyceps militaris, Fermented

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps Mushroom, Fermented monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fermented Mushroom Complete 1200 mg by Solaray Drug Interactions

Want to check YOUR meds against Fermented Mushroom Complete 1200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
502Drugs
494 Moderate 8 Minor

Ingredients driving the most interactions

Reishi Mushroom, Fermented 375
Chaga Mushroom, Fermented 327
Lion's Mane Mushroom, Fermented 327
Maitake Mushroom, Fermented 260
Cordyceps Mushroom, Fermented 249

Individual Drug Interactions

The ingredients in Fermented Mushroom Complete 1200 mg interact with 502 drugs. Click any drug to see the details.

5 of the 8 ingredients in Fermented Mushroom Complete 1200 mg interact with drugs. Each result below shows which ingredient is responsible. Reishi Mushroom, Fermented Chaga Mushroom, Fermented Lion's Mane Mushroom, Fermented Maitake Mushroom, Fermented Cordyceps Mushroom, Fermented

Each ingredient & the kinds of drugs it affects

For each ingredient in Fermented Mushroom Complete 1200 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Reishi Mushroom, Fermented3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
Reishi Mushroom, Fermented full monograph & interactions

Chaga Mushroom, Fermented3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga Mushroom, Fermented full monograph & interactions

Lion's Mane Mushroom, Fermented3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Mushroom, Fermented full monograph & interactions

Maitake Mushroom, Fermented3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
Maitake Mushroom, Fermented full monograph & interactions

Cordyceps Mushroom, Fermented3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps Mushroom, Fermented full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fermented Mushroom Complete 1200 mg, from the product label.

Solaray

See all Solaray products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Fermented Mushroom Complete 1200 mg by Solaray: Common Questions

Does Fermented Mushroom Complete 1200 mg by Solaray interact with any medications?
Yes. Based on its ingredients, Fermented Mushroom Complete 1200 mg has a known interaction with 502 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fermented Mushroom Complete 1200 mg contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm on warfarin or another blood thinner?
Not without checking with your pharmacist first. Chaga, lion's mane, maitake, and cordyceps all carry moderate-risk interactions with blood thinners — they may theoretically increase bleeding risk. There's even a case report of a patient on warfarin whose blood-thinning level rose after taking maitake. You need to verify your specific medication before starting.
What side effects should I watch for?
Gastrointestinal discomfort is the most common — nausea, diarrhea, abdominal discomfort, or constipation from lion's mane, maitake, or cordyceps. These were uncommon in trials and sometimes improved when taken with food. Skin rash has been reported rarely. If you take a lot of chaga over time, there's a theoretical risk of kidney problems because it's high in oxalate.
Can I take this if I'm pregnant or breastfeeding?
The safety data we have advises against it — there simply isn't enough information to know whether it's safe for you or your baby. Talk with your doctor or pharmacist about whether this product is right for you before you're pregnant, during pregnancy, or while nursing.
Does this actually work for anything — like boosting energy or immune support?
We don't have strong evidence yet. For all eight mushrooms in this product, the research is too limited or not solid enough to say whether they work for heart health, diabetes, brain function, fatigue, allergies, or anything else. That doesn't mean they don't work — just that we can't prove it from the studies we have.
What are the inactive ingredients?
Only vegetable cellulose, which is the capsule itself. There are no other fillers or binders listed.
Can I take this with my blood sugar medication?
Not without talking to your pharmacist. Chaga, lion's mane, and maitake may all lower blood sugar further, which raises your risk of low blood sugar (hypoglycemia). Your doctor might need to adjust your diabetes medication dose if you start this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fermented Mushroom Complete 1200 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fermented Mushroom Complete 1200 mg label
Go deeper

The Full Monographs Behind Fermented Mushroom Complete 1200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph → Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph → Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Fermented Mushroom Complete 1200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 54 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Maitake Mushroom 8 references
  1. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol (Tokyo) 1989;35:91-4. PubMed
  2. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol (Tokyo) 1987;33:341-6. PubMed
  3. Konno S, Tortorelis DG, Fullerton SA, et al. A possible hypoglycaemic effect of maitake mushroom on Type 2 diabetic patients. Diabet Med 2001;18:1010. PubMed
  4. Chen JT, Tominaga K, Sato Y, et al. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate. J Altern Compl
  5. Hanselin MR, Vande Griend JP, Linnebur SA. INR elevation with maitake extract in combination with warfarin. Ann Pharmacother 2010;44:223-4. PubMed
  6. Talpur, N. A., Echard, B. W., Fan, A. Y., Jaffari, O., Bagchi, D., and Preuss, H. G. Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strains. Mol.Cell Biochem. 2002;237(1-2):129-136. PubMed
  7. Deng, G., Lin, H., Seidman, A., Fornier, M., D'Andrea, G., Wesa, K., Yeung, S., Cunningham-Rundles, S., Vickers, A. J., and Cassileth, B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: i
  8. Wesa KM, Cunningham-Rundles S, Klimek VM, et al. Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study. Cancer Immunol Immunother 2015;64(2):237-47. PubMed

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Cordyceps 14 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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