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Dietary supplement

Gammadyn Mn-Co Ingredients & Drug Interactions

by UNDA Gammadyn

Gammadyn Mn-Co label
See full label image
Liquid Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gammadyn Mn-Co against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gammadyn Mn-Co is a dietary supplement by UNDA Gammadyn with 2 active ingredients. Its ingredients are commonly taken for bone health support, antioxidant and enzyme support, filling dietary gaps.Based on those ingredients, 83 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Manganese. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Gammadyn Mn-Co by UNDA Gammadyn

Ask about any prescription or over-the-counter medication and we check it for interactions with Gammadyn Mn-Co by UNDA Gammadyn — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Gammadyn Mn-Co by UNDA Gammadyn

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

UNDA Gammadyn Mn-Co is a liquid supplement with two active ingredients: manganese and cobalt. Manganese is an essential mineral your body needs in small amounts for bone health, metabolism, and nervous system function.

Cobalt is a component of vitamin B12, though inorganic cobalt supplements (like those in this product) are not a proven source of B12 benefit. The product also contains purified water and glucose as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Manganese and cobalt nutrient supplementation.
  • We looked for evidence on: Manganese deficiency, Wound healing, Bone metabolism, Connective tissue support.
  • The strongest evidence on file: Manganese is rated "Effective" for Manganese deficiency (Natural Medicines).
  • Also on file: Manganese is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

Manganese is effective for treating manganese deficiency. For other uses — hay fever, osteoporosis, COPD, weight management, and osteoarthritis — the evidence isn't established in the data we hold.

Cobalt has no effectiveness ratings on file for us.

The evidence, ingredient by ingredient Manganese Cobalt

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Manganese is generally well tolerated in normal dietary amounts, but high-dose supplements carry real risks. At high doses, manganese can cause serious neurological damage, including Parkinson-like symptoms and neurotoxicity.

One documented case involved irreversible Parkinson disease possibly linked to 100 mg daily for 2-4 years. High doses can also damage the liver, causing cirrhosis and fatty liver disease.

Cobalt should be approached with caution. Taken orally in small amounts for up to 90 days it seems okay, but long-term or high-dose use may cause heart problems, hearing loss, and vision loss — these are rare but serious.

Cobalt supplements are not recommended during pregnancy because of toxicity concerns. For breastfeeding, the data is unclear, but most sources advise avoiding them.

Side effects, ingredient by ingredient Manganese Cobalt

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Manganese.
  • The most serious interaction on file is rated Moderate.
  • For scale: 83 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before starting if you take antipsychotic drugs (risk of manganese toxicity and neurological effects — Moderate severity), quinolone antibiotics like ciprofloxacin (reduced absorption — Moderate severity), or tetracycline antibiotics like doxycycline (reduced absorption — Moderate severity). No interactions are documented for cobalt in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for manganese deficiency when prescribed or advised by your doctor. If you take antipsychotics or quinolone or tetracycline antibiotics, you need to check with your doctor or pharmacist before starting it — manganese can interfere with how those drugs work or raise toxicity risk.

Because high-dose manganese and cobalt carry serious neurological and cardiac risks, this isn't a supplement to take casually; discuss it with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gammadyn Mn-Co, straight from the product label.

Brand UNDA Gammadyn
Barcode (UPC) 883196313501
Net contents 30 Ampoule(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 241050
Product type Mineral
Supplement form Liquid
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gammadyn Mn-Co by UNDA Gammadyn, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.07 fl. Oz.
Maximum serving Sizes:
0.07 fl. Oz.
Servings per container
30
UPC/BARCODE
883196313501
IngredientAmount% DV
Manganese0.073 mg3%
Cobalt0.073 mg--

Other ingredients: purified Water, Glucose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Adults: Take 1 ampoule 1 to 2 times daily or as recommended by your health professional. Squeeze contents directly into mouth. Use for 1 to 2 months or as recommended by your healthcare professional.

Precautions

Warning: If you have iodine deficiency, tuberculosis, or a history of tuberculosis, do not use.

If you are pregnant or lactating, if you are taking any medication or Vitamin B12, or have any health condition, particularly liver disease, consult your health professional before use. If gastrointestinal upset or skin rashes occur, stop use and consult your health professional.

Keep out of reach of children.

Do not use if ampoule is broken.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Formula

Manganese-Cobalt

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Seroyal UNDA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gammadyn Mn-Co by UNDA Gammadyn label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gammadyn Mn-Co label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gammadyn Mn-Co by UNDA Gammadyn

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.07 fl. Oz. Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Manganese

Interacts with
83 drugs
0.073 mg per serving Form: Manganese Gluconate

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Cobalt

No known
interactions
0.073 mg per serving Form: Cobalt Gluconate

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements,...

Cobalt monograph & interactions

Other (inactive) ingredients: Purified Water, Glucose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gammadyn Mn-Co by UNDA Gammadyn Drug Interactions

Want to check YOUR meds against Gammadyn Mn-Co?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
83Drugs
83 Moderate

Ingredients driving the most interactions

Manganese 83

Individual Drug Interactions

The ingredients in Gammadyn Mn-Co interact with 83 drugs. Click any drug to see the details.

1 of the 2 ingredients in Gammadyn Mn-Co interact with drugs. Each result below shows which ingredient is responsible. Manganese

Each ingredient & the kinds of drugs it affects

For each ingredient in Gammadyn Mn-Co with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Manganese full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gammadyn Mn-Co, from the product label.

UNDA Gammadyn

See all UNDA Gammadyn products
Name
Seroyal USA
City
Pittsburg
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

Gammadyn Mn-Co by UNDA Gammadyn: Common Questions

Does Gammadyn Mn-Co by UNDA Gammadyn interact with any medications?
Yes. Based on its ingredients, Gammadyn Mn-Co has a known interaction with 83 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gammadyn Mn-Co contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is manganese, and why is it in this supplement?
Manganese is an essential mineral your body uses for bone support, metabolism, and nerve function. It's included here because the product is designed to treat manganese deficiency. You get manganese naturally from foods like nuts, whole grains, and leafy greens.
What about the cobalt — is that a safe form of B12?
Cobalt is part of vitamin B12, but inorganic cobalt supplements (like the form in this product) don't have proven benefits and aren't a reliable B12 source. If you need B12, ask your doctor about B12-specific supplements or injections instead.
Can I take this if I'm pregnant or breastfeeding?
Cobalt should be avoided during pregnancy due to toxicity concerns and lack of safety data. For breastfeeding, the safety data isn't clear — the label advises against cobalt supplements while nursing. Talk with your doctor or pharmacist before taking this product if you're pregnant or nursing.
What are the main side effects of manganese at high doses?
High-dose manganese can cause serious nerve damage, including Parkinson-like symptoms and neurotoxicity. It can also harm the liver, causing cirrhosis and fatty liver disease. These are rare but serious risks, which is why manganese supplements should only be used as directed by your healthcare provider.
Does this product have any fillers or other inactive ingredients?
Yes — it contains purified water and glucose as inactive ingredients to make up the liquid formula. The two active ingredients are manganese and cobalt.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gammadyn Mn-Co label
Go deeper

The Full Monographs Behind Gammadyn Mn-Co’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Manganese

Interacts with 83 drugs

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get enough from a normal diet. Supplements m...

Read the full Manganese monograph → Herb & supplement monograph

Cobalt

Cobalt is a trace element that the body only needs as part of vitamin B12 (cobalamin); there is no proven reason to take inorganic cobalt supplements, and doing so can be harmful. If you nee...

Read the full Cobalt monograph →
Sources

Sources & How We Checked

Gammadyn Mn-Co's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Manganese 21 references
  1. Hansten PD, Horn JR. Hansten and Horn's Drug Interactions Analysis and Management. Vancouver, CAN:Appl Therapeut, 1999.
  2. Barrington WW, Angle CR, Willcockson NK, et al. Autonomic function in manganese alloy workers. Environ Res 1998;78:50-8. PubMed
  3. Hauser RA, Zesiewicz TA, Martinez C, et al. Blood manganese correlates with brain magnetic resonance imaging changes in patients with liver disease. Can J Neurol Sci 1996;23:95-8. PubMed
  4. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  5. Lee JW. Manganese intoxication. Arch Neurol 2000;57:597-9.. PubMed
  6. Powers KM, Smith-Weller T, Franklin GM, et al. Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes. Neurology 2003;60:1761-6.. PubMed
  7. McMillan, D. E. A brief history of the neurobehavioral toxicity of manganese: some unanswered questions. Neurotoxicology 1999;20(2-3):499-507.
  8. Gerber, G. B., Leonard, A., and Hantson, P. Carcinogenicity, mutagenicity and teratogenicity of manganese compounds. Crit Rev Oncol Hematol. 2002;42(1):25-34. PubMed
  9. Jiang, Y. and Zheng, W. Cardiovascular toxicities upon manganese exposure. Cardiovasc.Toxicol 2005;5(4):345-354. PubMed
  10. Mehta, R. and Reilly, J. J. Manganese levels in a jaundiced long-term total parenteral nutrition patient: potentiation of haloperidol toxicity? Case report and literature review. JPEN J Parenter.Enteral Nutr 1990;14(4):428-430. PubMed
  11. Nemery, B. Metal toxicity and the respiratory tract. Eur Respir.J 1990;3(2):202-219. DOI
  12. Vanek VW, Borum P, Buchman A, et al. A.S.P.E.N. position paper: recommendations for changes in commercially available parenteral multivitamin and multi-trace element products. Nutr Clin Pract. 2012;27:440-491.doi: 10.1177/0884533612446706 PubMed
  13. Schuh MJ. Possible Parkinson's disease induced by chronic manganese supplement ingestion. Consult Pharm. 2016;31(12):698-703. doi: 10.4140/TCP.n.2016.698. PubMed
  14. Baker B, Ali A, Isenring L. Recommendations for manganese supplementation to adult patients receiving long-term home parenteral nutrition: an analysis of the supporting evidence. Nutr Clin Pract 2016;31(2):180-5. doi: 10.1177/0884533615591600. PubMed
  15. Ho CSH, Ho RCM, Quek AML. Chronic manganese toxicity associated with voltage-gated potassium channel complex antibodies in a relapsing neuropsychiatric disorder. Int J Environ Res Public Health 2018;15(4). pii: E783. doi: 10.3390/ijerph15040783. PubMed
  16. Yamamoto M, Sakurai K, Eguchi A, et al.; Japan Environment and Children's Study Group: Association between blood manganese level during pregnancy and birth size: the Japan environment and children's study (JECS). Environ Res 2019;172:117-26. PubMed
  17. Li D, Ge X, Liu Z, et al. Association between long-term occupational manganese exposure and bone quality among retired workers. Environ Sci Pollut Res Int 2020;27(1):482-9. PubMed
  18. Martin KV, Sucharew H, Dietrich KN, et al. Co-exposure to manganese and lead and pediatric neurocognition in East Liverpool, Ohio. Environ Res 2021;202:111644. PubMed
  19. Racette BA, Nelson G, Dlamini WW, et al. Depression and anxiety in a manganese-exposed community. Neurotoxicology 2021;85:222-33. PubMed
  20. Ruiz-Azcona L, Fernández-Olmo I, Expósito A, et al. Impact of environmental airborne manganese exposure on cognitive and motor functions in adults: a systematic review and meta-analysis. Int J Environ Res Public Health 2021;18(8):4075. PubMed
  21. Uyar E, Gurkas E, Aksu AU, et al. Can therapeutic plasma exchange be life-saving in life-threatening manganese intoxication?. Transfus Apher Sci 2022;61(4):103417. PubMed

See these in context on the Manganese monograph →

Cobalt 11 references
  1. Packer M. Cobalt cardiomyopathy: a critical reappraisal in light of a recent resurgence. Circ Heart Fail 2016;9(12). pii: e003604. PubMed
  2. Adams TN, Butt YM, Batra K, Glazer CS. Cobalt related interstitial lung disease. Respir Med 2017;129:91-7. PubMed
  3. Lim CA, Khan J, Chelva E, Khan R, Unsworth-Smith T. The effect of cobalt on the human eye. Doc Ophthalmol 2015;130(1):43-8. PubMed
  4. Guarneri F, Guarneri C, Cannavò SP. Nail-art and cobalt allergy. Contact Dermatitis 2010;62(5):320-1. PubMed
  5. Fowler JF Jr. Cobalt. Dermatitis 2016;27(1):3-8.
  6. Zajdel NJ, Smith WA, Taintor AR, Jacob SE, Olasz EB. Chemical tattoo treatment leading to systemic cobalt hypersensitivity. Skinmed 2017;15(3):221-2.
  7. Bregnbak D, Opstrup MS, Jellesen MS, Johansen JD, Thyssen JP. Allergic contact dermatitis caused by cobalt in leather - clinical cases. Contact Dermatitis 2017;76(6):366-8. PubMed
  8. Simonsen AB, Friis UF, Johansen JD, Zachariae C, Sloth JJ, Thyssen JP. Occupational allergic contact dermatitis caused by cobalt in machine oil. Contact Dermatitis 2019;80(1):59-61. PubMed
  9. Paustenbach DJ, Galbraith DA, Finley BL. Interpreting cobalt blood concentrations in hip implant patients. Clin Toxicol (Phila) 2014;52(2):98-112. PubMed
  10. Zywiel MG, Cherian JJ, Banerjee S, et al. Systemic cobalt toxicity from total hip arthroplasties: review of a rare condition Part 2. measurement, risk factors, and step-wise approach to treatment. Bone Joint J 2016;98-B(1):14-20. PubMed
  11. Catalani S, Rizzetti MC, Padovani A, Apostoli P. Neurotoxicity of cobalt. Hum Exp Toxicol 2012;31(5):421-37. PubMed

See these in context on the Cobalt monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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