Hemp Extract 2500 mg Ingredients & Drug Interactions
by Terra Origin
What is this page for?
First and foremost: checking Hemp Extract 2500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Hemp Extract 2500 mg is a dietary supplement by Terra Origin with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp stalk and stem extract Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Hemp Extract 2500 mg by Terra Origin
Ask about any prescription or over-the-counter medication and we check it for interactions with Hemp Extract 2500 mg by Terra Origin — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Hemp Extract 2500 mg by Terra Origin
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Most active ingredients list an amount, but at least one is hidden in a blend or missing.
Why this rating?
- The label discloses an exact amount for 1 of its 2 active ingredients.
- “Proprietary Blend” is a proprietary blend — the label gives one combined amount (475 mg) without saying how much of each component you get.
- “Hemp stalk and stem extract Oil” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryPartially disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Hemp Extract 2500 mg, straight from the product label.
| Brand | Terra Origin |
|---|---|
| Barcode (UPC) | 857668007595 |
| Net contents | 30 Liquid Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 22, 2021 |
| DSLD ID | 247924 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Hemp Extract 2500 mg by Terra Origin, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 475 mg | -- |
| Total Phytocannabinoids | 15 mg | -- |
| Medium Chain Triglycerides oil | 0 NP | -- |
| Hemp stalk and stem extract Oil | 0 NP | -- |
Other ingredients: Hypromellose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
This formula is a unique blend of phytocannabinoids, from mature hemp stalks and stems, with medium chain triglyceride (MCT) oil, derived from coconut oil, to provide a concentrated blend of support for your endocannabinoid system. MCT oil not only improves insulin resistance, increases energy, facilitates cognitive functioning and supports fat loss, it is also the perfect carrier for fat soluble, CBD oil. This blend of phytocannabinoids was designed to balance your nervous system to lower stress and anxiety, decrease inflammation, support pain management and improve sleep. (Non-psychotropic.)
Made in FDA approved facility Made in USA 100% Natural Pain relief Anxiety Anti-inflammatory
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use As a dietary supplement, adults take one (1) CBD capsule one (1) to two (2) times daily, or as directed by a healthcare professional.
Storage
Warnings Store in a cool, dry place.
Precautions
Use only as directed.
This product is not intended for persons under the age of 18.
Consult with your healthcare practitioner prior to consumption if you have any preexisting medical conditions or are on any medication.
Keep out of reach of children.
Do not use if safety seal is broken or missing.
Brand IP Statement(s)
2017 Terra Origin, Inc.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Hemp Extract 2500 mg by Terra Origin label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Hemp Extract 2500 mg by Terra Origin
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Liquid Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Medium Chain Triglycerides oil
- › Hemp stalk and stem extract Oil
Other (inactive) ingredients: Hypromellose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Hemp Extract 2500 mg by Terra Origin Drug Interactions
Hemp Extract 2500 mg contains 2 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 938 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Hemp Extract 2500 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Hemp Extract 2500 mg interact with 938 drugs. Click any drug to see the details.
1 of the 2 ingredients in Hemp Extract 2500 mg interact with drugs. Each result below shows which ingredient is responsible. Hemp stalk and stem extract Oil
Etonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Etonogestrel, Ethinyl Estradiol interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Levonorgestrel, Ethinyl Estradiol interactionMedroxyprogesterone Acetate, Oestrogens, ConjugatedPremique
How Medroxyprogesterone Acetate, Oestrogens, Conjugated interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Stalk And Stem Extract Oil + Medroxyprogesterone Acetate, Oestrogens, Conjugated interactionNorelgestromin, Ethinyl EstradiolEvra, Ortho Evra
How Norelgestromin, Ethinyl Estradiol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Stalk And Stem Extract Oil + Norelgestromin, Ethinyl Estradiol interactionNorethindrone Acetate, Ethinyl Estradiol, Ferrous FumarateLoMinastrin FE, Minastrin 24 FE
How Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interactionOestrogenOestrogen
How Oestrogen interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Oestrogen interactionPrasterone (prescription Drug)Intrarosa
How Prasterone (prescription Drug) interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Stalk And Stem Extract Oil + Prasterone (prescription Drug) interactionRelugolix, Estradiol, Norethindrone AcetateMyfembree
How Relugolix, Estradiol, Norethindrone Acetate interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Relugolix, Estradiol, Norethindrone Acetate interactionSegesterone Acetate, Ethinyl EstradiolAnnovera
How Segesterone Acetate, Ethinyl Estradiol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Stalk And Stem Extract Oil + Segesterone Acetate, Ethinyl Estradiol interactionTiboloneLivial
How Tibolone interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Stalk And Stem Extract Oil + Tibolone interactionDrospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Drospirenone, Ethinyl Estradiol, Levomefolate interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Stalk And Stem Extract Oil + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Stalk And Stem Extract Oil + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acalabrutinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Hemp Stalk And Stem Extract Oil + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Stalk And Stem Extract Oil + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Hemp Extract 2500 mg — through 1 ingredient. Tap an ingredient for the detail:
Hemp Stalk And Stem Extract OilCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Stalk And Stem Extract Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Hemp Extract 2500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp stalk and stem extract Oil
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Hemp Extract 2500 mg, from the product label.
Terra Origin
See all Terra Origin products- Name
- Terra Origin Inc
- Street Address
- 330 Oser Avenue
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- (631)300-2306
- Web Address
- www.TerraOrigin.com
Hemp Extract 2500 mg by Terra Origin: Common Questions
Does Hemp Extract 2500 mg by Terra Origin interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Hemp Extract 2500 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Hemp Extract 2500 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Hemp Extract 2500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC