Ideal CBD 25 mg Ingredients & Drug Interactions
by Barlean's
What is this page for?
First and foremost: checking Ideal CBD 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ideal CBD 25 mg is a dietary supplement by Barlean's with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are full spectrum Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ideal CBD 25 mg by Barlean's
Ask about any prescription or over-the-counter medication and we check it for interactions with Ideal CBD 25 mg by Barlean's — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ideal CBD 25 mg by Barlean's
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Ideal CBD 25 mg has two active ingredients: full spectrum hemp extract and a cannabinoid. The hemp extract is a whole-plant concentrate that contains multiple compounds from the hemp plant, including cannabinoids and other phytochemicals.
The product also contains MCT oil and a softgel capsule as inactive ingredients.
Does it work?
Couldn't assess
The data we hold does not establish that full spectrum hemp extract is effective for constipation, eczema (atopic dermatitis), or high cholesterol (familial hypercholesterolemia) — the evidence is insufficient to rate it for these uses. We have no effectiveness information on file for the cannabinoid ingredient in this product.
How safe is it?
Well-documented data
Hemp seed foods are generally well tolerated in normal amounts, but concentrated extracts and supplements like this one are less studied, so caution is advised. Serious side effects are rare but have been reported: anaphylaxis, allergic reactions (hives, facial swelling, shortness of breath), and in one case report, elevated liver enzymes and hepatitis in a young child taking very high doses.
Common allergies to hemp seed do occur, though uncommonly. We have no pregnancy or lactation safety data on file for either ingredient in this product — talk with your doctor or pharmacist about whether it's appropriate for you.
Meds to double-check
Moderate interaction found
Before taking Ideal CBD 25 mg, check with your doctor or pharmacist if you take estrogen or hormone therapy (Moderate severity), blood thinners like warfarin or aspirin, blood pressure medications (including ACE inhibitors), or any drugs processed by your liver's CYP1A2 or CYP3A4 enzymes — these are common medications for heart rhythm, anxiety, and other conditions. No interactions are documented for the cannabinoid ingredient we could check.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is best approached with caution if you take hormone therapy, blood thinners, blood pressure medications, or drugs your liver processes heavily — all of which may interact with the hemp extract. Because concentrated hemp extracts are less studied than whole foods, and because one ingredient here couldn't be checked for interactions, run your medications through our tool and then discuss the results with your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ideal CBD 25 mg, straight from the product label.
| Brand | Barlean's |
|---|---|
| Barcode (UPC) | 705875801140 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Nov 21, 2020 |
| DSLD ID | 239180 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ideal CBD 25 mg by Barlean's, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Fat | 0.5 Gram(s) | 1% |
| Saturated Fat | 0.5 Gram(s) | 3% |
| full spectrum Hemp extract | 35 mg | -- |
| Cannabinoid | 25 mg | -- |
Other ingredients: MCT Oil, Softgel, Full Spectrum Hemp Extract
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions for use: 1 softgel as needed.
Storage
Keep bottle tightly closed. Store in a cool, dry place.
General Statements
Carpe CBDiem!
ESTD 1989 Barlean's
BPA and Phthalate free bottle
Formulation
Non-GMO Gluten free
Barlean's is U.S. Hemp Authority certified for superior manufacturing processes.
Product of U.S.A.
Precautions
Warning: Consult your physician before use.
Do not use if you are pregnant or nursing.
Keep out of reach of children.
Brand IP Statement(s)
Patents: www.barleans.com/patents
Formula
750 mg CBD 25 mg CBD per serving Less than 0.3% THC
Seals/Symbols
H US Hemp Authority Certified
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ideal CBD 25 mg by Barlean's label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ideal CBD 25 mg by Barlean's
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Full spectrum Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Full spectrum Hemp extract monograph & interactionsCannabinoid
Other (inactive) ingredients: MCT Oil, Softgel, Full Spectrum Hemp Extract. These complete the product’s ingredient list but are not active constituents.
Ideal CBD 25 mg by Barlean's Drug Interactions
HelloPharmacist Interaction Report
Ideal CBD 25 mg by Barlean's contains full spectrum hemp extract, which interacts with several medication types.
The most serious concern is with estrogens (hormone therapies) — hemp may interfere with how your body regulates these hormones, a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Hemp also has Minor interactions with blood thinners (anticoagulants/antiplatelets), blood pressure medications (antihypertensive drugs and ACE inhibitors), and drugs processed by your liver's CYP1A2 and CYP3A4 enzymes. With blood thinners, there's a theoretical bleeding risk; with blood pressure drugs, there's a risk of blood pressure dropping too low; and with liver-processed medications, hemp may reduce how well those drugs work.
The product also contains a cannabinoid ingredient we could not check for interactions — we hold no data for it. Altogether, these interactions span 939 individual medications.
Before you start this product, run your exact medications through the interaction checker on this page, and then confirm the results with your own doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ideal CBD 25 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ideal CBD 25 mg interact with 938 drugs. Click any drug to see the details.
1 of the 2 ingredients in Ideal CBD 25 mg interact with drugs. Each result below shows which ingredient is responsible. full spectrum Hemp extract
Etonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Etonogestrel, Ethinyl Estradiol interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Levonorgestrel, Ethinyl Estradiol interactionMedroxyprogesterone Acetate, Oestrogens, ConjugatedPremique
How Medroxyprogesterone Acetate, Oestrogens, Conjugated interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Medroxyprogesterone Acetate, Oestrogens, Conjugated interactionNorelgestromin, Ethinyl EstradiolEvra, Ortho Evra
How Norelgestromin, Ethinyl Estradiol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Norelgestromin, Ethinyl Estradiol interactionNorethindrone Acetate, Ethinyl Estradiol, Ferrous FumarateLoMinastrin FE, Minastrin 24 FE
How Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interactionOestrogenOestrogen
How Oestrogen interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Oestrogen interactionPrasterone (prescription Drug)Intrarosa
How Prasterone (prescription Drug) interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Prasterone (prescription Drug) interactionRelugolix, Estradiol, Norethindrone AcetateMyfembree
How Relugolix, Estradiol, Norethindrone Acetate interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Relugolix, Estradiol, Norethindrone Acetate interactionSegesterone Acetate, Ethinyl EstradiolAnnovera
How Segesterone Acetate, Ethinyl Estradiol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Segesterone Acetate, Ethinyl Estradiol interactionTiboloneLivial
How Tibolone interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Full Spectrum Hemp Extract + Tibolone interactionDrospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Drospirenone, Ethinyl Estradiol, Levomefolate interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Acalabrutinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Full Spectrum Hemp Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Ideal CBD 25 mg — through 1 ingredient. Tap an ingredient for the detail:
Full Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Full Spectrum Hemp Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ideal CBD 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
full spectrum Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Ideal CBD 25 mg, from the product label.
Barlean's
See all Barlean's products- Name
- Barlean's
- City
- Ferndale
- State
- WA
- ZipCode
- 98248
- Phone Number
- 800-445-3529
- Web Address
- barleans.com
Ideal CBD 25 mg by Barlean's: Common Questions
Does Ideal CBD 25 mg by Barlean's interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on birth control or hormone replacement?
Is hemp extract safe during pregnancy or breastfeeding?
What are the side effects?
Does this actually work for anything?
Why do I need to check my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ideal CBD 25 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ideal CBD 25 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ideal CBD 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC