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Dietary supplement

Manganese Chelate 10 mg Ingredients & Drug Interactions

by NutraBio

Capsule Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Manganese Chelate 10 mg is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for bone health support, antioxidant and enzyme support, filling dietary gaps.Based on those ingredients, 83 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Manganese. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Manganese Chelate 10 mg by NutraBio

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: manganese, at 10 mg per capsule. Manganese is a mineral your body needs for bone health, metabolism, and wound healing.

The capsule also contains rice flour and a vegetable capsule shell as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Manganese's overall clinical evidence instead.

Strong

Strong clinical evidence supports Manganese for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Manganese deficiency — rated "Effective" (Natural Medicines).

Manganese is effective for treating manganese deficiency. For other uses listed on the label—allergic rhinitis (hay fever), osteoporosis, COPD, obesity, and osteoarthritis—the evidence we hold is insufficient to rate whether it works.

If you're considering this supplement for one of those conditions, talk with your doctor about whether it's right for you.

The evidence, ingredient by ingredient Manganese

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Manganese in normal dietary amounts is generally well tolerated. However, high-dose supplements can be harmful—there's concern that higher doses may increase the risk of neurotoxicity, including Parkinson-like symptoms.

One severe case of irreversible Parkinson disease possibly linked to 100 mg daily for 2 to 4 years has been reported, and manganese intoxication can also damage the liver. This 10 mg dose is a standard supplement level, but if you're taking manganese regularly or have liver disease, talk with your doctor about what's safe for you.

For pregnancy and breastfeeding, safety data shows conflicting ratings in our files—talk with your doctor or pharmacist before taking this supplement during either.

Side effects, ingredient by ingredient Manganese

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Manganese.
  • The most serious interaction on file is rated Moderate.
  • For scale: 83 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use antipsychotic drugs (such as haloperidol), quinolone antibiotics (such as ciprofloxacin or levofloxacin), or tetracycline antibiotics (such as doxycycline). These are the medication types documented to interact with manganese.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is useful if you have a manganese deficiency. If you take antipsychotics, quinolone antibiotics, or tetracycline antibiotics, you'll want to check with your doctor or pharmacist before adding it—manganese can interfere with how these drugs work.

High-dose manganese carries a risk of nerve damage and liver problems, so stick with your doctor's or pharmacist's guidance on dose and duration.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Manganese Chelate 10 mg, straight from the product label.

Brand NutraBio
Barcode (UPC) 649908513863
Net contents 120 V-Cap(s)
Market status On market
Date entered into DSLD Feb 26, 2020
DSLD ID 212888
Product type Mineral
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Manganese Chelate 10 mg by NutraBio, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetable Capsule(s)
Maximum serving Sizes:
1 Vegetable Capsule(s)
Servings per container
120
UPC/BARCODE
649908513863
IngredientAmount% DV
Manganese10 mg500%

Other ingredients: Rice Flour, Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily, preferably with meal, or as directed by your physician.

Formulation

Vegetarian

Non-GMO BSE/TSE free

HPLC lab tested for potency

Precautions

Warning: Not intended for use by persons under the age of 18. Keep out of the reach of children.

If you are pregnant, breast feeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.

Discontinue use two weeks prior to surgery.

Brand IP Statement(s)

Albion Minerals and TRAACS are trademarks of Albion Laboratories, Inc.

General Statements

Manufactured in our GMP & FDA inspected facility FDA Registration: 16906175560 Since 1996

Seals/Symbols

Made in USA Made in our GMP & FDA inspected facility OU (Kosher)

Formula

OU (Kosher)

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Manganese Chelate 10 mg by NutraBio label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Manganese Chelate 10 mg by NutraBio

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetable Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Manganese

Interacts with
83 drugs
10 mg per serving Form: TRAACS Manganese Glycinate Chelate

Manganese is an essential trace mineral your body needs in small amounts for bone formation, metabolism, and antioxidant defense, and most people get...

Manganese monograph & interactions

Other (inactive) ingredients: Rice Flour, Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Manganese Chelate 10 mg by NutraBio Drug Interactions

Want to check YOUR meds against Manganese Chelate 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
83Drugs
83 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Manganese Chelate 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Manganese3 drug types · 83 drugs

Antipsychotic Drugs

Theoretically, the risk for manganese toxicity might increase when taken with antipsychotic drugs.
Hallucinations and behavioral changes have been reported in a patient with liver disease who was taking haloperidol and manganese. Researchers speculate that taking manganese along with haloperidol, phenothiazine-derivatives, or other antipsychotic medications might increase the risk of manganese toxicity in some patients.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, manganese might reduce the absorption of quinolone antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced quinolone absorption have been reported between quinolones and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, manganese might reduce the absorption of tetracycline antibiotics.
Manganese is a multivalent cation. Interactions resulting in reduced tetracycline absorption have been reported between tetracyclines and other multivalent cations, such as calcium and iron.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Manganese Chelate 10 mg, from the product label.

NutraBio

See all NutraBio products
Name
NutraBio Labs, Inc.
Street Address
564 Lincoln Blvd.
City
Middlesex
State
NJ
ZipCode
08846
Phone Number
732-748-8606
Web Address
www.nutrabio.com
Pharmacist Counseling Corner

Manganese Chelate 10 mg by NutraBio: Common Questions

Does Manganese Chelate 10 mg by NutraBio interact with any medications?
Yes. Based on its ingredients, Manganese Chelate 10 mg has a known interaction with 83 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Manganese Chelate 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will manganese interact with my antipsychotic medication?
Yes—there's a documented moderate interaction. Manganese may theoretically increase the risk of manganese toxicity when taken with antipsychotics like haloperidol, and cases of hallucinations and behavioral changes have been reported. Check with your doctor or pharmacist before combining them.
Can I take this if I'm on an antibiotic?
It depends on which antibiotic. Manganese can reduce how your body absorbs quinolone antibiotics (like ciprofloxacin) and tetracycline antibiotics (like doxycycline). If you're on either type, talk with your pharmacist—you may need to space them apart or skip the manganese while on antibiotics.
Is manganese safe at this 10 mg dose?
Ten milligrams is a standard supplement dose and is generally well tolerated. However, high-dose manganese over time can cause nerve damage and liver problems. Stick with the dose on the label and let your doctor know if you're taking it long-term, especially if you have any liver concerns.
Will this help my osteoarthritis or hay fever?
The evidence we hold is insufficient to say whether manganese works for those conditions. If you're interested in using it for either, talk with your doctor about whether it's a reasonable choice for you.
Is this safe during pregnancy or breastfeeding?
Our data shows conflicting safety ratings for lactation and no clear guidance for pregnancy. Talk with your doctor or pharmacist before taking this during either—they can give you personalized advice based on your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Manganese Chelate 10 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Manganese Chelate 10 mg label
Go deeper

The Full Monographs Behind Manganese Chelate 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Manganese Chelate 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Manganese 21 references
  1. Hansten PD, Horn JR. Hansten and Horn's Drug Interactions Analysis and Management. Vancouver, CAN:Appl Therapeut, 1999.
  2. Barrington WW, Angle CR, Willcockson NK, et al. Autonomic function in manganese alloy workers. Environ Res 1998;78:50-8. PubMed
  3. Hauser RA, Zesiewicz TA, Martinez C, et al. Blood manganese correlates with brain magnetic resonance imaging changes in patients with liver disease. Can J Neurol Sci 1996;23:95-8. PubMed
  4. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  5. Lee JW. Manganese intoxication. Arch Neurol 2000;57:597-9.. PubMed
  6. Powers KM, Smith-Weller T, Franklin GM, et al. Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes. Neurology 2003;60:1761-6.. PubMed
  7. McMillan, D. E. A brief history of the neurobehavioral toxicity of manganese: some unanswered questions. Neurotoxicology 1999;20(2-3):499-507.
  8. Gerber, G. B., Leonard, A., and Hantson, P. Carcinogenicity, mutagenicity and teratogenicity of manganese compounds. Crit Rev Oncol Hematol. 2002;42(1):25-34. PubMed
  9. Jiang, Y. and Zheng, W. Cardiovascular toxicities upon manganese exposure. Cardiovasc.Toxicol 2005;5(4):345-354. PubMed
  10. Mehta, R. and Reilly, J. J. Manganese levels in a jaundiced long-term total parenteral nutrition patient: potentiation of haloperidol toxicity? Case report and literature review. JPEN J Parenter.Enteral Nutr 1990;14(4):428-430. PubMed
  11. Nemery, B. Metal toxicity and the respiratory tract. Eur Respir.J 1990;3(2):202-219. DOI
  12. Vanek VW, Borum P, Buchman A, et al. A.S.P.E.N. position paper: recommendations for changes in commercially available parenteral multivitamin and multi-trace element products. Nutr Clin Pract. 2012;27:440-491.doi: 10.1177/0884533612446706 PubMed
  13. Schuh MJ. Possible Parkinson's disease induced by chronic manganese supplement ingestion. Consult Pharm. 2016;31(12):698-703. doi: 10.4140/TCP.n.2016.698. PubMed
  14. Baker B, Ali A, Isenring L. Recommendations for manganese supplementation to adult patients receiving long-term home parenteral nutrition: an analysis of the supporting evidence. Nutr Clin Pract 2016;31(2):180-5. doi: 10.1177/0884533615591600. PubMed
  15. Ho CSH, Ho RCM, Quek AML. Chronic manganese toxicity associated with voltage-gated potassium channel complex antibodies in a relapsing neuropsychiatric disorder. Int J Environ Res Public Health 2018;15(4). pii: E783. doi: 10.3390/ijerph15040783. PubMed
  16. Yamamoto M, Sakurai K, Eguchi A, et al.; Japan Environment and Children's Study Group: Association between blood manganese level during pregnancy and birth size: the Japan environment and children's study (JECS). Environ Res 2019;172:117-26. PubMed
  17. Li D, Ge X, Liu Z, et al. Association between long-term occupational manganese exposure and bone quality among retired workers. Environ Sci Pollut Res Int 2020;27(1):482-9. PubMed
  18. Martin KV, Sucharew H, Dietrich KN, et al. Co-exposure to manganese and lead and pediatric neurocognition in East Liverpool, Ohio. Environ Res 2021;202:111644. PubMed
  19. Racette BA, Nelson G, Dlamini WW, et al. Depression and anxiety in a manganese-exposed community. Neurotoxicology 2021;85:222-33. PubMed
  20. Ruiz-Azcona L, Fernández-Olmo I, Expósito A, et al. Impact of environmental airborne manganese exposure on cognitive and motor functions in adults: a systematic review and meta-analysis. Int J Environ Res Public Health 2021;18(8):4075. PubMed
  21. Uyar E, Gurkas E, Aksu AU, et al. Can therapeutic plasma exchange be life-saving in life-threatening manganese intoxication?. Transfus Apher Sci 2022;61(4):103417. PubMed

See these in context on the Manganese monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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