Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Organic Whole Psyllium Husk 5 g Ingredients & Drug Interactions

by Herbal Secrets

Organic Whole Psyllium Husk 5 g label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Whole Psyllium Husk 5 g against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Whole Psyllium Husk 5 g is a dietary supplement by Herbal Secrets with 2 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,025 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, organic whole Psyllium Husk. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Organic Whole Psyllium Husk 5 g by Herbal Secrets

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Whole Psyllium Husk 5 g by Herbal Secrets — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Whole Psyllium Husk 5 g by Herbal Secrets

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains three active ingredients: soluble fiber, insoluble fiber, and organic whole psyllium husk (the main component — blond psyllium). We hold no interaction data for the soluble and insoluble fiber listed separately, so we checked only the psyllium husk itself.

The product also contains psyllium husk as an inactive ingredient (part of the capsule or formulation); that's standard for fiber supplements.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Effective" (Black Psyllium) (Natural Medicines).
  • On file: Hyperlipidemia — rated "Likely Effective" (Blond Psyllium) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Black Psyllium) (Natural Medicines).
  • On file: Diabetes — rated "Possibly Effective" (Blond Psyllium) (Natural Medicines).
  • On file: Diarrhea — rated "Possibly Effective" (Blond Psyllium) (Natural Medicines).

Psyllium husk is effective for constipation and likely effective for high cholesterol (hyperlipidemia) and coronary heart disease prevention. Those are the uses backed by the evidence in our data.

If you're taking it for another reason, the facts we have don't address that.

The evidence, ingredient by ingredient Black Psyllium Blond Psyllium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oral psyllium is generally well tolerated when you drink plenty of water with it. The most common side effects are mild: belly pain, constipation or diarrhea (depending on how your gut reacts), indigestion, gas, and nausea.

Rare but serious risks include bowel or esophageal obstruction — take this with enough liquid and stop if you have severe abdominal pain or trouble swallowing. Some people are allergic to psyllium; allergic reactions range from sneezing and itching to wheezing, swelling, and in rare cases anaphylaxis.

Backache has also been reported. The safety data shows psyllium is likely safe in pregnancy and lactation, though you should still talk with your doctor or midwife before using it while pregnant or breastfeeding.

Side effects, ingredient by ingredient Black Psyllium Blond Psyllium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Blond Psyllium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 2,026 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check your exact medications against metformin, lithium, carbamazepine, olanzapine, and birth control pills — those have documented Moderate or Minor interactions with psyllium. Spacing your psyllium 30–60 minutes after oral medications can help reduce the interaction.

Use the search tool on this page to verify your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Psyllium husk is a well-established fiber supplement for constipation and cholesterol support, and it's generally well tolerated if you drink enough water. If you take metformin, lithium, carbamazepine, olanzapine, or birth control pills, check with your pharmacist before starting — timing matters.

Anyone with a psyllium allergy or swallowing difficulties should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Whole Psyllium Husk 5 g, straight from the product label.

Brand Herbal Secrets
Barcode (UPC) 819209020777
Net contents 24 Ounce(s); 680 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 313285
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Whole Psyllium Husk 5 g by Herbal Secrets, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Gram(s)
Maximum serving Sizes:
5 Gram(s)
Servings per container
136
UPC/BARCODE
819209020777
IngredientAmount% DV
Calories18 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Dietary Fiber4 Gram(s)16%
Fiber, Soluble3 Gram(s)--
Fiber, Insoluble2 Gram(s)--
organic whole Psyllium Husk5 Gram(s)--

Other ingredients: Psyllium Husk

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Nature's best kept secret! At Herbal Secrets, we are committed to bringing you the gift of herbal supplements in their purest form, just as Mother Nature intended.

Visit us online @ amazingnutrition.com

Vitamins Angels Proud Supporter

Precautions

Caution: This product should be consumed with at least a full glass of liquid. Using this product without enough liquid may cause choking. Do not use if you have any difficulty in swallowing. Do not use if safety seal is damaged or missing.

Consult a physician before use if pregnant or nursing, taking medication, planning a medical procedure or have a medical condition.

Keep out of reach of children.

Warning: This product can expose you to chemicals including lead, which are known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Contains no added: Sugar, sodium, cholesterol, fat, or additives.

100% natural

USDA Organic

Non GMO Project Verified nongmoproject.org

Raw An FDA regulated facility

Vegan

Certified Organic by: Natural Food Certifiers

An FDA Regulated Facility

Seals/Symbols

Made in the USA USDA Organic Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Natural Dietary Supplement

Formula

Certified organic fiber Organic Whole Psyllium Husk 5 g per serving

Suggested/Recommended/Usage/Directions

Suggested use: Adults and children over 12 years: One serving per day, best taken before of between meals. Directions: Mix one (1) tablespoon with at least 10 ounces of water, juice or your favorite beverage. Stir and drink immediately. If too thick, add more liquid and stir. Drinking an additional glass of water afterwards is advisable to ensure hydration.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Whole Psyllium Husk 5 g by Herbal Secrets label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Whole Psyllium Husk 5 g label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Whole Psyllium Husk 5 g by Herbal Secrets

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Gram(s) Dosage formPowder Servings per container136 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
4 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions
  • › Fiber, Soluble
  • › Fiber, Insoluble

Organic whole Psyllium Husk

Interacts with
2,025 drugs
5 Gram(s) per serving

Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements. It can help with both...

Organic whole Psyllium Husk monograph & interactions

Other (inactive) ingredients: Psyllium Husk. These complete the product’s ingredient list but are not active constituents.

Interaction report

Organic Whole Psyllium Husk 5 g by Herbal Secrets Drug Interactions

Want to check YOUR meds against Organic Whole Psyllium Husk 5 g?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,025Drugs
23 Moderate 2,002 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
organic whole Psyllium Husk 2,025

Individual Drug Interactions

The ingredients in Organic Whole Psyllium Husk 5 g interact with 2,025 drugs. Click any drug to see the details.

2 of the 2 ingredients in Organic Whole Psyllium Husk 5 g interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber organic whole Psyllium Husk

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Whole Psyllium Husk 5 g with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

organic whole Psyllium Husk7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, blond psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Blond psyllium might reduce carbamazepine absorption and serum levels. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug.

Likelihood Probable Evidence D
Lithium

Theoretically, taking blond psyllium at the same time as lithium might reduce lithium absorption.
The fiber in blond psyllium might decrease the absorption of lithium. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, blond psyllium might increase the therapeutic and adverse effects of metformin.
Concurrent use of blond psyllium with metformin slows and increases metformin absorption. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking blond psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in blond psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was taken concomitantly with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking blond psyllium at the same time as digoxin might reduce digoxin absorption.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking blond psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. However, this is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Conversely, case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin.

Likelihood Possible Evidence B
organic whole Psyllium Husk full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Whole Psyllium Husk 5 g, from the product label.

Herbal Secrets

See all Herbal Secrets products
Name
Herbal Secrets
Street Address
190A Jony Drive
City
Carlstadt
State
NJ
ZipCode
07072
Web Address
amazingnutrition.com
Pharmacist Counseling Corner

Organic Whole Psyllium Husk 5 g by Herbal Secrets: Common Questions

Does Organic Whole Psyllium Husk 5 g by Herbal Secrets interact with any medications?
Yes. Based on its ingredients, Organic Whole Psyllium Husk 5 g has a known interaction with 2,025 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Whole Psyllium Husk 5 g contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my metformin?
Psyllium can increase how much metformin your body absorbs, raising both its effects and side effects. The fix is simple: take your psyllium at least 30–60 minutes after your metformin dose. Talk with your pharmacist to time it right for you.
What are the most common side effects?
Belly pain, gas, diarrhea or constipation, indigestion, and nausea are the most common. They're usually mild and often settle as your gut adjusts. Drink plenty of water — it helps prevent side effects and makes the fiber work better.
Is this safe during pregnancy?
The data shows psyllium is likely safe in pregnancy, but check with your doctor or midwife first. They know your individual situation best.
Can I take this with birth control?
Psyllium may slightly increase how much of the active ingredient in birth control your body absorbs, but this is unlikely to affect how well it works. Still, space them 30–60 minutes apart to be safe, and mention it to your pharmacist.
Does this really work for constipation?
Yes — psyllium is proven effective for constipation. Just make sure you're drinking plenty of water, since it needs liquid to work properly.
Can I be allergic to psyllium?
Some people are. Symptoms range from sneezing and itching to wheezing, facial swelling, and rarely anaphylaxis. If you've never had psyllium before and notice any unusual symptoms, stop and call your doctor right away.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Whole Psyllium Husk 5 g is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Whole Psyllium Husk 5 g label
Go deeper

The Full Monographs Behind Organic Whole Psyllium Husk 5 g’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Blond Psyllium

Interacts with 2,025 drugs

Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements. It can help with both constipation and diarrhea and may modest...

Read the full Blond Psyllium monograph →
Sources

Sources & How We Checked

Organic Whole Psyllium Husk 5 g's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 46 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Blond Psyllium 28 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Agha FP, Nostrant TT, Fiddian-Green RG. Giant colonic bezoar: a medication bezoar due to psyllium seed husks. Am J Gastroenterol 1984;79:319-21.
  7. Anderson JW, Allgood LD, Lawrence A, et al. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. Am J Clin Nutr 2000;71:472-9. PubMed
  8. Suhonen R, Kantola I, Bjorksten F. Anaphylactic shock due to ingestion of psyllium laxative. Allergy 1983;38:363-5. PubMed
  9. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  10. Freeman GL. Psyllium hypersensitivity. Ann Allergy 1994;73:490-2.
  11. Morgan MS, Arlian LG, Vyszenski-Moher DL, et al. English plantain and psyllium: lack of cross-allergenicity by crossed immunoelectrophoresis. Ann Allergy Asthma Immunol 1995;75:351-9.
  12. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  13. Schneider RP. Perdiem causes esophageal impaction and bezoars. South Med J 1989;82:1449-50. PubMed
  14. Shulman LM, Minagar A, Weiner WJ. Perdiem causing esophageal obstruction in Parkinson's disease. Neurology 1999;52:670-1. PubMed
  15. James JM, Cooke SK, Barnett A, Sampson HA. Anaphylactic reactions to a psyllium-containing cereal. J Allergy Clin Immunol 1991;88:402-8.. PubMed
  16. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  17. Schaller DR. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1073. DOI
  18. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  19. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  20. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  21. Bernedo N, García M, Gastaminza G, et al. Allergy to laxative compound (Plantago ovata seed) among health care professionals. J Investig Allergol Clin Immunol 2008;18(3):181-9.
  22. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
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  24. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
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  26. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
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  28. Tominaga Y, Hirayama I, Nonaka M, Yano T, Ishii M. Intestinal obstruction caused by consuming diet food containing psyllium. Acute Med Surg 2023;10(1):e846. PubMed

See these in context on the Blond Psyllium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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