Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango Ingredients & Drug Interactions
by CV Sciences
What is this page for?
First and foremost: checking Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango is a dietary supplement by CV Sciences with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences
Ask about any prescription or over-the-counter medication and we check it for interactions with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Hemp extract” is listed as a grouped ingredient — the label gives one combined amount (20 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango, straight from the product label.
| Brand | CV Sciences |
|---|---|
| Barcode (UPC) | 854521007440 |
| Net contents | 60 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 277003 |
| Product type | Botanical |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| Added Sugars | 2 Gram(s) | 4% |
| Total Sugars | 3 Gram(s) | -- |
| Cannabidiol | 10 mg | -- |
| Hemp extract | 20 mg | -- |
Other ingredients: organic Turbinado Sugar, organic Tapioca Syrup, Water, Purified, Citrus Pectin, Citric Acid, Malic Acid, Natural flavor, Beet
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
10 mg CBD per gummy
Full spectrum hemp extract
Fully decarboxylated & distilled Contains less than 0.3% thc
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
As a dietary supplement, take 1 gummy
General Statements
Discover CV Sciences commitment to quality
Precautions
Not intended for use under the age of 18.
Do not use if pregnant or lactating. If you have a medical condition or are taking medication, consult your doctor before use.
Storage
Store away from direct heat and light.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
No artificial flavoring No artificial sweeteners No gluten No soy Non-GMO
Vegan
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Gummy(ies) Dosage formGummy Or Jelly Servings per container60 Amounts shown are per serving.
Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Hemp extract monograph & interactions- › Cannabidiol
Other (inactive) ingredients: Organic Turbinado Sugar, Organic Tapioca Syrup, Water, Purified, Citrus Pectin, Citric Acid, Malic Acid, Natural flavor, Beet. These complete the product’s ingredient list but are not active constituents.
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences Drug Interactions
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango contains a single active ingredient, and it has known interactions with 938 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango interact with drugs. Each result below shows which ingredient is responsible. Hemp extract
Etonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Etonogestrel, Ethinyl Estradiol interactionLevonorgestrel, Ethinyl EstradiolLogynon ED, Microgynon 30, Nordette, Ovranette, Quartette, Trinordiol +1 more
How Levonorgestrel, Ethinyl Estradiol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Levonorgestrel, Ethinyl Estradiol interactionMedroxyprogesterone Acetate, Oestrogens, ConjugatedPremique
How Medroxyprogesterone Acetate, Oestrogens, Conjugated interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Medroxyprogesterone Acetate, Oestrogens, Conjugated interactionNorelgestromin, Ethinyl EstradiolEvra, Ortho Evra
How Norelgestromin, Ethinyl Estradiol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Norelgestromin, Ethinyl Estradiol interactionNorethindrone Acetate, Ethinyl Estradiol, Ferrous FumarateLoMinastrin FE, Minastrin 24 FE
How Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Norethindrone Acetate, Ethinyl Estradiol, Ferrous Fumarate interactionOestrogenOestrogen
How Oestrogen interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Oestrogen interactionPrasterone (prescription Drug)Intrarosa
How Prasterone (prescription Drug) interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Prasterone (prescription Drug) interactionRelugolix, Estradiol, Norethindrone AcetateMyfembree
How Relugolix, Estradiol, Norethindrone Acetate interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Relugolix, Estradiol, Norethindrone Acetate interactionSegesterone Acetate, Ethinyl EstradiolAnnovera
How Segesterone Acetate, Ethinyl Estradiol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Segesterone Acetate, Ethinyl Estradiol interactionTiboloneLivial
How Tibolone interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractEstrogens Moderate
Interaction Summary
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
Read the full Hemp Extract + Tibolone interactionDrospirenone, Ethinyl Estradiol, LevomefolateBeyaz
How Drospirenone, Ethinyl Estradiol, Levomefolate interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Estrogens +1 Moderate
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Drospirenone, Ethinyl Estradiol, Levomefolate interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acalabrutinib interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Hemp Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Hemp Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango — through 1 ingredient. Tap an ingredient for the detail:
Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Hemp Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango, from the product label.
CV Sciences
See all CV Sciences products- Name
- CV Sciences, Inc.
- Street Address
- 10070 Barnes Canyon Rd
- City
- San Diego
- State
- CA
- ZipCode
- 92121
- Phone Number
- 855-758-7223
- Web Address
- PlusCBDoil.com
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences: Common Questions
Does Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango by CV Sciences interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Plus CBD Extra Strength Formula 10 mg Gummy Cherry Mango's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC