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Dietary supplement

Prickly Ash Ingredients & Drug Interactions

by Herb Pharm

Prickly Ash label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prickly Ash against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Prickly Ash is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for toothache and mouth pain, joint pain and rheumatism, digestive upset.Based on those ingredients, 36 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Prickly Ash bark (Zanthoxylum clava-herculis) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Prickly Ash by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Prickly Ash by Herb Pharm — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Prickly Ash by Herb Pharm

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Northern Prickly Ash.
  • The most serious interaction on file is rated Minor.
  • For scale: 36 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and some safety-information gaps remain.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prickly Ash, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700001995
Net contents 4 fl. Oz.; 120 mL
Market status On market
Date entered into DSLD Jun 24, 2019
DSLD ID 204342
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prickly Ash by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
0.7 mL
Servings per container
168
UPC/BARCODE
090700001995
IngredientAmount% DV
Prickly Ash bark (Zanthoxylum clava-herculis) extract617 mg--

Other ingredients: certified organic Cane Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Shake well before using Add 1 full squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.

Precautions

Caution: Seek expert medical advice before taking during pregnancy.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Zanthoxylum clava-herculis

Prickly Ash liquid extract

We prepare our Prickly Ash extract from the bark of Zanthoxylum clava-herculis trees which are responsibly wildcrafted in their natural wild habitat.

General Statements

Optimal well-being

Dry herb/menstruum ratio: 1:4

FDA Statement of Identity

Herbal Supplement

Formulation

Gluten-free

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prickly Ash by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prickly Ash label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prickly Ash by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.

Prickly Ash bark (Zanthoxylum clava-herculis) extract

Interacts with
36 drugs
617 mg per serving

Northern Prickly Ash is a North American shrub whose bark and berries have a long history in folk medicine, especially for toothache, joint pain, and...

Prickly Ash bark (Zanthoxylum clava-herculis) extract monograph & interactions

Other (inactive) ingredients: Certified organic Cane Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prickly Ash by Herb Pharm Drug Interactions

Prickly Ash contains a single active ingredient, and it has known interactions with 36 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Prickly Ash?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
36Drugs
36 Minor

Ingredients driving the most interactions

Prickly Ash bark (Zanthoxylum clava-herculis) extract 36

Individual Drug Interactions

The ingredients in Prickly Ash interact with 36 drugs. Click any drug to see the details.

1 of the 1 ingredient in Prickly Ash interact with drugs. Each result below shows which ingredient is responsible. Prickly Ash bark (Zanthoxylum clava-herculis) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Prickly Ash with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Prickly Ash bark (Zanthoxylum clava-herculis) extract3 drug types · 36 drugs

Antacids

Theoretically, northern prickly ash might decrease the effectiveness of antacids.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, northern prickly ash might decrease the effectiveness of H2-blockers.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, northern prickly ash might decrease the effectiveness of PPIs.
There are reports that northern prickly ash increases stomach acid.

Likelihood Possible Evidence D
Prickly Ash bark (Zanthoxylum clava-herculis) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prickly Ash, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Prickly Ash by Herb Pharm: Common Questions

Does Prickly Ash by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Prickly Ash has a known interaction with 36 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prickly Ash contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prickly Ash is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prickly Ash label
Go deeper

The Full Monographs Behind Prickly Ash’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Northern Prickly Ash

Interacts with 36 drugs

Northern Prickly Ash is a North American shrub whose bark and berries have a long history in folk medicine, especially for toothache, joint pain, and sluggish digestion. Modern scientific ev...

Read the full Northern Prickly Ash monograph →
Sources

Sources & How We Checked

Prickly Ash's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Northern Prickly Ash 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Northern Prickly Ash monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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