Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

ProstateMD Ingredients & Drug Interactions

by 1MD

ProstateMD label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ProstateMD against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ProstateMD is a dietary supplement by 1MD with 11 active ingredients. Its ingredients are commonly taken for heart health, prostate health, antioxidant support.Based on those ingredients, 456 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pine bark extract, Safflower Oil, USPlus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against ProstateMD by 1MD

Ask about any prescription or over-the-counter medication and we check it for interactions with ProstateMD by 1MD — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of ProstateMD by 1MD

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

ProstateMD contains 11 active ingredients chosen for men's prostate health. Lycopene, a carotenoid from tomatoes, is possibly effective for prostate cancer.

Pine bark extract, pumpkin seed oil, pygeum (an African tree bark), and saw palmetto (USPlus) are all targeted at prostate and urinary symptoms—pygeum is likely effective for benign prostate enlargement, and pumpkin seed oil is possibly effective for the same condition. Stinging nettle is possibly effective for diabetes and may help with prostate-related urinary complaints.

Safflower oil, boron, copper, sunflower lecithin, and lutein round out the formula, though evidence for most of these in prostate health is limited or absent in our data. The product also contains inactive ingredients—bovine gelatin (the capsule), glycerine, sunflower oil, corn oil, and beeswax—which serve as fillers and flow agents but do not add active benefit.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Prostate health and urinary function support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS), Urinary flow, Lower urinary tract symptoms.
  • The strongest evidence on file: Pygeum is rated "Likely Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH).
  • Also on file: Saw Palmetto is rated "Possibly Ineffective" for Benign prostatic hyperplasia (BPH).

Effectiveness data in our records is sparse for most of these ingredients in prostate health specifically. Pygeum is likely effective for benign prostate enlargement (BPH).

Pumpkin seed oil is possibly effective for BPH. Pine bark extract is possibly effective for chronic venous insufficiency and asthma, not directly for prostate concerns.

Lycopene is possibly effective for prostate cancer prevention. For stinging nettle, diabetes, and most of the other ingredients, the evidence we hold is insufficient or shows no clear benefit in prostate conditions.

If you're considering this product for a particular prostate or urinary symptom, talk it over with your doctor to see whether the evidence supports it for your specific situation.

The evidence, ingredient by ingredient Lycopene Lecithin Safflower Maritime Pine Boron Stinging Nettle Lutein Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 11 of the 11 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 11 of 11.
  • General safety write-ups exist for 11 of 11.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in ProstateMD are generally well tolerated at typical doses. Lycopene, lecithin, pumpkin seed oil, lutein, and boron (in normal amounts) are well tolerated; boron becomes toxic at high doses.

Common mild side effects from any of these may include stomach upset, diarrhea, nausea, or abdominal discomfort. Pine bark extract may cause dizziness or vertigo in some people.

Saw palmetto is generally well tolerated, though mild reversible side effects like headache, diarrhea, or fatigue have been reported. Pregnancy and breastfeeding require caution: lycopene supplements should be avoided in pregnancy unless your doctor advises otherwise, and safflower in medicinal amounts should be avoided (it may stimulate the uterus).

Pine bark extract, stinging nettle, pumpkin seed oil concentrated supplements, saw palmetto, and boron supplements should all be avoided in pregnancy and breastfeeding due to lack of safety data or possible harm. Copper and lecithin supplements warrant discussion with your doctor before use in pregnancy or while breastfeeding.

If you are pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Lycopene Lecithin Safflower Maritime Pine Boron Stinging Nettle Lutein Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 11 matched ingredients can interact with medications — Safflower, Lycopene, Stinging Nettle, Pumpkin, Copper, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 456 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking ProstateMD, check with your doctor or pharmacist if you take any blood thinners (anticoagulants) or antiplatelet drugs—lycopene, safflower oil, pine bark extract, and saw palmetto all carry a Moderate bleeding risk with these. Also double-check if you take diabetes medications (safflower oil, pine bark extract, and stinging nettle may lower blood sugar further), lithium (pumpkin seed oil and stinging nettle may raise its levels), diuretics or water pills (stinging nettle may add to their effect), estrogens or birth control (saw palmetto and copper may interfere), or penicillamine (copper may reduce its absorption).

If you take any of these, do not start ProstateMD without clearing it with your own healthcare provider.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

ProstateMD is a multi-ingredient formula aimed at men's prostate health, with some evidence (pygeum, pumpkin seed oil) and some ingredients used traditionally but not well studied. If you take blood thinners, diabetes medications, lithium, diuretics, birth control, or hormone therapy, you must check your exact medications with your doctor or pharmacist before starting—several ingredients here can interact with them.

If you are pregnant, breastfeeding, or have a medical condition, talk with your doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 11 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ProstateMD, straight from the product label.

Brand 1MD
Barcode (UPC) 850008021190
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 246774
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ProstateMD by 1MD, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
850008021190
IngredientAmount% DV
Lycopene15 mg--
Sunflower Lecithin45 mg--
Safflower Oil24 mg--
Pine bark extract45 mg--
Boron2 mg--
Stinging Nettle45 mg--
Lutein6 mg--
Pumpkin seed Oil160 mg--
Pygeum100 mg--
USPlus320 mg--
Copper2 mg222%

Other ingredients: Bovine Gelatin, Glycerine, Sunflower Oil, Corn Oil, Beeswax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take one (1) softgel daily, with a glass of water, or as recommended by a healthcare professional.

Formulation

Preservative-free Gluten-free Dairy-free Non-GMO Soy-free Sugar-free Shellfish-free

Comprehensive prostate support Promotes prostate health Improves urinary tract function Normalizes prostate cell growth

Precautions

Warning: Consult your physician before using this or any product f you are pregnant, nursing, trying to conceive, taking anticoagulants, immunosuppressants, antidiabetics, antihypertensives, or other medications, have coagulopathy, or any medical condition.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

Seals/Symbols

Made in USA GMP Good Manufacturing Practice

General Statements

Doctor recommended

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

USPlus is a registered trademark of U.S. Nutraceuticals, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ProstateMD by 1MD label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ProstateMD label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ProstateMD by 1MD

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lycopene

Interacts with
122 drugs
15 mg per serving

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible hear...

Lycopene monograph & interactions

Sunflower Lecithin

No known
interactions
45 mg per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Sunflower Lecithin monograph & interactions

Safflower Oil

Interacts with
208 drugs
24 mg per serving

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source o...

Safflower Oil monograph & interactions

Pine bark extract

Interacts with
327 drugs
45 mg per serving

Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research...

Pine bark extract monograph & interactions

Boron

No known
interactions
2 mg per serving Form: Boron AAC

Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence f...

Boron monograph & interactions

Stinging Nettle

Interacts with
164 drugs
45 mg per serving

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence...

Stinging Nettle monograph & interactions

Lutein

No known
interactions
6 mg per serving

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Pumpkin seed Oil

Interacts with
1 drug
160 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin seed Oil monograph & interactions

Pygeum

No known
interactions
100 mg per serving

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some st...

Pygeum monograph & interactions

USPlus

Interacts with
174 drugs
320 mg per serving

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no bett...

USPlus monograph & interactions

Copper

Interacts with
31 drugs
2 mg per serving Form: Copper AAC, Copper Chlorophyllin

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Other (inactive) ingredients: Bovine Gelatin, Glycerine, Sunflower Oil, Corn Oil, Beeswax. These complete the product’s ingredient list but are not active constituents.

Interaction report

ProstateMD by 1MD Drug Interactions

Want to check YOUR meds against ProstateMD?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
456Drugs
456 Moderate

Ingredients driving the most interactions

Pine bark extract 327
Safflower Oil 208
USPlus 174
Stinging Nettle 164
Lycopene 122

Individual Drug Interactions

The ingredients in ProstateMD interact with 456 drugs. Click any drug to see the details.

7 of the 11 ingredients in ProstateMD interact with drugs. Each result below shows which ingredient is responsible. Pine bark extract Safflower Oil USPlus Stinging Nettle Lycopene Copper Pumpkin seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in ProstateMD with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Pine bark extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Pine bark extract full monograph & interactions

Safflower Oil3 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence B
Warfarin

Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence D
Safflower Oil full monograph & interactions

USPlus3 drug types · 174 drugs

Anticoagulant/Antiplatelet Drugs

Saw palmetto might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Saw palmetto is reported to prolong bleeding time. Theoretically, it might increase the risk of bleeding when used concomitantly with anticoagulant or antiplatelet drugs.

Likelihood Possible Evidence D
Contraceptive Drugs

Saw palmetto might reduce the effectiveness of contraceptive drugs.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with contraceptive drugs taken concomitantly.

Likelihood Possible Evidence B
Estrogens

Saw palmetto might reduce the effectiveness of estrogens.
Saw palmetto might have antiestrogenic effects. Theoretically, it might interfere with estrogens taken concomitantly.

Likelihood Possible Evidence B
USPlus full monograph & interactions

Stinging Nettle4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle full monograph & interactions

Lycopene1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking lycopene with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lycopene has antiplatelet effects.

Likelihood Possible Evidence D
Lycopene full monograph & interactions

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions

Pumpkin seed Oil1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ProstateMD, from the product label.

1MD

See all 1MD products
Name
1MD
City
Irvine
State
CA
ZipCode
92618
Phone Number
888-393-4030
Web Address
www.1md.org
Pharmacist Counseling Corner

ProstateMD by 1MD: Common Questions

Does ProstateMD by 1MD interact with any medications?
Yes. Based on its ingredients, ProstateMD has a known interaction with 456 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ProstateMD contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is ProstateMD safe to take while pregnant or breastfeeding?
Several ingredients should be avoided in pregnancy and breastfeeding: pine bark extract, stinging nettle, pumpkin seed oil concentrated supplements, saw palmetto, and boron supplements all lack sufficient safety data or carry cautions. Lycopene and safflower oil in medicinal amounts are also not advised. If you are pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist about whether this product is right for you—they can weigh the risks and benefits for your situation.
What is pygeum and why is it in this formula?
Pygeum is a bark extract from an African tree. It is likely effective for benign prostate enlargement, which is why it's included in a prostate health product. It is generally well tolerated, though long-term safety data are limited.
Can I take this if I'm on warfarin (Coumadin)?
No—not without checking with your doctor first. Lycopene, safflower oil, pine bark extract, and saw palmetto all carry a Moderate interaction with warfarin and may increase bleeding risk. One case report even described a patient on warfarin who developed bleeding after taking safflower extract. Your doctor or pharmacist needs to review this product against your warfarin dose before you start.
What side effects might I experience?
Common mild side effects from these ingredients include stomach upset, diarrhea, nausea, or abdominal discomfort. Pine bark extract may cause dizziness or vertigo. Saw palmetto side effects are usually mild and reversible—headache, fatigue, or constipation can occur but are uncommon. If you experience severe or persistent side effects, stop the product and contact your doctor.
Does this product actually work for prostate health?
Some ingredients have evidence: pygeum is likely effective for benign prostate enlargement, and pumpkin seed oil is possibly effective for the same condition. Lycopene is possibly effective for prostate cancer prevention. For the other ingredients, the evidence in our data is insufficient or absent for prostate-specific benefits. Talk with your doctor about whether the ingredients in this formula match your specific prostate concern.
Is there any copper in this product, and should I worry about it?
Yes, copper is one of the 11 active ingredients. Copper is safe in typical supplement amounts, but if you take birth control pills, copper levels may rise slightly—this is usually not a concern, but your doctor can advise. If you take penicillamine (an older medication), you should separate doses of this product and the drug by at least 2 hours to avoid reducing penicillamine absorption.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ProstateMD is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ProstateMD label
Go deeper

The Full Monographs Behind ProstateMD’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lycopene

Interacts with 122 drugs

Lycopene is a red plant pigment and antioxidant found mainly in tomatoes and other red fruits. Eating lycopene-rich foods is linked with possible heart and prostate benefits, but evidence fr...

Read the full Lycopene monograph → Herb & supplement monograph

Lecithin

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...

Read the full Lecithin monograph → Herb & supplement monograph

Safflower

Interacts with 208 drugs

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...

Read the full Safflower monograph → Herb & supplement monograph

Maritime Pine

Interacts with 327 drugs

Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research is promising, but many studies are small...

Read the full Maritime Pine monograph → Herb & supplement monograph

Boron

Boron is a trace mineral found in many plant foods and sold as a supplement, mainly promoted for bone, joint, and hormone health. The human evidence for most of these uses is limited or prel...

Read the full Boron monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Pygeum

Pygeum is an extract from the bark of the African cherry tree that is most often used to ease urinary symptoms linked to an enlarged prostate. Some studies suggest modest benefit for these s...

Read the full Pygeum monograph → Herb & supplement monograph

Saw Palmetto

Interacts with 174 drugs

Saw palmetto is a plant extract most often used for urinary symptoms linked to an enlarged prostate (BPH). The best research suggests it works no better than a placebo for most men, though i...

Read the full Saw Palmetto monograph → Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

ProstateMD's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 119 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lycopene 10 references
  1. Sharma, J. B., Kumar, A., Kumar, A., Malhotra, M., Arora, R., Prasad, S., and Batra, S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gynaecol.Obstet. 2003;81(3):257-262. PubMed
  2. Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S., and Sheu, J. R. Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation. J Lab Clin Med 2005;146(4):216-226. PubMed
  3. Clark, P. E., Hall, M. C., Borden, L. S., Jr., Miller, A. A., Hu, J. J., Lee, W. R., Stindt, D., D'Agostino, R., Jr., Lovato, J., Harmon, M., and Torti, F. M. Phase I-II prospective dose-escalating trial of lycopene in patients with biochemical relapse o
  4. O'Kennedy, N., Crosbie, L., Whelan, S., Luther, V., Horgan, G., Broom, J. I., Webb, D. J., and Duttaroy, A. K. Effects of tomato extract on platelet function: a double-blinded crossover study in healthy humans. Am.J.Clin.Nutr. 2006;84(3):561-569. PubMed
  5. Jatoi, A., Burch, P., Hillman, D., Vanyo, J. M., Dakhil, S., Nikcevich, D., Rowland, K., Morton, R., Flynn, P. J., Young, C., and Tan, W. A tomato-based, lycopene-containing intervention for androgen-independent prostate cancer: results of a Phase II stu
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Lecithin 9 references
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Safflower 14 references
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Maritime Pine 14 references
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Boron 6 references
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Stinging Nettle 23 references
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Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
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Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
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Pygeum 3 references
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Saw Palmetto 22 references
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  2. Carraro JC, Raynaud JP, Koch G, et al. Comparison of phytotherapy (Permixon) with finasteride in the treatment of benign prostate hyperplasia: a randomized international study of 1,098 patients. Prostate 1996;29:231-40. DOI
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Copper 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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