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Dietary supplement

Raspberry Ketones & African Mango Complex Ingredients & Drug Interactions

by Vitamin World

Raspberry Ketones & African Mango Complex label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Raspberry Ketones & African Mango Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Raspberry Ketones & African Mango Complex is a dietary supplement by Vitamin World with 2 active ingredients. Its ingredients are commonly taken for weight loss, fat burning, boosting metabolism.Based on those ingredients, 268 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Raspberry Ketones, African Mango. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Raspberry Ketones & African Mango Complex by Vitamin World

Ask about any prescription or over-the-counter medication and we check it for interactions with Raspberry Ketones & African Mango Complex by Vitamin World — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Raspberry Ketones & African Mango Complex by Vitamin World

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: raspberry ketones and African mango extract (from Irvingia gabonensis). The supplement is delivered in a gelatin capsule with vegetable cellulose and minor other inactive ingredients that serve as binders and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: weight loss and metabolism support.
  • We looked for evidence on: Obesity, Metabolic syndrome, Diabetes, Hypercholesterolemia, appetite control, fat burning.
  • The closest evidence on file: Irvingia Gabonensis is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Irvingia Gabonensis is rated "Insufficient Reliable Evidence To Rate" for Hypercholesterolemia, Obesity, Metabolic syndrome.
  • Also on file: Raspberry Ketone is rated "Insufficient Reliable Evidence To Rate" for Obesity.

The evidence base for both ingredients is limited. For raspberry ketones, we hold ratings of insufficient reliable evidence for alopecia areata (hair loss in patches) and obesity.

African mango similarly carries insufficient reliable evidence ratings for diabetes, high cholesterol, obesity, and metabolic syndrome. Neither ingredient has established effectiveness in our data for any of these uses.

The evidence, ingredient by ingredient Raspberry Ketone Irvingia Gabonensis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Raspberry ketone is used in foods safely, but human safety data for high supplement doses is very limited. In rare cases, oral use has been associated with stimulant-related side effects including heart palpitations, elevated blood pressure, sweating, shakiness, and diarrhea — and one case report documented a serious heart rhythm problem that required treatment.

African mango is generally well tolerated in short-term studies, though long-term safety is not well established. Common side effects include flatulence, headache, insomnia, and nausea; one rare case of liver inflammation was reported.

For pregnancy, safety data is insufficient for both ingredients — the facts advise against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Raspberry Ketone Irvingia Gabonensis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Irvingia Gabonensis, Raspberry Ketone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 268 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take stimulant drugs (such as decongestants or ADHD medications) — raspberry ketone may increase cardiovascular risks. Also confirm it's safe if you take warfarin or other blood thinners, antidiabetes medications, or testosterone products; all carry documented interactions with ingredients in this complex.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is aimed at weight and metabolic support, but the evidence for either ingredient is not established in our data. More importantly, it interacts with several common medication categories — stimulants, blood thinners, diabetes drugs, and testosterone — so you'll need to confirm it's safe with your own doctor or pharmacist before starting, especially if you take any prescription medications.

The safety profile in long-term use is not well characterized.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Raspberry Ketones & African Mango Complex, straight from the product label.

Brand Vitamin World
Barcode (UPC) 766443516569
Net contents 60 Rapid Release Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20487
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Raspberry Ketones & African Mango Complex by Vitamin World, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
766443516569
IngredientAmount% DV
Raspberry Ketones100 mg--
African Mango125 mg--

Other ingredients: Gelatin, Vegetable Cellulose, Contains <2% of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

DIRECTIONS: For adults, take one (1) capsule two times daily, preferably with meals.

General Statements

For over 40 years, Vitamin World has pioneered the manufacture of premium nutritional supplements. Our commitment to quality is the highest in our industry. Every product undergoes rigorous analysis for purity, potency, safety and freshness. We guarantee it!

Concentrated Synergistic Formula

Seals/Symbols

QA QUALITY ASSURED

Formulation

No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Soy, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.

Precautions

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

General

PROD. #51656 B51656 00A

Brand IP Statement(s)

Get healthy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Raspberry Ketones & African Mango Complex by Vitamin World label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Raspberry Ketones & African Mango Complex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Raspberry Ketones & African Mango Complex by Vitamin World

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Raspberry Ketones

Interacts with
174 drugs
100 mg per serving

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence th...

Raspberry Ketones monograph & interactions

African Mango

Interacts with
94 drugs
125 mg per serving

Irvingia gabonensis (African mango) is a seed extract marketed mainly for weight loss and metabolic health. A few small studies suggest possible benef...

African Mango monograph & interactions

Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Contains <2% of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Raspberry Ketones & African Mango Complex by Vitamin World Drug Interactions

Want to check YOUR meds against Raspberry Ketones & African Mango Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
268Drugs
268 Moderate

Ingredients driving the most interactions

Raspberry Ketones 174
African Mango 94

Individual Drug Interactions

The ingredients in Raspberry Ketones & African Mango Complex interact with 268 drugs. Click any drug to see the details.

2 of the 2 ingredients in Raspberry Ketones & African Mango Complex interact with drugs. Each result below shows which ingredient is responsible. Raspberry Ketones African Mango

Each ingredient & the kinds of drugs it affects

For each ingredient in Raspberry Ketones & African Mango Complex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Raspberry Ketones2 drug types · 174 drugs

Stimulant Drugs

Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.

Likelihood Possible Evidence D
Raspberry Ketones full monograph & interactions

African Mango2 drug types · 94 drugs

Antidiabetes Drugs

Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Human research shows that Irvingia gabonensis decreases blood sugar in diabetic patients being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence B
Testosterone

Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Animal research suggests that Irvingia gabonensis increases testosterone levels. The mechanism of action is unclear. Until more is known, advise patients taking testosterone to avoid using or use Irvingia gabonensis cautiously.

Likelihood Possible Evidence D
African Mango full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Raspberry Ketones & African Mango Complex, from the product label.

Vitamin World

See all Vitamin World products
Name
Vitamin World, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Pharmacist Counseling Corner

Raspberry Ketones & African Mango Complex by Vitamin World: Common Questions

Does Raspberry Ketones & African Mango Complex by Vitamin World interact with any medications?
Yes. Based on its ingredients, Raspberry Ketones & African Mango Complex has a known interaction with 268 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Raspberry Ketones & African Mango Complex contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What's the difference between the two ingredients — do they work together?
Raspberry ketone and African mango (Irvingia gabonensis) are two separate active ingredients in this blend. The product combines them, but we hold no evidence that either one is effective for obesity or metabolic issues on its own, so there's no established data on how they'd work together.
Can I take this if I'm trying to get pregnant or am breastfeeding?
The safety data for both ingredients during pregnancy and breastfeeding is not adequate, and the facts advise against use in both situations. Talk with your doctor or pharmacist about whether this product is right for you during this time.
What side effects should I watch for?
Raspberry ketone can cause stimulant-related effects like heart palpitations, elevated blood pressure, sweating, and shakiness — though these are rare. African mango more commonly causes flatulence, headache, insomnia, and nausea. One rare case of liver inflammation from African mango has been reported.
Is this supplement safe long-term?
No — long-term safety data for either ingredient is not well established. Raspberry ketone has very limited human safety data at high supplement doses, and African mango's safety beyond short-term studies is unknown.
Does this product actually work for weight loss?
The evidence isn't established in our data. Both ingredients carry 'insufficient reliable evidence' ratings for obesity, meaning we don't have adequate proof they're effective.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Raspberry Ketones & African Mango Complex label
Go deeper

The Full Monographs Behind Raspberry Ketones & African Mango Complex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Raspberry Ketone

Interacts with 174 drugs

Raspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...

Read the full Raspberry Ketone monograph → Herb & supplement monograph

Irvingia Gabonensis

Interacts with 94 drugs

Irvingia gabonensis (African mango) is a seed extract marketed mainly for weight loss and metabolic health. A few small studies suggest possible benefits, but the research is limited and low...

Read the full Irvingia Gabonensis monograph →
Sources

Sources & How We Checked

Raspberry Ketones & African Mango Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Raspberry Ketone 4 references
  1. Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
  2. Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
  3. Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
  4. Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.

See these in context on the Raspberry Ketone monograph →

Irvingia Gabonensis 7 references
  1. Oben JE, Ngondi JL, Momo CN, et al. The use of Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis 2008;7:12.
  2. Ngondi JL, Etoundi BC, Nyangono CB, et al. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controll
  3. Adamson, I., Okafor, C., and Abu-Bakare, A. A supplement of Dikanut (Irvingia gabonesis) improves treatment of type II diabetics. West Afr.J.Med. 1990;9(2):108-115.
  4. Adamson, I., Okafor, C., and Abu-Bakare, A. Erythrocyte membrane ATPases in diabetes: effect of dikanut (Irvingia gabonensis). Enzyme 1986;36(3):212-215. PubMed
  5. Wolfe OA, Ijeoma UF. Effects of aqueous extracts of Irvingia gabonensis seeds on the hormonal parameters of male guinea pigs. Asian Pacific Journal of Tropical Medicine. 2010;3(3):200-204. DOI
  6. Kilinçalp S, Basar O, Coban S, Yüksel I. Irvingia gabonensis (African mango): innocent magic formula? Acta Gastroenterol Belg 2014;77(1):75-6.
  7. Nonsa-Ard R, Aneknan P, Tong-Un T, Honsawek S, Leelayuwat N. Effects of Irvingia gabonensis Extract on Metabolism, Antioxidants, Adipocytokines, Telomere Length, and Aerobic Capacity in Overweight/Obese Individuals. Nutrients 2022;14(21):4646. PubMed

See these in context on the Irvingia Gabonensis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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