Relief + Relax CBD Softgels 30 mg Ingredients & Drug Interactions
by CBDistillery
What is this page for?
First and foremost: checking Relief + Relax CBD Softgels 30 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Relief + Relax CBD Softgels 30 mg is a dietary supplement by CBDistillery with 1 active ingredient. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 938 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broad Spectrum Hemp extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Relief + Relax CBD Softgels 30 mg by CBDistillery
Ask about any prescription or over-the-counter medication and we check it for interactions with Relief + Relax CBD Softgels 30 mg by CBDistillery — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Relief + Relax CBD Softgels 30 mg by CBDistillery
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Broad Spectrum Hemp extract” is listed as a grouped ingredient — the label gives one combined amount (38 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Relief + Relax CBD Softgels 30 mg, straight from the product label.
| Brand | CBDistillery |
|---|---|
| Barcode (UPC) | 811409033892 |
| Net contents | 30 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 21, 2023 |
| DSLD ID | 286719 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Relief + Relax CBD Softgels 30 mg by CBDistillery, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cannabidiol | 30 mg | -- |
| Broad Spectrum Hemp extract | 38 mg | -- |
Other ingredients: fractionated Coconut Oil, Gelatin, Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
0% THC
Extra strength
Pain from physical activity Mood Inflammation from physical activity Motor control Nausea Memory Appetite Pleasure Immune function
How can CBD help you? With daily CBD use, these are some of the most commonly reported benefits after 7-14 days: Less discomfort More relaxed
Non-addictive Non-intoxicating Naturally farmed
Third party tested to ensure non-detectable levels of THC (less than 0.05%)
Formula
Broad spectrum hemp extract
It contains a total Delta-9-Tetrahydrocannabinol concentration that does not exceed 0.3% on a dry-weight basis, and natural CBD from hemp grown in the U.S.A.
30 mg CBD per serving
The Endocannabinoid System (ECS) CBD binds with cannabinoid receptors in our neural systems to help regulate. CBD Neural receptor
Full spectrum CBD Includes all active hemp-derived cannabinoids with <0.3% THC.
Broad spectrum CBD Includes most active hemp-derived cannabinoids except THC.
The FDA has not evaluated this product for safety or efficacy, and this product contains THC and natural CBD from hemp grown in the U.S.A.
Suggested/Recommended/Usage/Directions
Directions: Take 1 serving (1 softgel) orally, then swallow. Adjust serving if necessary.
Directions Take 1 softgel orally 1-2 times per day. Individual results may vary. Adjust serving if necessary.
Storage
Store in a cool, dry place away from direct sunlight.
Store in a cool, dry place away from direct sunlight.
Precautions
Keep away from children.
Consult a medical doctor before taking this or any other supplement, if you are pregnant, nursing, have or suspect a medical condition, or are taking any medications.
Keep out of reach of children.
May contain trace amounts <0.05% THC
This product has not been tested analyzed or approved by the Massachusetts department of agriculture or the FDA.
Do not consume if you are allergic to hemp
Warning: Reproductive harm - www.P65Warnings.ca.gov/food
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
The FDA has not evaluated this product for safety or efficacy. This product has not been evaluated by the Food and Drug Administration and is not intended to diagnose, treat, cure or prevent any disease.
This product has not been tested analyzed or approved by the Massachusetts department of agriculture or the FDA. The FDA has not evaluated this product for safety or efficacy, and this product contains THC and natural CBD from hemp grown in the U.S.A.
FDA Statement of Identity
Hemp Supplement
Seals/Symbols
H US Hemp Authority Certified
General Statements
The U.S. Hemp Authority Certification seal is only displayed by companies who meet the most stringent hemp industry standards.
Based on data collected from internal customer survey of 1,100 respondents.
Over 2 million satisfied CBDistillery customers! Learn more about our topicals, tinctures, and gummies at CBDistillery.com
Scan me!
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Relief + Relax CBD Softgels 30 mg by CBDistillery label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Relief + Relax CBD Softgels 30 mg by CBDistillery
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Broad Spectrum Hemp extract
Interacts with938 drugs
Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...
Broad Spectrum Hemp extract monograph & interactions- › Cannabidiol
Other (inactive) ingredients: Fractionated Coconut Oil, Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Relief + Relax CBD Softgels 30 mg by CBDistillery Drug Interactions
Relief + Relax CBD Softgels 30 mg contains a single active ingredient, and it has known interactions with 938 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Relief + Relax CBD Softgels 30 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Relief + Relax CBD Softgels 30 mg interact with 938 drugs. Click any drug to see the details.
1 of the 1 ingredient in Relief + Relax CBD Softgels 30 mg interact with drugs. Each result below shows which ingredient is responsible. Broad Spectrum Hemp extract
AlmotriptanAlmogran, Axert
How Almotriptan interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Alprazolam interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Amiloride, Hydrochlorothiazide interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs +1 Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAntihypertensive Drugs Minor
Interaction Summary
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
Read the full Broad Spectrum Hemp Extract + Ammonium Chloride interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmprenavirAgenerase
How Amprenavir interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Amprenavir interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Broad Spectrum Hemp Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Antithrombin Iii interactionApalutamideErleada
How Apalutamide interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
Read the full Broad Spectrum Hemp Extract + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Relief + Relax CBD Softgels 30 mg — through 1 ingredient. Tap an ingredient for the detail:
Broad Spectrum Hemp ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
Read the full Broad Spectrum Hemp Extract + Apixaban interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Relief + Relax CBD Softgels 30 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Broad Spectrum Hemp extract
Estrogens
Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.
Ace Inhibitors (Aceis)
Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.
Anticoagulant/Antiplatelet Drugs
Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.
Antihypertensive Drugs
Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.
Brand information
Manufacturer and brand details for Relief + Relax CBD Softgels 30 mg, from the product label.
CBDistillery
See all CBDistillery products- Name
- Balanced Health Botanicals, LLC
- Street Address
- 1720 South Bellaire Street
- City
- Denver
- State
- Colorado
- ZipCode
- 80222
- Web Address
- CBDistillery.com
Relief + Relax CBD Softgels 30 mg by CBDistillery: Common Questions
Does Relief + Relax CBD Softgels 30 mg by CBDistillery interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Relief + Relax CBD Softgels 30 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Relief + Relax CBD Softgels 30 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Relief + Relax CBD Softgels 30 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Hemp 12 references
- Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
- Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
- Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
- Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
- Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
- Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
- Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
- Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
- Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
- Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
- Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC