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Dietary supplement

Royal Jelly 1500 mg Ingredients & Drug Interactions

by Vitabase

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Royal Jelly 1500 mg is a dietary supplement by Vitabase with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Royal Jelly 1500 mg by Vitabase

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: royal jelly at 1500 mg per capsule. Royal jelly is a nutrient-rich secretion produced by honeybees; it's used in supplements for various health purposes.

The capsule itself is made from gelatin, with rice flour and magnesium stearate added as inactive ingredients to help with texture and shelf stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Royal Jelly's overall clinical evidence instead.

Moderate

Some clinical evidence supports Royal Jelly for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Menopausal symptoms — rated "Possibly Effective" (Natural Medicines).

Royal jelly is possibly effective for menopausal symptoms. For hay fever (allergic rhinitis), diabetes, and physical performance, the evidence suggests it's probably not effective.

For male pattern baldness (androgenic alopecia), there isn't enough reliable evidence to know whether it works.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal jelly is generally well tolerated in most people, but it carries a significant caveat: it can trigger serious allergic reactions in anyone with a history of asthma or atopy (a tendency toward allergic conditions). Reactions range from itching and hives to breathing problems, and in rare cases, anaphylaxis and death.

There isn't enough safety information to recommend royal jelly during pregnancy or while breastfeeding. One case report also documented bleeding in the colon after ingestion, though symptoms resolved after stopping the supplement.

If you have asthma or a history of allergies, talk with your doctor or pharmacist before trying this product.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Royal Jelly 1500 mg, double-check with your doctor or pharmacist if you take warfarin (Coumadin) — the bleeding risk is documented and serious. You should also confirm any blood pressure medications (antihypertensive drugs), since royal jelly may lower blood pressure further and cause it to drop too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Jelly 1500 mg may be worth considering if you're exploring options for menopausal symptoms and you don't have asthma or a tendency toward allergies. However, this product isn't the right choice if you take warfarin or blood pressure medications without first checking with your doctor or pharmacist — the interactions are documented and could matter.

If you have any history of allergic reactions, asthma, or atopy, discuss this product with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Jelly 1500 mg, straight from the product label.

Brand Vitabase
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 23, 2012
DSLD ID 6694
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Jelly 1500 mg by Vitabase, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Royal Jelly500 mg--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 capsule daily, preferably with meals.

Formulation

Contains no sugar, salt, wheat, yeast, gluten, corn, milk, soy, egg, or preservatives.

Precautions

Warning: Royal Jelly may cause an allergic reaction in some people.

Caution: Do Not Eat Freshness Packet. Keep in Bottle

KEEP OUT OF REACH OF CHILDREN.

DO NOT USE IF OUTER SEAL IS DAMAGED OR MISSING.

Seals/Symbols

Vb

General Statements

MADE IN THE U.S.A.

This Royal Jelly has been freeze-dried to maintain maximum stability and is among the finest products available.

Vitabase uses only high quality ingredients.

FDA Statement of Identity

DIETARY SUPPLEMENT

Formula

10-HDA (10-hydroxy-trans-2-decenoic acid) is one of the active, measurable components of Royal Jelly.

See for yourself

Royal Jelly 1500 mg by Vitabase label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Royal Jelly 1500 mg by Vitabase

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Royal Jelly

Interacts with
174 drugs
500 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Jelly 1500 mg by Vitabase Drug Interactions

Want to check YOUR meds against Royal Jelly 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Jelly 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Royal Jelly 1500 mg, from the product label.

Vitabase

See all Vitabase products
Name
Vitabase.com
City
Monroe
State
GA
ZipCode
30656
Pharmacist Counseling Corner

Royal Jelly 1500 mg by Vitabase: Common Questions

Does Royal Jelly 1500 mg by Vitabase interact with any medications?
Yes. Based on its ingredients, Royal Jelly 1500 mg has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Jelly 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is royal jelly safe if I have asthma or allergies?
No — royal jelly carries a significant risk if you have asthma or a history of allergies (atopy). People in these groups commonly experience itching, hives, eczema, and breathing problems, and in rare cases, serious reactions like anaphylaxis. If this describes you, talk with your doctor or pharmacist before considering this product.
Can I take royal jelly while pregnant or breastfeeding?
There isn't enough safety information to know whether royal jelly is safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in either situation.
Does royal jelly actually help with menopause symptoms?
Royal jelly is possibly effective for menopausal symptoms based on the evidence we hold, meaning some research suggests it may help, but more data would strengthen that finding. It's not proven, so results vary from person to person.
Will royal jelly help me lose weight or boost my physical performance?
The evidence doesn't support either use. For physical performance and diabetes, royal jelly appears probably not effective based on available research.
What are the most common side effects?
In people without asthma or allergies, royal jelly is generally well tolerated. In those with a history of asthma or atopy, common side effects include itching, hives, eczema, and breathing problems — which is why it's important to know your allergy history before taking it.
Does this product have any fillers?
Yes — besides the royal jelly, the capsule contains gelatin, rice flour, and magnesium stearate as inactive ingredients to hold everything together and keep it stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Royal Jelly 1500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Jelly 1500 mg label
Sources

Sources & How We Checked

Royal Jelly 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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