Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Rutin-500 Ingredients & Drug Interactions

by DC

Rutin-500 label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rutin-500 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rutin-500 is a dietary supplement by DC with 1 active ingredient. Its ingredients are commonly taken for varicose veins and chronic venous insufficiency, hemorrhoids, easy bruising and fragile capillaries.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rutin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Rutin-500 by DC

Ask about any prescription or over-the-counter medication and we check it for interactions with Rutin-500 by DC — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Rutin-500 by DC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Rutin-500 contains one active ingredient: rutin, a plant compound found naturally in foods like buckwheat, citrus peel, and apple skin. The tablet also contains several inactive ingredients—calcium carbonate, cellulose, vegetable stearic acid, and silica—which are fillers and binders that help hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Rutin product and its label doesn't state a use — see Rutin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for rutin isn't established yet. Our data shows insufficient reliable evidence to rate it for aging skin, autism spectrum disorder, inflammatory bowel disease, diabetes, exercise-induced respiratory infections, or hemorrhoids.

That doesn't mean it doesn't work—it means the research we have isn't strong enough to say so confidently. If you're considering it for one of these uses, ask your doctor what the current evidence supports.

The evidence, ingredient by ingredient Rutin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rutin is generally well tolerated when you eat it in food or take it as a short-term supplement, though high-quality long-term safety data are limited. A small number of people may experience headache, flushing, or rashes.

The safety data for supplement doses during breastfeeding are unknown, so it's best to avoid it if you're nursing unless your doctor advises otherwise. Pregnancy safety is rated as likely safe.

Side effects, ingredient by ingredient Rutin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rutin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes medication—insulin, metformin, glipizide, glyburide, or any other drug that lowers blood sugar—check with your doctor or pharmacist before starting Rutin-500. Moderate-severity interactions are documented, and combining them could raise your risk of low blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Rutin-500 may be worth considering if you're interested in a plant-derived supplement, but the evidence for specific health claims isn't solid yet. The main thing to watch is if you take antidiabetes drugs—talk with your doctor or pharmacist first to make sure combining them is safe for you.

Long-term safety data are still limited, so this is best used short-term and under guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rutin-500, straight from the product label.

Brand DC
Net contents 90 Veg Tablet(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 266283
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rutin-500 by DC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
IngredientAmount% DV
Rutin500 mg--

Other ingredients: Calcium Carbonate, Cellulose, Vegetable Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

Formulation

Manufactured in our own state-of-the-art FDA Registered Facility (Registration #1023013) using Good Manufacturing Practices (GMPs) assuring correct potencies, freshness, quality and purity

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Gluten free

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Seals/Symbols

Quali Pure

Formula

Rutin

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 tablet daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rutin-500 by DC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rutin-500 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rutin-500 by DC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Rutin

Interacts with
86 drugs
500 mg per serving

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins...

Rutin monograph & interactions

Other (inactive) ingredients: Calcium Carbonate, Cellulose, Vegetable Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rutin-500 by DC Drug Interactions

Want to check YOUR meds against Rutin-500?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Rutin 86

Individual Drug Interactions

The ingredients in Rutin-500 interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rutin-500 interact with drugs. Each result below shows which ingredient is responsible. Rutin

Each ingredient & the kinds of drugs it affects

For each ingredient in Rutin-500 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rutin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking rutin with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that rutin has hypoglycemic effects.

Likelihood Possible Evidence D
Rutin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rutin-500, from the product label.

DC

See all DC products
Name
Dee Cee Laboratories, Inc.
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Rutin-500 by DC: Common Questions

Does Rutin-500 by DC interact with any medications?
Yes. Based on its ingredients, Rutin-500 has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rutin-500 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Rutin-500 if I'm pregnant?
Pregnancy safety for rutin is rated as likely safe, so the data suggest it's okay. That said, any supplement decision in pregnancy is personal—talk it over with your doctor or midwife to make sure it's right for your situation.
What side effects should I watch for?
A small number of people report headache, flushing, or rashes when taking rutin. These aren't common, but if you notice any rash or unusual symptoms, stop and let your doctor know.
Does Rutin-500 actually work for any specific condition?
Our data show insufficient reliable evidence to rate rutin for aging skin, autism spectrum disorder, inflammatory bowel disease, diabetes, exercise-induced respiratory infections, or hemorrhoids. The research isn't strong enough yet to say it works for any of these.
Is it safe to take long-term?
Rutin is generally well tolerated in the short term, but high-quality long-term safety data are limited. We don't have enough information to say how safe it is over years of use, so check with your doctor if you're thinking about taking it indefinitely.
Can I breastfeed while taking Rutin-500?
Safety during breastfeeding is unknown, so it's best to avoid supplement doses of rutin while nursing. Talk with your doctor or pharmacist about whether it's okay for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Rutin-500 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rutin-500 label
Go deeper

The Full Monographs Behind Rutin-500’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rutin

Interacts with 86 drugs

Rutin is a plant flavonoid (often taken from buckwheat or citrus) that people use mainly for blood vessel and circulation problems like varicose veins and hemorrhoids. The evidence is limite...

Read the full Rutin monograph →
Sources

Sources & How We Checked

Rutin-500's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rutin 2 references
  1. Mehta DK (Ex Ed). British National Formulary, Number 37. British Medical Association and Royal Pharmaceutical Society of Great Britain: London, England, March 1999.
  2. Sun C, Wang L, Sun J, Wang Z, Tang Z. Hypoglycemic and hypolipidemic effects of rutin on hyperglycemic rats. J Tradit Chin Med. 2020;40(4):640-645.

See these in context on the Rutin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team