Sambucus Elderberry Ingredients & Drug Interactions
by GNC
What is this page for?
First and foremost: checking Sambucus Elderberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sambucus Elderberry is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry Fruit Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sambucus Elderberry by GNC
Ask about any prescription or over-the-counter medication and we check it for interactions with Sambucus Elderberry by GNC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Sambucus Elderberry by GNC
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Elderberry.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
- For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sambucus Elderberry, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sambucus Elderberry by GNC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Elderberry Fruit Extract, Powder | 500 mg | -- |
Other ingredients: Hypromellose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
5 ingredients in 1 pack for easy, everyday immune support. That's the GNC difference.
Defend your daily wellness! Includes essential ingredients for premium immune health support, crafted by experts for your:
General Statements
Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements.
Value size 30-day supply 30 Packs/30-day supply
Actual size
For more information: 1-888-462-2548
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formula
Immune system Features Vitamin C, a powerful antioxidant to support your immune system, and elderberry
Comprehensive, daily support for immune health featuring zinc, Vitamin C, Vitamin D-3, sambucus elderberry, & echinacea 5-in-1 pack Sambucus elderberry
Each pack contains:
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take the contents of one pack daily with food.
Precautions
Warning: Cancer and reproductive harm - www.P65Warnings.ca.gov
Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Discontinue use two weeks prior to surgery.
Keep out of reach of children.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sambucus Elderberry by GNC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sambucus Elderberry by GNC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Elderberry Fruit Extract, Powder
Interacts with121 drugs
Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...
Elderberry Fruit Extract, Powder monograph & interactionsOther (inactive) ingredients: Hypromellose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Sambucus Elderberry by GNC Drug Interactions
Sambucus Elderberry contains a single active ingredient, and it has known interactions with 121 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Sambucus Elderberry?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sambucus Elderberry interact with 121 drugs. Click any drug to see the details.
1 of the 1 ingredient in Sambucus Elderberry interact with drugs. Each result below shows which ingredient is responsible. Elderberry Fruit Extract, Powder
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Abrocitinib interactionAdalimumabHumira
How Adalimumab interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Alemtuzumab interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Azathioprine interactionBasiliximabSimulect
How Basiliximab interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Beclomethasone Dipropionate interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Betamethasone Valerate interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Bimekizumab-bkzx interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Ciclesonide interactionCisplatinPlatinol-AQ
How Cisplatin interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Cisplatin interactionCladribineLeustatin, Mavenclad
How Cladribine interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Cladribine interactionCopanlisibAliqopa
How Copanlisib interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Copanlisib interactionCortisone AcetateCortisone Tablets, Cortone
How Cortisone Acetate interacts with Sambucus Elderberry — through 1 ingredient. Tap an ingredient for the detail:
Elderberry Fruit Extract, PowderImmunosuppressants Moderate
Interaction Summary
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Read the full Elderberry Fruit Extract, Powder + Cortisone Acetate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sambucus Elderberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Elderberry Fruit Extract, Powder
Immunosuppressants
Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.
Pazopanib (Votrient)
Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
Brand information
Manufacturer and brand details for Sambucus Elderberry, from the product label.
GNC
See all GNC products- Name
- GNC Holdings, LLC
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- GNC.com
Sambucus Elderberry by GNC: Common Questions
Does Sambucus Elderberry by GNC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sambucus Elderberry is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sambucus Elderberry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Sambucus Elderberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Elderberry 6 references
- Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
- Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
- European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
- Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
- Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
- Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC