Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Goodbye Stress Berry Verbena Ingredients & Drug Interactions

by OLLY

Goodbye Stress Berry Verbena label
See full label image
Gummy Or Jelly Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Goodbye Stress Berry Verbena against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Goodbye Stress Berry Verbena is a dietary supplement by OLLY with 3 active ingredients. Its ingredients are commonly taken for anxiety and stress, relaxation and calm, sleep support.Based on those ingredients, 581 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are L-Theanine, Gamma-Aminobutyric Acid, Lemon Balm aerial parts extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Goodbye Stress Berry Verbena by OLLY

Ask about any prescription or over-the-counter medication and we check it for interactions with Goodbye Stress Berry Verbena by OLLY — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Goodbye Stress Berry Verbena by OLLY

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Goodbye Stress Berry Verbena contains three active ingredients. L-Theanine is an amino acid that may support cognitive function.

GABA (gamma-aminobutyric acid) is a neurotransmitter your brain naturally produces. Lemon balm aerial parts extract comes from the plant's leaves and stems, and the product facts show it's been studied for cold sore care and stress.

The rest of the gummy is made up of inactive ingredients — glucose syrup, beet sugar, gelatin, natural flavor, citric acid, and others that give it texture and taste.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: keep calm and stay alert.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Stress, Insomnia, Psychological well-being, relaxation — and 2 related terms.
  • The strongest evidence on file: Lemon Balm is rated "Possibly Effective" for Stress (Natural Medicines).
  • Also on file: Lemon Balm is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Insomnia.
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety, Insomnia, Stress, Psychological well-being.

Here's what the research shows for each ingredient in this product. L-Theanine is possibly effective for cognitive function, but there's insufficient evidence to rate it for age-related cognitive decline, Alzheimer's disease, or anxiety disorders like GAD and OCD.

GABA has insufficient evidence for the conditions it's been studied for — anxiety, ADHD, athletic performance, and a few others. Lemon balm is possibly effective for both cold sores and stress, and also possibly effective for depression.

So this product has some evidence behind stress and mood support from lemon balm, but the evidence for the other two ingredients in those areas isn't established yet in the data we hold.

The evidence, ingredient by ingredient Theanine Gamma-aminobutyric Acid (gaba) Lemon Balm

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-Theanine is generally well tolerated for short-term use in healthy adults, though long-term safety hasn't been well studied. People have reported headaches, drowsiness, increased sleep duration, and more vivid dreams.

GABA also seems generally well tolerated in the short term, with reports of drowsiness, nausea, gastric upset, minor throat burning, and muscle weakness in some people. Lemon balm is generally well tolerated for short-term use, and dizziness or sedation don't appear to happen more often than with a placebo.

For pregnancy, the safety data isn't there for L-Theanine or GABA — both should be avoided unless your doctor advises otherwise. Lemon balm is also best avoided during pregnancy unless your doctor says it's okay.

When breastfeeding, L-Theanine and GABA should be avoided, while lemon balm should be used only with caution and guidance from your doctor.

Side effects, ingredient by ingredient Theanine Gamma-aminobutyric Acid (gaba) Lemon Balm

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Lemon Balm, Gamma-aminobutyric Acid (gaba), Theanine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 581 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check blood pressure medications (antihypertensive drugs) — both L-Theanine and GABA may lower your pressure further. Next, check thyroid hormone replacement therapy, since lemon balm might interfere with it.

Also check CNS depressants like sleeping pills and anxiety medications, which could have additive sedating effects. Finally, if you're on serotonergic drugs like antidepressants, that's worth reviewing with your pharmacist as well.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is aimed at stress and mood support, with some research backing lemon balm for those purposes. If you take blood pressure medication, thyroid hormone replacement, or sleep aids or anti-anxiety drugs, you need to double-check with your pharmacist before you start — those are the biggest interaction red flags here.

Otherwise, chat with us if you have questions about your specific medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Goodbye Stress Berry Verbena, straight from the product label.

Brand OLLY
Barcode (UPC) 840160201448
Net contents 120 Gummy(ies)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 295130
Product type Other Combinations
Supplement form Gummy Or Jelly
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Goodbye Stress Berry Verbena by OLLY, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
60
UPC/BARCODE
840160201448
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
L-Theanine50 mg--
Added Sugars2 Gram(s)4%
Total Sugars2 Gram(s)--
Gamma-Aminobutyric Acid100 mg--
Lemon Balm aerial parts extract75 mg--

Other ingredients: Glucose Syrup, Beet Sugar, Water, Gelatin, Natural flavor, Citric Acid, Pepper Juice, Apple, Tomato, Sweet Potato Juice, Radish Juice, Pectin, Vegetable Oil, Carnauba wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Keep calm & stay alert

No synthetic flavors or colors Gluten free

Formula

GABA, L-Theanine & Lemon Balm

Berry verbena with other natural flavors

The goods inside GABA This fast working (within 30-60 minutes!) amino acid supports a relaxed state of mind to help combat the acute effects of stress. Go Gaba! L-theanine GABA's partner in sublime - this ingredient goes right to work in your brain to help you keep your cool. Lemon balm A soothing botanical that has been used for centuries to help quiet the mind.

Naturally tasty A zen blend of strawberry and lemon verbena.

FDA Statement of Identity

Dietary Supplement

These statements have not been evaluated by the food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Tear here 1. Hold open middle flap with finger 2. Pull both sides apart to open

Multi-layer Pouch how2recycle.info

Facebook Instagram Pinterest Twitter Olly.com

Precautions

This package is child resistant.

Processed in a facility with products that may contain soy, egg, peanuts, tree nuts, milk, fish, shellfish and wheat.

Take only as directed. Do not exceed suggested use. Intended for occasional use only.

If you have a medical condition, are on medication or are pregnant or nursing, please seek the advice of a qualified health care professional before using.

Not intended for use in children. Keep out of the reach of children.

Do not use if pouch is torn or open.

Suggested/Recommended/Usage/Directions

Take as needed No food or water necessary.

Suggested use: take 2 gummies per day as needed. Chew thoroughly before swallowing.

Storage

Store in a cool, dry place.

Seals/Symbols

Certified B Corporations Contents Certified NSF

Brand IP Statement(s)

Copyright 2021 OLLY PBC

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Goodbye Stress Berry Verbena by OLLY label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Goodbye Stress Berry Verbena label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Goodbye Stress Berry Verbena by OLLY

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Theanine

Interacts with
565 drugs
50 mg per serving

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong dro...

L-Theanine monograph & interactions

Gamma-Aminobutyric Acid

Interacts with
419 drugs
100 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma-Aminobutyric Acid monograph & interactions

Lemon Balm aerial parts extract

Interacts with
264 drugs
75 mg per serving

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold so...

Lemon Balm aerial parts extract monograph & interactions

Other (inactive) ingredients: Glucose Syrup, Beet Sugar, Water, Gelatin, Natural flavor, Citric Acid, Pepper Juice, Apple, Tomato, Sweet Potato Juice, Radish Juice, Pectin, Vegetable Oil, Carnauba wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Goodbye Stress Berry Verbena by OLLY Drug Interactions

Want to check YOUR meds against Goodbye Stress Berry Verbena?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
581Drugs
435 Moderate 146 Minor

Ingredients driving the most interactions

L-Theanine 565
Gamma-Aminobutyric Acid 419
Lemon Balm aerial parts extract 264

Individual Drug Interactions

The ingredients in Goodbye Stress Berry Verbena interact with 581 drugs. Click any drug to see the details.

3 of the 3 ingredients in Goodbye Stress Berry Verbena interact with drugs. Each result below shows which ingredient is responsible. L-Theanine Gamma-Aminobutyric Acid Lemon Balm aerial parts extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Goodbye Stress Berry Verbena with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Theanine3 drug types · 565 drugs

Antihypertensive Drugs

Theanine might lower blood pressure, potentiating the effects of antihypertensive drugs.
Animal research shows that theanine can lower blood pressure in spontaneously hypertensive animals. Theoretically, concomitant use of theanine and antihypertensive drugs might potentiate the antihypertensive activity.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, theanine might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Theoretically, theanine may compete with glutamate and/or increase plasma gamma-aminobutyric acid (GABA) levels, which could cause CNS depression. In one clinical study, some subjects taking oral theanine reported drowsiness.

Likelihood Unlikely Evidence D
Serotonergic Drugs

Clinical studies regarding the effects of L-theanine on serotonin levels are conflicting. Some studies suggest it can increase serotonin levels in the brain while others report that it may decrease them. Nevertheless, there have been no reports of l-theanine being a causative agent in serotonergic-related side effects or serotonin syndrome.

Likelihood Unlikely Evidence C
L-Theanine full monograph & interactions

Gamma-Aminobutyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma-Aminobutyric Acid full monograph & interactions

Lemon Balm aerial parts extract2 drug types · 264 drugs

Cns Depressants

Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.

Likelihood Possible Evidence B
Thyroid Hormone

Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.

Likelihood Possible Evidence D
Lemon Balm aerial parts extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Goodbye Stress Berry Verbena, from the product label.

OLLY

See all OLLY products
Name
OLLY Public Benefit Corp.
City
San Francisco
State
CA
ZipCode
94111
Phone Number
1-844-439-6559
Web Address
OLLY.com
Pharmacist Counseling Corner

Goodbye Stress Berry Verbena by OLLY: Common Questions

Does Goodbye Stress Berry Verbena by OLLY interact with any medications?
Yes. Based on its ingredients, Goodbye Stress Berry Verbena has a known interaction with 581 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Goodbye Stress Berry Verbena contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't strong enough for any of the three ingredients during pregnancy, so both L-Theanine and GABA should be avoided unless your doctor advises it's okay — same goes for lemon balm. If you're breastfeeding, L-Theanine and GABA should be avoided, and lemon balm can only be used if you talk to your doctor first. This is something to discuss with your OB or your pharmacist for personalized advice.
What side effects might I notice?
L-Theanine may cause headaches, drowsiness, or more vivid dreams. GABA can bring on drowsiness, nausea, or an upset stomach. Lemon balm hasn't shown side effects in studies that stand out above placebo. Overall, people tolerate these ingredients short-term, but if anything bothers you, stop and let your pharmacist know.
How long can I safely take this?
Long-term safety hasn't been well studied for any of these ingredients. The data we have is for short-term use in healthy adults. If you're thinking of taking it regularly for weeks or months, that's a conversation to have with your pharmacist or doctor.
Is there evidence this actually helps with stress?
Lemon balm in this product is possibly effective for stress. L-Theanine is possibly effective for cognitive function, but the evidence for stress and anxiety specifically is insufficient right now. So you've got some support from the lemon balm, but the overall evidence for the product as a stress reliever isn't firm yet.
What are these ingredients actually for?
L-Theanine is an amino acid that may help with focus and cognition. GABA is a natural brain chemical involved in relaxation. Lemon balm is a plant extract that's been studied for both cold sores and mood support. Together, they're intended to address stress and general wellness.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Goodbye Stress Berry Verbena is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Goodbye Stress Berry Verbena label
Go deeper

The Full Monographs Behind Goodbye Stress Berry Verbena’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theanine

Interacts with 565 drugs

Theanine (usually L-theanine) is an amino acid found naturally in tea leaves that many people take to feel calmer and less stressed without strong drowsiness. Early research suggests it may...

Read the full Theanine monograph → Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph → Herb & supplement monograph

Lemon Balm

Interacts with 264 drugs

Lemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...

Read the full Lemon Balm monograph →
Sources

Sources & How We Checked

Goodbye Stress Berry Verbena's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theanine 6 references
  1. Yokogoshi H, Kobayashi M. Hypotensive effect of gamma-glutamylethylamide in spontaneously hypertensive rats. Life Sci 1998;62:1065-8.
  2. Haskell, C. F., Kennedy, D. O., Milne, A. L., Wesnes, K. A., and Scholey, A. B. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol.Psychol. 2008;77(2):113-122. PubMed
  3. Yokogoshi, H., Kato, Y., Sagesaka, Y. M., Takihara-Matsuura, T., Kakuda, T., and Takeuchi, N. Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats. Biosci.Biotechnol.Biochem. 1995;59(4):615-618. PubMed
  4. Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011;16(4):348-
  5. Hidese S, Ota M, Wakabayashi C, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr 2017;29(2):72-9.
  6. Tsuchiya T, Honda H, Oikawa M, et al. Oral administration of the amino acids cystine and theanine attenuates the adverse events of S-1 adjuvant chemotherapy in gastrointestinal cancer patients. Int J Clin Oncol 2016;21(6):1085-90. PubMed

See these in context on the Theanine monograph →

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Lemon Balm 12 references
  1. Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
  2. Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
  3. Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
  4. Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
  5. Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
  6. Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
  7. Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
  8. Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
  9. Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
  10. Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
  11. Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
  12. Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.

See these in context on the Lemon Balm monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team